Search Results - "Spranger, J"
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A prospective observational study of post-COVID-19 chronic fatigue syndrome following the first pandemic wave in Germany and biomarkers associated with symptom severity
Published in Nature communications (30-08-2022)“…A subset of patients has long-lasting symptoms after mild to moderate Coronavirus disease 2019 (COVID-19). In a prospective observational cohort study, we…”
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High-fat Diet and Physical Exercise Differentially Modulate Adult Neurogenesis in the Mouse Hypothalamus
Published in Neuroscience (21-02-2019)“…•High-fat diet (HFD) increased neurogenesis and the fraction of POMC neurons in the adult arcuate nucleus (ArcN).•Physical exercise increased cell…”
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Exercise prevents high-fat diet-induced impairment of flexible memory expression in the water maze and modulates adult hippocampal neurogenesis in mice
Published in Neurobiology of learning and memory (01-05-2016)“…•High-fat diet (HFD) initiated in adolescent but not adult mice impaired flexible memory expression in the water maze.•Concurrent (long-term) physical exercise…”
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4
EFhd2/Swiprosin-1 is a common genetic determinator for sensation-seeking/low anxiety and alcohol addiction
Published in Molecular psychiatry (01-05-2018)“…In many societies, the majority of adults regularly consume alcohol. However, only a small proportion develops alcohol addiction. Individuals at risk often…”
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Measuring Energy Expenditure in extracorporeal lung support Patients (MEEP) – Protocol, feasibility and pilot trial
Published in Clinical nutrition (Edinburgh, Scotland) (01-02-2018)“…Summary Purpose Indirect calorimetry (IC) is the gold standard for measuring energy expenditure (EE). Due to O2 uptake and CO2 removal by both the…”
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Design and cohort description of the InterAct Project: an examination of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes in the EPIC Study
Published in Diabetologia (01-09-2011)“…Aims/hypothesis Studying gene–lifestyle interaction may help to identify lifestyle factors that modify genetic susceptibility and uncover genetic loci exerting…”
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Effects of marked weight loss on plasma levels of adiponectin, markers of chronic subclinical inflammation and insulin resistance in morbidly obese women
Published in International Journal of Obesity (01-07-2005)“…Obesity is linked to the insulin resistance syndrome (IRS), type 2 diabetes (T2D) and cardiovascular disease. Markers of chronic subclinical inflammation such…”
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Effect of Human Body Weight Changes on Circulating Levels of Peptide YY and Peptide YY3–36
Published in The journal of clinical endocrinology and metabolism (01-02-2007)“…Background: Recent findings suggest that low plasma peptide YY (PYY) levels may contribute to diet-induced human obesity and justify PYY replacement therapy…”
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Hyperostosis in siblings
Published in South African medical journal (25-05-2016)“…Infantile cortical hyperostosis - Caffey-Silverman disease - is a familial disorder manifesting in the late fetal period or infancy with excessive periosteal…”
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Current clinical practice for thromboprophylaxis management in patients with Cushing's syndrome across reference centers of the European Reference Network on Rare Endocrine Conditions (Endo-ERN)
Published in Orphanet journal of rare diseases (03-05-2022)“…Cushing's syndrome (CS) is associated with an hypercoagulable state and an increased risk of venous thromboembolism (VTE). Evidence-based guidelines on…”
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Microalbuminuria is a major determinant of elevated plasma retinol-binding protein 4 in type 2 diabetic patients
Published in Kidney international (01-08-2007)“…Plasma retinol-binding protein 4 (RBP4) may be a new adipokine linked to obesity-induced insulin resistance and type 2 diabetes. The impact of diabetic…”
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Correction to: Identification of an intracellular metabolic signature impairing beta cell function in the rat beta cell line INS-1E and human islets
Published in Diabetologia (01-03-2019)“…As part of an institutional investigation by University of Bremen, the work carried out by Kathrin Maedler’s laboratory has been reviewed…”
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Specific skeletal muscle sphingolipid compounds in energy expenditure regulation and weight gain in Native Americans of Southwestern heritage
Published in International Journal of Obesity (01-10-2017)“…Background/Objectives: In animal models, a role in the regulation of energy expenditure (EE) has been ascribed to sphingolipids, active components of cell…”
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A dietary pattern protective against type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study cohort
Published in Diabetologia (01-06-2005)“…The aim of this study was to identify a dietary pattern associated with diabetes-related biomarkers and to investigate whether this pattern is associated with…”
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Impact of cereal fibre on glucose-regulating factors
Published in Diabetologia (01-11-2005)“…Insoluble dietary fibre intake is associated, by unknown mechanisms, with a reduced risk of type 2 diabetes. We investigated whether a short-term dietary…”
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Leptin and endocrine parameters in marathon runners
Published in International journal of sports medicine (01-03-2012)“…Endurance training may lead to different hormonal alterations e. g., exercised induced hypothalamic ovarian/testicular dysfunction. The aim of this study was…”
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The Impact of Insulin-Independent, Glucagon-Induced Suppression of Total Ghrelin on Satiety in Obesity and Type 1 Diabetes Mellitus
Published in The journal of clinical endocrinology and metabolism (01-10-2013)“…Aims/Hypothesis: The mechanisms underlying glucagon-induced satiety are incompletely understood. The glucagon-induced reduction in total ghrelin exerted at the…”
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Circulating insulin-like growth factor binding protein-3 predicts one-year outcome after ischemic stroke
Published in Experimental and clinical endocrinology & diabetes (01-09-2015)“…Insulin-like Growth Factor-1 (IGF-1) and Insulin-like Growth Factor Binding Protein-3 (IGFBP-3) have been ascribed neuroprotective effects. We sought to…”
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Identification of an intracellular metabolic signature impairing beta cell function in the rat beta cell line INS-1E and human islets
Published in Diabetologia (01-10-2011)“…Aims/hypothesis Chronic hyperglycaemia promotes the progressive failure of pancreatic beta cells in patients with type 2 diabetes mellitus, a clinically highly…”
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Improved insulin sensitivity, preserved beta cell function and improved whole-body glucose metabolism after low-dose growth hormone replacement therapy in adults with severe growth hormone deficiency: a pilot study
Published in Diabetologia (01-07-2010)“…Aims/hypothesis Growth hormone-deficient patients show deterioration of insulin sensitivity and beta cell function. High-dose growth hormone treatment often…”
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