Search Results - "Spotnitz, W D"

Use of Fibrin Sealant to Reduce Bloody Drainage and Hemoglobin Loss After Total Knee Arthroplasty : A Brief Note on a Randomized Prospective Trial by Wang, G J, Hungerford, D S, Savory, C G, Rosenberg, A G, Mont, M A, Burks, S G, Mayers, S L, Spotnitz, W D

“…BackgroundA phase-III trial that included fifty-three patients undergoing unilateral primary total knee arthroplasty with cement was conducted to investigate…”
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Fibrin sealant in the United States: clinical use at the University of Virginia by Spotnitz, W D

“…Fibrin sealant use in the United States has been limited because of the lack of a commercially available, government approved product. However, the significant…”
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Mechanism of Ischemic Mitral Regurgitation: An Experimental Evaluation by Kaul, Sanjiv, Spotnitz, William D, Glasheen, William P, Touchstone, Dale A

“…BACKGROUNDPapillary muscle dysfunction (PMD) has been implicated in the pathogenesis of ischemic mitral regurgitation (MR). We hypothesized that ischemic MR is…”
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Fibrin tissue adhesives by Martinowitz, U, Spotnitz, W D

“…FTA is a promising adjunct treatment in many fields of surgery, mainly in patients with acquired and congenital bleeding disorders or in procedures with high…”
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Albumin microbubble persistence during myocardial contrast echocardiography is associated with microvascular endothelial glycocalyx damage by LINDNER, J. R, ISMAIL, S, SPOTNITZ, W. D, SKYBA, D. M, JAYAWEERA, A. R, KAUL, S

“…We hypothesized that the persistence of albumin microbubbles within the myocardium during crystalloid cardioplegia (CP) infusion and ischemia-reperfusion (I-R)…”
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The role of sutures and fibrin sealant in wound healing by Spotnitz, W D, Falstrom, J K, Rodeheaver, G T

“…Sutures and fibrin sealant are important surgical aids for facilitating wound closure and creating an optimal setting for wound healing. Most commonly, sutures…”
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Mechanism of mitral leaflet excursion by Dent, J M, Spotnitz, W D, Nolan, S P, Jayaweera, A R, Glasheen, W P, Kaul, S

“…The factors that influence the extent of mitral leaflet opening (MLO) and closure (MLC) have not been defined. We hypothesized that left ventricular (LV)…”
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Neurosurgical applications of fibrin glue: augmentation of dural closure in 134 patients by Shaffrey, C I, Spotnitz, W D, Shaffrey, M E, Jane, J A

“…In a wide variety of neurosurgical procedures performed on 134 patients over a 3-year period, fibrin glue has been applied as an adjunct to dural closure…”
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Commercial fibrin sealants in surgical care by Spotnitz, William D

“…Fibrin sealants can be a valuable adjunct to surgical procedures. A variety of commercial products have been developed. Specific uses include hemostasis,…”
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Reperfusion injury significantly impacts clinical outcome after pulmonary transplantation by King, Robert C, Binns, Oliver A.R, Rodriguez, Filiberto, Kanithanon, R.Chai, Daniel, Thomas M, Spotnitz, William D, Tribble, Curtis G, Kron, Irving L

“…Background. Reperfusion injury after pulmonary transplantation can contribute significantly to postoperative pulmonary dysfunction. We hypothesized that…”
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On-line intraoperative quantitation of regional myocardial perfusion during coronary artery bypass graft operations with myocardial contrast two-dimensional echocardiography by Villanueva, F S, Spotnitz, W D, Jayaweera, A R, Dent, J, Gimple, L W, Kaul, S

“…We hypothesized that the success of coronary artery bypass graft operations could be assessed by means of on-line quantitative myocardial contrast…”
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Deoxygenated blood minimizes adherence of sonicated albumin microbubbles during cardioplegic arrest and after blood reperfusion: Experimental and clinical observations with myocardial contrast echocardiography by Bayfield, Matthew S., Lindner, Jonathan R., Kaul, Sanjiv, Ismail, Suad, Sheil, Meredith L.K., Goodman, N.Craig, Zacour, Richard, Spotnitz, William D.

“…Both administration of cardioplegic solution and blood reperfusion result in endothelial dysfunction. The transit rate of albumin microbubbles during…”
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Successful preoperative diagnosis and treatment of a saphenous vein coronary artery bypass graft aneurysm by Wyatt, D A, Gay, S B, Gimple, L W, Spotnitz, W D

“…A 71-year-old man who underwent a coronary artery bypass using a saphenous vein bypass graft (SVG) in 1977 presented with a new mediastinal mass on chest…”
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New insights into the physiology of retrograde cardioplegia delivery by Villanueva, F S, Spotnitz, W D, Glasheen, W P, Watson, D D, Jayaweera, A R, Kaul, S

“…Although retrograde cardioplegia (RC) is being increasingly used in clinical practice, its physiology is unclear. Because the microvascular architecture of the…”
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Acute thrombogenic effects of fibrin sealant on microvascular anastomoses in a rat model by Marek, C A, Amiss, Jr, L R, Morgan, R F, Spotnitz, W D, Drake, D B

“…Topically applied bioadhesives and hemostatic agents have gained wide acceptance in various surgical endeavors. However, the effect of thrombin-based fibrin…”
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Thrombogenic effects of a nonthrombin-based fibrin sealant compared with thrombin-based fibrin sealant on microvenous anastomoses in a rat model by Drake, D B, Faulkner, B C, Amiss, Jr, L R, Spotnitz, W D, Morgan, R F

“…The efficacy and safety of tissue adhesives needs to be clearly defined. A thrombin-based preparation of fibrin sealant has recently been shown to have…”
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Effect of Fibrinogen and Thrombin Concentrations on Mastectomy Seroma Prevention by Sanders, Robert P., Goodman, Norman C., Amiss, Jr, Lester R., Pierce, Richard A., Moore, Marcia M., Marx, Gerard, Morgan, Raymond F., Spotnitz, William D.

“…Seroma formation remains a significant clinical problem which increases morbidity and hospital costs in patients undergoing mastectomy operations. This study…”
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Fibrin sealant reduces the duration and amount of fluid drainage after axillary dissection : A randomized prospective clinical trial by MOORE, Marcia, BURAK, William E, NELSON, Edward, KEARNEY, Thomas, SIMMONS, Rache, MAYERS, Lynne, SPOTNITZ, William D

“…Patients who have axillary dissections during lumpectomy or modified radical mastectomy for breast carcinoma accumulate serosanguinous fluid, potentially…”
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Thoracoscopy in the subacute management of patients with thoracoabdominal trauma by Kern, J A, Tribble, C G, Spotnitz, W D, Rodgers, B M, Daniel, T M

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Fibrin glue application through the flexible fiberoptic bronchoscope: closure of bronchopleural fistulas by Glover, W, Chavis, T V, Daniel, T M, Kron, I L, Spotnitz, W D

“…Closure of bronchopleural fistulas can be accomplished by applying fibrin glue through a flexible fiberoptic bronchoscope. The advantages of this method…”
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