Search Results - "Spitzer, C"

Electrical activity in early neuronal development by Spitzer, Nicholas C

“…The construction of the brain during embryonic development was thought to be largely independent of its electrical activity. In this view, proliferation,…”
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Neurotransmitter Switching? No Surprise by Spitzer, Nicholas C.

“…Among the many forms of brain plasticity, changes in synaptic strength and changes in synapse number are particularly prominent. However, evidence for…”
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Neurotransmitter Switching in the Adult Brain Regulates Behavior by Dulcis, Davide, Jamshidi, Pouya, Leutgeb, Stefan, Spitzer, Nicholas C.

“…Neurotransmitters have been thought to be fixed throughout life, but whether sensory stimuli alter be h a vio rally relevant transmitter expression in the…”
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Exercise enhances motor skill learning by neurotransmitter switching in the adult midbrain by Li, Hui-quan, Spitzer, Nicholas C.

“…Physical exercise promotes motor skill learning in normal individuals and those with neurological disorders but its mechanism of action is unclear. We find…”
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Calcium signaling in neuronal development by Rosenberg, Sheila S, Spitzer, Nicholas C

“…The development of the nervous system involves the generation of a stunningly diverse array of neuronal subtypes that enable complex information processing and…”
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Psychopathology, disordered eating, and impulsivity as predictors of outcomes of bariatric surgery by Sarwer, David B., Allison, Kelly C., Wadden, Thomas A., Ashare, Rebecca, Spitzer, Jacqueline C., McCuen-Wurst, Courtney, LaGrotte, Caitlin, Williams, Noel N., Edwards, Michael, Tewksbury, Colleen, Wu, Jingwei

“…•Mood and substance use disorders (SUDs), as well as BED, share common features of impulsivity.•Impulse control is a central factor in eating behavior and…”
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Activity-Dependent Expression of Lmx1b Regulates Specification of Serotonergic Neurons Modulating Swimming Behavior by Demarque, Michaël, Spitzer, Nicholas C.

“…Genetic programs, environmental factors, and electrical activity interact to drive the maturation of the brain. Although the cascade of transcription factors…”
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Neuronal activity regulates neurotransmitter switching in the adult brain following light-induced stress by Meng, Da, Li, Hui-quan, Deisseroth, Karl, Leutgeb, Stefan, Spitzer, Nicholas C.

“…Neurotransmitter switching in the adult mammalian brain occurs following photoperiod-induced stress, but the mechanism of regulation is unknown. Here, we…”
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A flagellate-to-amoeboid switch in the closest living relatives of animals by Brunet, Thibaut, Albert, Marvin, Roman, William, Coyle, Maxwell C, Spitzer, Danielle C, King, Nicole

“…Amoeboid cell types are fundamental to animal biology and broadly distributed across animal diversity, but their evolutionary origin is unclear. The closest…”
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Non-Cell-Autonomous Mechanism of Activity-Dependent Neurotransmitter Switching by Guemez-Gamboa, Alicia, Xu, Lin, Meng, Da, Spitzer, Nicholas C.

“…Activity-dependent neurotransmitter switching engages genetic programs regulating transmitter synthesis, but the mechanism by which activity is transduced is…”
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Spatial and temporal second messenger codes for growth cone turning by Nicol, Xavier, Hong, Kwan Pyo, Spitzer, Nicholas C

“…Cyclic AMP (cAMP) and calcium are ubiquitous, interdependent second messengers that regulate a wide range of cellular processes. During development of neuronal…”
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Drug-induced change in transmitter identity is a shared mechanism generating cognitive deficits by Pratelli, Marta, Hakimi, Anna M., Thaker, Arth, Jang, Hyeonseok, Li, Hui-quan, Godavarthi, Swetha K., Lim, Byung Kook, Spitzer, Nicholas C.

“…Cognitive deficits are long-lasting consequences of drug use, yet the convergent mechanism by which classes of drugs with different pharmacological properties…”
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The psychosocial burden of visible disfigurement following traumatic injury by Sarwer, David B., Siminoff, Laura A., Gardiner, Heather M., Spitzer, Jacqueline C.

“…Hundreds of thousands of individuals experience traumatic injuries each year. Some are mild to moderate in nature and patients experience full functional…”
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Breast cancer cell-secreted miR-199b-5p hijacks neurometabolic coupling to promote brain metastasis by Ruan, Xianhui, Yan, Wei, Cao, Minghui, Daza, Ray Anthony M., Fong, Miranda Y., Yang, Kaifu, Wu, Jun, Liu, Xuxiang, Palomares, Melanie, Wu, Xiwei, Li, Arthur, Chen, Yuan, Jandial, Rahul, Spitzer, Nicholas C., Hevner, Robert F., Wang, Shizhen Emily

“…Breast cancer metastasis to the brain is a clinical challenge rising in prevalence. However, the underlying mechanisms, especially how cancer cells adapt a…”
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Differences in Number of Midbrain Dopamine Neurons Associated with Summer and Winter Photoperiods in Humans by Aumann, Tim D, Raabus, Mai, Tomas, Doris, Prijanto, Agustinus, Churilov, Leonid, Spitzer, Nicholas C, Horne, Malcolm K

“…Recent evidence indicates the number of dopaminergic neurons in the adult rodent hypothalamus and midbrain is regulated by environmental cues, including…”
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Activity-dependent competition regulates motor neuron axon pathfinding via PlexinA3 by Plazas, Paola V., Nicol, Xavier, Spitzer, Nicholas C.

“…The role of electrical activity in axon guidance has been extensively studied in vitro. To better understand its role in the intact nervous system, we imaged…”
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cJun integrates calcium activity and tlx3 expression to regulate neurotransmitter specification by Spitzer, Nicholas C, Marek, Kurt W, Kurtz, Lisa M

“…Building on their previous observation that neuronal calcium spike activity can drive neurotransmitter specification during development, these authors report…”
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In vivo regulation of axon extension and pathfinding by growth-cone calcium transients by Gomez, Timothy M, Spitzer, Nicholas C

“…Growth cones at the tips of extending neurites migrate through complex environments in the developing nervous system and guide axons to appropriate target…”
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AGS3 antagonizes LGN to balance oriented cell divisions and cell fate choices in mammalian epidermis by Descovich, Carlos P, Lough, Kendall J, Jena, Akankshya, Wu, Jessica J, Yom, Jina, Spitzer, Danielle C, Uppalapati, Manuela, Kedziora, Katarzyna M, Williams, Scott E

“…Oriented cell divisions balance self-renewal and differentiation in stratified epithelia such as the skin epidermis. During peak epidermal stratification, the…”
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Activity-dependent homeostatic specification of transmitter expression in embryonic neurons by Borodinsky, Laura N, Root, Cory M, Cronin, Julia A, Sann, Sharon B, Gu, Xiaonan, Spitzer, Nicholas C

“…Neurotransmitters are essential for interneuronal signalling, and the specification of appropriate transmitters in differentiating neurons has been related to…”
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