Search Results - "Spitzer, W"

A jsPsych touchscreen extension for behavioral research on touch-enabled interfaces by Strittmatter, Younes, Spitzer, Markus W. H., Ging-Jehli, Nadja, Musslick, Sebastian

“…Online experiments are increasingly gaining traction in the behavioral sciences. Despite this, behavioral researchers have largely continued to use keyboards…”
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Coupled Ca2+/H+ transport by cytoplasmic buffers regulates local Ca2+ and H+ ion signaling by Swietach, Pawel, Youm, Jae-Boum, Saegusa, Noriko, Leem, Chae-Hun, Spitzer, Kenneth W, Vaughan-Jones, Richard D

“…Ca(2+) signaling regulates cell function. This is subject to modulation by H(+) ions that are universal end-products of metabolism. Due to slow diffusion and…”
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Na⁺ ions as spatial intracellular messengers for co-ordinating Ca²⁺ signals during pH heterogeneity in cardiomyocytes by Swietach, Pawel, Spitzer, Kenneth W, Vaughan-Jones, Richard D

“…Contraction of the heart is regulated by electrically evoked Ca(2+) transients (CaTs). H(+) ions, the end products of metabolism, modulate CaTs through direct…”
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Genetic determinants of cardiometabolic and pulmonary phenotypes and obstructive sleep apnoea in HCHS/SOL by Zhang, Yuan, Elgart, Michael, Kurniansyah, Nuzulul, Spitzer, Brian W., Wang, Heming, Kim, Doyoon, Shah, Neomi, Daviglus, Martha, Zee, Phyllis C., Cai, Jianwen, Gottlieb, Daniel J., Cade, Brian E., Redline, Susan, Sofer, Tamar

“…Obstructive Sleep Apnoea (OSA) often co-occurs with cardiometabolic and pulmonary diseases. This study is to apply genetic analysis methods to explain the…”
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Blockade of CaMKII depresses conduction preferentially in the right ventricular outflow tract and promotes ischemic ventricular fibrillation in the rabbit heart by Warren, Mark, Sciuto, Katie J, Taylor, Tyson G, Garg, Vivek, Torres, Natalia S, Shibayama, Junko, Spitzer, Kenneth W, Zaitsev, Alexey V

“…Calcium/calmodulin-dependent protein kinase II (CaMKII) regulates the principle ion channels mediating cardiac excitability and conduction, but how this…”
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Pumping Ca2+ up H+ gradients: a Ca2+–H+ exchanger without a membrane by Swietach, Pawel, Leem, Chae‐Hun, Spitzer, Kenneth W., Vaughan‐Jones, Richard D.

“…Cellular processes are exquisitely sensitive to H+ and Ca2+ ions because of powerful ionic interactions with proteins. By regulating the spatial and temporal…”
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Ca2+-mobility in the sarcoplasmic reticulum of ventricular myocytes is low by Swietach, Pawel, Spitzer, Kenneth W, Vaughan-Jones, Richard D

“…The sarcoplasmic reticulum (SR) in ventricular myocytes contains releasable Ca(2+) for activating cellular contraction. Recent measurements of intra-SR…”
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Functional and Pharmacological Analysis of Cardiomyocytes Differentiated from Human Peripheral Blood Mononuclear-Derived Pluripotent Stem Cells by Riedel, Michael, Jou, Chuanchau J., Lai, Shuping, Lux, Robert L., Moreno, Alonso P., Spitzer, Kenneth W., Christians, Elizabeth, Tristani-Firouzi, Martin, Benjamin, Ivor J.

“…Advances in induced pluripotent stem cell (iPSC) technology have set the stage for routine derivation of patient- and disease-specific human iPSC-cardiomyocyte…”
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Prediction of auditory spatial acuity from neural images on the owl's auditory space map by Bala, Avinash D. S, Spitzer, Matthew. W, Takahashi, Terry T

“…The owl can discriminate changes in the location of sound sources as small as 3° and can aim its head to within 2° of a source. A typical neuron in its…”
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Anatomical and physiological definition of the motor cortex of the marmoset monkey by Burman, Kathleen J., Palmer, Susan M., Gamberini, Michela, Spitzer, Matthew W., Rosa, Marcello G.P.

“…We used a combination of anatomical and physiological techniques to define the primary motor cortex (M1) of the marmoset monkey and its relationship to…”
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Mutation of Gtf2ird1 from the Williams–Beuren syndrome critical region results in facial dysplasia, motor dysfunction, and altered vocalisations by Howard, Monique L, Palmer, Stephen J, Taylor, Kylie M, Arthurson, Geoffrey J, Spitzer, Matthew W, Du, Xin, Pang, Terence Y.C, Renoir, Thibault, Hardeman, Edna C, Hannan, Anthony J

“…Abstract Insufficiency of the transcriptional regulator GTF2IRD1 has become a strong potential explanation for some of the major characteristic features of the…”
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Connections of the marmoset rostrotemporal auditory area: express pathways for analysis of affective content in hearing by Reser, David H., Burman, Kathleen J., Richardson, Karyn E., Spitzer, Matthew W., Rosa, Marcello G.P.

“…The current hierarchical model of primate auditory cortical processing proposes a core of ‘primary‐like’ areas, which is surrounded by secondary (belt) and…”
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Beat-to-beat repolarization variability in ventricular myocytes and its suppression by electrical coupling by Zaniboni, M, Pollard, A E, Yang, L, Spitzer, K W

“…Single ventricular myocytes paced at a constant rate and held at a constant temperature exhibit beat-to-beat variations in action potential duration (APD). In…”
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Metabolic determinants of electrical failure in ex-vivo canine model of cardiac arrest: evidence for the protective role of inorganic pyrophosphate by Shibayama, Junko, Taylor, Tyson G, Venable, Paul W, Rhodes, Nathaniel L, Gil, Ryan B, Warren, Mark, Wende, Adam R, Abel, E Dale, Cox, James, Spitzer, Kenneth W, Zaitsev, Alexey V

“…Deterioration of ventricular fibrillation (VF) into asystole or severe bradycardia (electrical failure) heralds a fatal outcome of cardiac arrest. The role of…”
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Third generation oral contraceptives and risk of venous thromboembolic disorders: an international case-control study by Spitzer, Walter O, Lewis, Michael A, Heinemann, Lothar A J, Thorogood, Margaret

“…Abstract Objective: To test whether use of combined oral contraceptives containing third generation progestogens is associated with altered risk of venous…”
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Mechanical modulation of the transverse tubular system of ventricular cardiomyocytes by McNary, Thomas G., Spitzer, Kenneth W., Holloway, Hilary, Bridge, John H.B., Kohl, Peter, Sachse, Frank B.

“…In most mammalian cardiomyocytes, the transverse tubular system (t-system) is a major site for electrical signaling and excitation–contraction coupling. The…”
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Intrinsic H+ ion mobility in the rabbit ventricular myocyte by Vaughan‐Jones, R. D., Peercy, B. E., Spitzer, K. W.

“…The intrinsic mobility of intracellular H + ions was investigated by confocally imaging the longitudinal movement of acid inside rabbit ventricular myocytes…”
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Platelet-activating factor stimulates sodium-hydrogen exchange in ventricular myocytes by Ajiro, Yoichi, Saegusa, Noriko, Giles, Wayne R, Stafforini, Diana M, Spitzer, Kenneth W

“…Sodium-hydrogen exchanger (NHE), the principal sarcolemmal acid extruder in ventricular myocytes, is stimulated by a variety of autocrine/paracrine factors and…”
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Enhanced activity of ventricular Na+-HCO3- cotransport in pressure overload hypertrophy by Yamamoto, Taku, Shirayama, Takeshi, Sakatani, Tomohiko, Takahashi, Tomosaburo, Tanaka, Hideo, Takamatsu, Tetsuro, Spitzer, Kenneth W, Matsubara, Hiroaki

“…The Na(+)-HCO(3)(-) cotransporter (NBC) plays a key role in intracellular pH (pH(i)) regulation in normal ventricular muscle. However, the state of NBC in…”
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Location of the initiation site of calcium transients and sparks in rabbit heart Purkinje cells by Cordeiro, J. M., Spitzer, K. W., Giles, W. R., Ershler, P. E., Cannell, M. B., Bridge, J. H. B.

“…The distribution and localization of Ca 2+ transients and Ca 2+ sparks in isolated adult rabbit Purkinje cells were examined using confocal microscopy and the…”
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