Search Results - "Spranger, Matthias"

36 months observational clinical study of 38 adult Pompe disease patients under alglucosidase alfa enzyme replacement therapy by Regnery, Caroline, Kornblum, Cornelia, Hanisch, Frank, Vielhaber, Stefan, Strigl-Pill, Nicola, Grunert, Birgit, Müller-Felber, Wolfgang, Glocker, Franz Xaver, Spranger, Matthias, Deschauer, Marcus, Mengel, Eugen, Schoser, Benedikt

“…Objectives Glycogen storage disease type 2(GSD2)/Pompe disease is characterized by respiratory and skeletal muscle weakness and atrophy, resulting in…”
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Legislation on direct-to-consumer genetic testing in seven European countries by Borry, Pascal, van Hellemondt, Rachel E, Sprumont, Dominique, Jales, Camilla Fittipaldi Duarte, Rial-Sebbag, Emmanuelle, Spranger, Tade Matthias, Curren, Liam, Kaye, Jane, Nys, Herman, Howard, Heidi

“…An increasing number of private companies are now offering direct-to-consumer (DTC) genetic testing services. Although a lot of attention has been devoted to…”
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Intraventricular brain-derived neurotrophic factor reduces infarct size after focal cerebral ischemia in rats by Schäbitz, W R, Schwab, S, Spranger, M, Hacke, W

“…Brain-derived neurotrophic factor (BDNF), acting through the high-affinity receptor tyrosine kinase (TrkB), is widely distributed throughout the central…”
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Brain-Derived Neurotrophic Factor Improves Long-Term Potentiation and Cognitive Functions after Transient Forebrain Ischemia in the Rat by Kiprianova, Irina, Sandkühler, Jürgen, Schwab, Stefan, Hoyer, Siegfried, Spranger, Matthias

“…We investigated the effect of brain-derived neurotrophic factor (BDNF) on hippocampal long-term potentiation (LTP) and cognitive functions after global…”
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Macrophage-induced cytotoxicity of N-methyl-D-aspartate receptor positive neurons involves excitatory amino acids rather than reactive oxygen intermediates and cytokines by Piani, D, Spranger, M, Frei, K, Schaffner, A, Fontana, A

“…The co-localization of activated macrophages and damaged neurons observed in brain injury and degenerative brain diseases may hint to macrophage-induced…”
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Manganese Augments Nitric Oxide Synthesis in Murine Astrocytes: A New Pathogenetic Mechanism in Manganism? by Spranger, Matthias, Schwab, Stefan, Desiderato, Stephanie, Bonmann, Eckhard, Krieger, Derk, Fandrey, Joachim

“…Since manganese (Mn2+) is known to be sequestered in glial cells, we investigated possible neurotoxic mechanisms involving astrocytesin vitro.Low…”
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Die “history of safe use” im europäischen Gentechnikrecht by Spranger, Tade Matthias

“…Zusammenfassung Die “grüne” Gentechnik ist seit jeher ein spannungsreiches Feld: Während die Befürworter im Interesse hehrer Ziele eine “technikfreundlichere”…”
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Adenosine-induced expression of interleukin-6 in astrocytes through protein kinase A and NF-IL-6 by Schwaninger, Markus, Petersen, Nicole, Prinz, Simone, Sallmann, Svea, Neher, Mike, Spranger, Matthias

“…In various neurologic diseases, astrocytes express interleukin‐6 (IL‐6), which is an endogenous pyrogen, a neuroprotective factor, and a regulator of the…”
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Gait feature analysis of polyneuropathy patients by Xingchen Wang, Kuzmicheva, Olena, Spranger, Matthias, Graser, Axel

“…Polyneuropathy (PNP) and aging both bring changes to the walking pattern of elderly people. However, the identification methods of PNP from gait patterns were…”
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Usability and acceptability by a younger and older user group regarding a mobile robot-supported gait rehabilitation system by Eicher, Cornelia, Haesner, Marten, Spranger, Matthias, Kuzmicheva, Olena, Gräser, Axel, Steinhagen-Thiessen, Elisabeth

“…The aim of the study was to identify differences regarding usability, acceptability, and barriers of usage of a robot-supported gait rehabilitation system…”
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Excess glutamate in the cerebrospinal fluid in bacterial meningitis by Spranger, Matthias, Krempien, Sebastian, Schwab, Stefan, Maiwald, Matthias, Bruno, Kathleen, Hacke, Werner

“…We investigated possible neurotoxic components in the cerebrospinal fluid (CSF) of patients with bacterial meningitis. On murine cerebellar neuronal cell…”
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Brain Patents as a Legal or Societal Challenge? by Spranger, Tade Matthias

“…Patents relating to the human brain and its functions regularly fulfil the general patent requirements. In some cases, however, the inventions in question…”
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Beck, Felix: Self-Spreading Biotechnology and International Law. Prevention, Responsibility, and Liability in a Transboundary Context by Spranger, Tade Matthias

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Beck, Felix: Self-Spreading Biotechnology and International Law. Prevention, Responsibility, and Liability in a Transboundary Context by Spranger, Tade Matthias

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Gait assessment system based on novel gait variability measures by Xingchen Wang, Ristic-Durrant, Danijela, Spranger, Matthias, Graser, Axel

“…In this paper, a novel gait assessment system based on measures of gait variability reflected through the variability of shapes of gait cycles trajectories is…”
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An Innovation Principle in Gene Technology Law? by Spranger, Tade Matthias

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Thrombolysis in acute ischemic stroke: controlled trials and clinical experience by Hacke, W, Brott, T, Caplan, L, Meier, D, Fieschi, C, von Kummer, R, Donnan, G, Heiss, W D, Wahlgren, N G, Spranger, M, Boysen, G, Marler, J R

“…Thrombolytic therapy with recombinant tissue plasminogen activator (rtPA) is approved in the United States for treatment of acute ischemic stroke. Approval was…”
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Legislation on direct-to-consumer genetic testing in seven European countries: This article has been changed from an Article to Policy since Advance Online Publication by BORRY, Pascal, VAN HELLEMONDT, Rachel E, SPRUMONT, Dominique, DUARTE JALES, Camilla Fittipaldi, RIAL-SEBBAG, Emmanuelle, MATTHIAS SPRANGER, Tade, CURREN, Liam, KAYE, Jane, NYS, Herman, HOWARD, Heidi

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Barbiturate coma in severe hemispheric stroke: Useful or obsolete? by Schwab, Stefan, Spranger, Matthias, Schwarz, Stefan, Hacke, Werner

“…Barbiturates are administered in a variety of clinical conditions to control elevated intracranial pressure (ICP). However, their routine use to treat elevated…”
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Superoxide dismutase activity in serum of patients with acute cerebral ischemic injury correlation with clinical course and infarct size by SPRANGER, M, KREMPIEN, S, SCHWAB, S, DONNEBERG, S, HACKE, W

“…Superoxide dismutase (SOD) is one of the major free radical scavenging systems that might play a role in both degenerative and acute diseases of the central…”
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