Search Results - "Spognardi, Anna"

Procedural and Anatomical Determinants of Multielectrode Renal Denervation Efficacy: Insights From Preclinical Models by Tzafriri, Abraham R, Mahfoud, Felix, Keating, John H, Spognardi, Anna-Maria, Markham, Peter M, Wong, Gee, Highsmith, Debby, O’Fallon, Patrick, Fuimaono, Kristine, Edelman, Elazer R

“…Radiofrequency renal denervation is under investigation for treatment of hypertension with variable success. We developed preclinical models to examine the…”
Get full text

Innervation Patterns May Limit Response to Endovascular Renal Denervation by Tzafriri, Abraham R., PhD, Mahfoud, Felix, MD, Keating, John H., DVM, DACVP, Markham, Peter M., MS, Spognardi, Anna, BA, Wong, Gee, BS, HT, Fuimaono, Kristine, BS, Böhm, Michael, MD, Edelman, Elazer R., MD, PhD

“…Abstract Background Renal denervation is a new interventional approach to treat hypertension with variable results. Objectives The purpose of this study was to…”
Get full text

Arterial microanatomy determines the success of energy-based renal denervation in controlling hypertension by Tzafriri, Abraham R, Keating, John H, Markham, Peter M, Spognardi, Anna-Maria, Stanley, James R L, Wong, Gee, Zani, Brett G, Highsmith, Debby, O'Fallon, Patrick, Fuimaono, Kristine, Mahfoud, Felix, Edelman, Elazer R

“…Renal denervation (RDN) is a treatment option for patients with hypertension resistant to conventional therapy. Clinical trials have demonstrated variable…”
Get more information

TCT-81 Quantification of Procedural and Anatomical Determinants of Multielectrode Renal Denervation by Tzafriri, Abraham, Mahfoud, Felix, Parikh, Sahil A., Keating, John, Spognardi, Anna-Maria, Markham, Peter, Edelman, Elazer

Get full text

Comparison of Renal Artery, Soft Tissue, and Nerve Damage After Irrigated Versus Nonirrigated Radiofrequency Ablation by Sakakura, Kenichi, Ladich, Elena, Fuimaono, Kristine, Grunewald, Debby, O’Fallon, Patrick, Spognardi, Anna-Maria, Markham, Peter, Otsuka, Fumiyuki, Yahagi, Kazuyuki, Shen, Kai, Kolodgie, Frank D, Joner, Michael, Virmani, Renu

“…BACKGROUND—The long-term efficacy of radiofrequency ablation of renal autonomic nerves has been proven in nonrandomized studies. However, long-term safety of…”
Get full text

Serial Evaluation of Vascular Response After Implantation of a New Sirolimus-Eluting Stent With Bioabsorbable Polymer (MISTENT): an optical coherence tomography and histopathological study by Attizzani, Guilherme F, Bezerra, Hiram G, Chamié, Daniel, Fujino, Yusuke, Spognardi, Anna-Maria, Stanley, James R L, Yamamoto, Hirosada, Mehanna, Emile, Wang, Wei, Carlyle, Wenda C, McClain, James B, Costa, Marco A

“…Novel vascular scaffolds aim at equipoise between safety and efficacy. Intravascular optical coherence tomography (OCT) allows in-vivo serial assessment of…”
Get more information

T-helper 2 cells are essential for modulation of vascular repair by allogeneic endothelial cells by Methe, Heiko, MD, Nanasato, Mamoru, MD, Spognardi, Anna-Maria, Groothuis, Adam, MS, Edelman, Elazer R., MD, PhD

“…Background Endothelial cells (ECs) embedded within 3-dimensional matrices (MEEC) control lumenal inflammation and intimal hyperplasia when placed in the…”
Get full text

TCT-432 Imaging-Based Evaluation and Differentiation of Vessel Preparation Technologies in a Porcine Model of Peripheral Artery Stenosis by Tzafriri, Abraham, Budrewicz, Jay, Spognardi, Anna, Secemsky, Eric

Get full text

Balloon-based drug coating delivery to the artery wall is dictated by coating micro-morphology and angioplasty pressure gradients by Tzafriri, Abraham R., Muraj, Benny, Garcia-Polite, Fernando, Salazar-Martín, Antonio G., Markham, Peter, Zani, Brett, Spognardi, Anna, Albaghdadi, Mazen, Alston, Steve, Edelman, Elazer R.

“…Paclitaxel coated balloon catheters (PCB) were developed as a polymer-free non-implantable alternative to drug eluting stents, delivering similar drug payloads…”
Get full text

Steady Flow Left Ventricle Unloading Is Superior to Pulsatile Pressure Augmentation Venting During Venoarterial Extracorporeal Membrane Oxygenation Support by Goffer, Efrat M, Lamberti, Kimberly K, Spognardi, Anna-Maria, Edelman, Elazer R, Keller, Steven P

“…Venoarterial extracorporeal membrane oxygenation (VA-ECMO) shunts venous blood to the systemic arterial circulation to provide end-organ perfusion while…”
Get full text

TCT-563 Superior and proximal nerves in porcine renal arteries are least accessible to radiofrequency ablation due to shielding by peri-arterial blood vessels and lymph nodes by Tzafriri, Abraham, Gacia-Polite, Fernando, Keating, John, Spognardi, Anna, Markham, Peter, Edelman, Elazer

Get full text

TCT CONNECT-371 Drug-Coated Balloon Contact Pressure Predicts Endoluminal Coating Distribution by Tzafriri, Abraham, Muraj, Benny, Gacia-Polite, Fernando, Salazar-Martin, Antonio-Gabino, Markham, Peter, Spognardi, Anna-Maria, Zani, Brett, Albaghdadi, Mazen, Alston, Steve, Edelman, Elazer

Get full text

TCT-561 Splenic Artery Denervation: Rationale, Feasibility, and Early Pre-Clinical Experience in a Porcine Model of Inflammatory Arthritis by Albaghdadi, Mazen, Gacia-Polite, Fernando, Zani, Brett, Keating, John, Melidone, Raffaele, Spognardi, Anna, Markham, Peter, Tzafriri, Abraham

Get full text

Splenic artery denervation: target micro-anatomy, feasibility, and early preclinical experience by Albaghdadi, Mazen, Garcia-Polite, Fernando, Zani, Brett, Keating, John, Melidone, Raffaele, Spognardi, Anna, Markham, Peter, Tzafriri, Abraham

“…This study sought to evaluate perisplenic artery nerve distribution and the feasibility of splenic artery denervation (SDN). The NEXION radiofrequency catheter…”
Get full text

Procedural and anatomical determinants of multi-electrode renal denervation efficacy – insights from preclinical models by Tzafriri, Abraham R., Mahfoud, Felix, Keating, John H., Spognardi, Anna-Maria, Markham, Peter M., Wong, Gee, Highsmith, Debby, O’Fallon, Patrick, Fuimaono, Kristine, Edelman, Elazer R.

“…Radiofrequency renal denervation (RDN) is under investigation for treatment of hypertension with variable success. We developed preclinical models to examine…”
Get full text

CRT-200.08 Six-Month Safety Evaluation of the Chocolate Touch™ Drug-Coated Balloon Catheter in the Swine Peripheral Artery Model by Tzafriri, Abraham R., Spognardi, Anna Maria, Bailey, Lynn, Keating, John, Markham, Peter, Binyamin, Gary, Pizarro, Maria, Konstantino, Eitan, Edelman, Elazer R.

Get full text

TCT-402Renal Norepinephrine Reduction Following Radiofrequency Renal Denervation Correlates with Extent of Nerve Ablation: Roles of Ablation Areas, Anatomy, and Number of Treatments by Tzafriri, Abraham R, Mahfoud, Felix, Keating, John, Wong, Gee, Spognardi, Anna-Maria, Stanley, James, Highsmith, Debby, O'Fallon, Patrick, Edelman, Elazer

“…Average %AN increased with total ablation area as predicted by the computational model when accounting for the (average) measured non-uniform radial nerve…”
Get full text

TCT- 402 Renal Norepinephrine Reduction Following Radiofrequency Renal Denervation Correlates with Extent of Nerve Ablation: Roles of Ablation Areas, Anatomy, and Number of Treatments by Tzafriri, Abraham R, Mahfoud, Felix, Keating, John, Wong, Gee, Spognardi, Anna-Maria, Stanley, James, Highsmith, Debby, O'Fallon, Patrick, Edelman, Elazer

Get full text

TCT-425 Innervation Patterns in the Renal Artery Ostium May Limit the Efficacy of Endovascular Radiofrequency Ablation by Tzafriri, Abraham R, Mahfoud, Felix, Keating, John, Markham, Peter, Spognardi, Anna-Maria, Wong, Gee, Fuimaono, Kristine, Edelman, Elazer

“…Conclusions Renal denervation therapies which specifically target the renal ostium must account for the unique anatomy and treatments localized to the superior…”
Get full text

TCT-552 Particulates from Hydrophilic Coated Guiding Sheaths Embolize to the Brain by Stanley, James, Regan, Kathryn, LaRochelle, Alan, Zani, Brett, Markham, Peter, Bailey, Lynn, Spognardi, Anna-Maria, Wong, Gee, Tzafriri, Abraham R, Kopia, Gregory A, Edelman, Elazer

“…Results The Cook guiding sheath was associated with intravascular accumulation of an amorphous, non-refractile, non-crystalline, and non-birefringent embolic…”
Get full text