Search Results - "Spitzer, Sonia"

Phenotypic characterization of retinoic acid differentiated SH-SY5Y cells by transcriptional profiling by Korecka, Joanna A, van Kesteren, Ronald E, Blaas, Eva, Spitzer, Sonia O, Kamstra, Jorke H, Smit, August B, Swaab, Dick F, Verhaagen, Joost, Bossers, Koen

“…Multiple genetic and environmental factors play a role in the development and progression of Parkinson's disease (PD). The main neuropathological hallmark of…”
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Developmental Signatures of Microbiota-Derived Metabolites in the Mouse Brain by Swann, Jonathan R, Spitzer, Sonia O, Diaz Heijtz, Rochellys

“…The gut microbiome is recognized to exert a wide-ranging influence on host health and disease, including brain development and behavior. Commensal bacteria can…”
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Gene Editing in Rat Embryonic Stem Cells to Produce In Vitro Models and In Vivo Reporters by Chen, Yaoyao, Spitzer, Sonia, Agathou, Sylvia, Karadottir, Ragnhildur Thora, Smith, Austin

“…Rat embryonic stem cells (ESCs) offer the potential for sophisticated genome engineering in this valuable biomedical model species. However, germline…”
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Postnatal prebiotic supplementation in rats affects adult anxious behaviour, hippocampus, electrophysiology, metabolomics, and gut microbiota by Spitzer, Sonia O., Tkacz, Andrzej, Savignac, Helene M., Cooper, Matthew, Giallourou, Natasa, Mann, Edward O., Bannerman, David M., Swann, Jonathan R., Anthony, Daniel C., Poole, Philip S., Burnet, Philip W.J.

“…We have shown previously that prebiotic (Bimuno galacto-oligosacharides, B-GOS®) administration to neonatal rats increased hippocampal NMDAR proteins. The…”
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Clemastine and metformin extend the window of NMDA receptor surface expression in ageing oligodendrocyte precursor cells by Kamen, Yasmine, Evans, Kimberley Anne, Sitnikov, Sergey, Spitzer, Sonia Olivia, de Faria, Omar, Yucel, Mert, Káradóttir, Ragnhildur Thóra

“…In the central nervous system, oligodendrocyte precursor cells (OPCs) proliferate and differentiate into myelinating oligodendrocytes throughout life, allowing…”
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Heterogeneity in oligodendrocyte precursor cell proliferation is dynamic and driven by passive bioelectrical properties by Pivoňková, Helena, Sitnikov, Sergey, Kamen, Yasmine, Vanhaesebrouck, An, Matthey, Moritz, Spitzer, Sonia Olivia, Ng, Yan Ting, Tao, Chenyue, de Faria, Omar, Varga, Balazs Viktor, Káradóttir, Ragnhildur Thóra

“…Oligodendrocyte precursor cells (OPCs) generate myelinating oligodendrocytes and are the main proliferative cells in the adult central nervous system. OPCs are…”
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A neuronal PI(3,4,5)P3-dependent program of oligodendrocyte precursor recruitment and myelination by Goebbels, Sandra, Wieser, Georg L, Pieper, Alexander, Spitzer, Sonia, Weege, Bettina, Yan, Kuo, Edgar, Julia M, Yagensky, Oleksandr, Wichert, Sven P, Agarwal, Amit, Karram, Khalad, Renier, Nicolas, Tessier-Lavigne, Marc, Rossner, Moritz J, Káradóttir, Ragnhildur Thóra, Nave, Klaus-Armin

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Oligodendrocyte Progenitor Cells Become Regionally Diverse and Heterogeneous with Age by Spitzer, Sonia Olivia, Sitnikov, Sergey, Kamen, Yasmine, Evans, Kimberley Anne, Kronenberg-Versteeg, Deborah, Dietmann, Sabine, de Faria, Omar, Agathou, Sylvia, Káradóttir, Ragnhildur Thóra

“…Oligodendrocyte progenitor cells (OPCs), which differentiate into myelinating oligodendrocytes during CNS development, are the main proliferative cells in the…”
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Glutamate signalling: A multifaceted modulator of oligodendrocyte lineage cells in health and disease by Spitzer, Sonia, Volbracht, Katrin, Lundgaard, Iben, Káradóttir, Ragnhildur T.

“…Myelin is essential for the mammalian brain to function efficiently. Whilst many factors have been associated with regulating the differentiation of…”
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A neuronal PI(3,4,5)P 3 -dependent program of oligodendrocyte precursor recruitment and myelination by Goebbels, Sandra, Wieser, Georg L, Pieper, Alexander, Spitzer, Sonia, Weege, Bettina, Yan, Kuo, Edgar, Julia M, Yagensky, Oleksandr, Wichert, Sven P, Agarwal, Amit, Karram, Khalad, Renier, Nicolas, Tessier-Lavigne, Marc, Rossner, Moritz J, Káradóttir, Ragnhildur Thóra, Nave, Klaus-Armin

“…The molecular trigger of CNS myelination is unknown. By targeting Pten in cerebellar granule cells and activating the AKT1-mTOR pathway, we increased the…”
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Prebiotic attenuation of olanzapine-induced weight gain in rats: analysis of central and peripheral biomarkers and gut microbiota by Kao, Amy Chia-Ching, Spitzer, Sonia, Anthony, Daniel C., Lennox, Belinda, Burnet, Philip W. J.

“…Olanzapine is an effective antipsychotic drug but since it causes significant weight gain, it is not well tolerated by psychosis patients. The prebiotic, B-GOS…”
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High Yields of Oligodendrocyte Lineage Cells from Human Embryonic Stem Cells at Physiological Oxygen Tensions for Evaluation of Translational Biology by Stacpoole, Sybil R.L., Spitzer, Sonia, Bilican, Bilada, Compston, Alastair, Karadottir, Ragnhildur, Chandran, Siddharthan, Franklin, Robin J.M.

“…We have established and efficient system to specify NG2/PDGF-Rα/OLIG2+ oligodendrocyte precursor cells (OPCs) from human embryonic stem cells (hESCs) at low,…”
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Stem cells expanded from the human embryonic hindbrain stably retain regional specification and high neurogenic potency by Tailor, Jignesh, Kittappa, Raja, Leto, Ketty, Gates, Monte, Borel, Melodie, Paulsen, Ole, Spitzer, Sonia, Karadottir, Ragnhildur Thora, Rossi, Ferdinando, Falk, Anna, Smith, Austin

“…Stem cell lines that faithfully maintain the regional identity and developmental potency of progenitors in the human brain would create new opportunities in…”
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FUNCTIONAL HUMAN ES-DERIVED OPCS AT LOW OXYGEN by Stacpoole, Sybil, Spitzer, Sonia, Bilican, Bilada, Compston, Alastair, Karadottir, Ragnhildur, Chandran, Siddharthan, Franklin, Robin

“…We have established an efficient system to specify NG2/PDGF-R alpha /OLIG2+ oligodendrocyte precursor cells (OPCs) from human embryonic stem cells (hESCs) at…”
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A neuronal PIP3-dependent program of oligodendrocyte precursor recruitment and myelination by Goebbels, Sandra, Wieser, Georg L, Pieper, Alexander, Spitzer, Sonia, Weege, Bettina, Yan, Kuo, Edgar, Julia M, Yagensky, Oleksandr, Wichert, Sven P, Agarwal, Amit, Karram, Khalad, Renier, Nicolas, Tessier-Lavigne, Marc, Rossner, Moritz J, Káradóttir, Ragnhildur Thóra, Nave, Klaus-Armin

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A neuronal PI(3,4,5)P sub(3)-dependent program of oligodendrocyte precursor recruitment and myelination by Goebbels, Sandra, Wieser, Georg L, Pieper, Alexander, Spitzer, Sonia, Weege, Bettina, Yan, Kuo, Edgar, Julia M, Yagensky, Oleksandr, Wichert, Sven P, Agarwal, Amit, Karram, Khalad, Renier, Nicolas, Tessier-Lavigne, Marc, Rossner, Moritz J, Karadottir, Ragnhildur Thora, Nave, Klaus-Armin

“…The molecular trigger of CNS myelination is unknown. By targeting Pten in cerebellar granule cells and activating the AKT1-mTOR pathway, we increased the…”
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A neuronal PI(3,4,5)P3-dependent program of oligodendrocyte precursor recruitment and myelination by Goebbels, Sandra, Wieser, Georg L, Pieper, Alexander, Spitzer, Sonia, Weege, Bettina, Yan, Kuo, Edgar, Julia M, Yagensky, Oleksandr, Wichert, Sven P, Agarwal, Amit, Karram, Khalad, Renier, Nicolas, Tessier-Lavigne, Marc, Rossner, Moritz J, Káradóttir, Ragnhildur Thóra, Nave, Klaus-Armin

“…In the CNS, the primary signal initiating myelination and its cellular origin remain unclear. Goebbels et al . find that deleting PTEN from cerebellar granule…”
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Clever glia by Spitzer, Sonia, Agathou, Sylvia, Karadottir, Ragnhildur

“…Twenty years ago glial cells were shown to contribute to neuronal information processing, instead of merely supporting neuronal function, thus challenging the…”
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