Search Results - "Spithill, T.W."

Comparative kinetics of serological and coproantigen ELISA and faecal egg count in cattle experimentally infected with Fasciola hepatica and following treatment with triclabendazole by Brockwell, Y.M., Spithill, T.W., Anderson, G.R., Grillo, V., Sangster, N.C.

“…Three methods of diagnosing Fasciola hepatica (F. hepatica) infection (a coproantigen ELISA, Bio-X Diagnostics, Belgium, Faecal Egg Count (FEC), and a serum…”
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Evidence for high genetic diversity of NAD1 and COX1 mitochondrial haplotypes among triclabendazole resistant and susceptible populations and field isolates of Fasciola hepatica (liver fluke) in Australia by Elliott, T, Muller, A, Brockwell, Y, Murphy, N, Grillo, V, Toet, H M, Anderson, G, Sangster, N, Spithill, T W

“…In recent years, the global incidence of Fasciola hepatica (liver fluke) infections exhibiting resistance to triclabendazole (TCBZ) has increased, resulting in…”
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The sensitivity and specificity of two methods for detecting Fasciola infections in cattle by Anderson, N., Luong, T.T., Vo, N.G., Bui, K.L., Smooker, P.M., Spithill, T.W.

“…Counts of Fasciola spp. eggs in faeces and measurements of antibody concentration to the excretory/secretory antigens of Fasciola spp. by ELISA were related to…”
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Identification of two allelic forms of ovine CD4 exhibiting a Ser183/Pro183 polymorphism in the coding sequence of domain 3 by Boscariol, R, Pleasance, J, Piedrafita, D.M, Raadsma, H.W, Spithill, T.W

“…The ovine CD4 cDNA sequence from four sheep sources (Australian Merino, Indonesian Thin Tail, Canadian cross bred, Prealpes du sud) predicts a protein of 455…”
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High prevalence of fasciolosis and evaluation of drug efficacy against Fasciola hepatica in dairy cattle in the Maffra and Bairnsdale districts of Gippsland, Victoria, Australia by Elliott, T.P., Kelley, J.M., Rawlin, G., Spithill, T.W.

“…•81% mean prevalence of Fasciola in dairy cattle on 6/15 farms tested in Gippsland.•High correlation (R2=0.8849) between bulk and single coproantigen ELISA…”
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Resistance of Indonesian thin tail sheep against Fasciola gigantica and F. hepatica by Roberts, J.A., Estuningsih, E., Widjayanti, S., Wiedosari, E., Partoutomo, S., Spithill, T.W.

“…High resistance of Indonesian thin tail (ITT) sheep against Fasciola gigantica has been confirmed. Naive ITT sheep had only 17% of the number of mature…”
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The silencing of cysteine proteases in Fasciola hepatica newly excysted juveniles using RNA interference reduces gut penetration by McGonigle, Louise, Mousley, Angela, Marks, Nikki J., Brennan, Gerard P., Dalton, John P., Spithill, Terry W., Day, Tim A., Maule, Aaron G.

“…Probing protein function in parasitic flatworms is hampered by the difficulties associated with the development of transgenic approaches. Although RNA…”
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Host responses during experimental infection with Fasciola gigantica or Fasciola hepatica in Merino sheep. I. Comparative immunological and plasma biochemical changes during early infection by Raadsma, H.W, Kingsford, N.M, Suharyanta, Spithill, T.W, Piedrafita, D

“…This study reports the early biochemical changes in plasma, comparative host-immune responses and parasite recovery data in Merino sheep during the first 10…”
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Host responses during experimental infection with Fasciola gigantica and Fasciola hepatica in Merino sheep by Raadsma, H.W., Kingsford, N.M., Suharyanta, Spithill, T.W., Piedrafita, D.

“…This study reports on the predictive relationship between serological, immunological and pathological responses following experimental inoculation with…”
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Discovery and validation of serum biomarkers expressed over the first twelve weeks of Fasciola hepatica infection in sheep by Rioux, M.-C., Carmona, C., Acosta, D., Ward, B., Ndao, M., Gibbs, B.F., Bennett, H.P., Spithill, T.W.

“…Serum biomarkers associated with Fasciola hepatica infection of Corriedale sheep were analysed during the first 12 weeks of infection using surface-enhanced…”
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Host responses during experimental infection with Fasciola gigantica or Fasciola hepatica in Merino sheep by Raadsma, H.W., Kingsford, N.M., Suharyanta, Spithill, T.W., Piedrafita, D.

“…This study reports the early biochemical changes in plasma, comparative host-immune responses and parasite recovery data in Merino sheep during the first 10…”
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Host responses during experimental infection with Fasciola gigantica and Fasciola hepatica in Merino sheep : II. Development of a predictive index for Fasciola gigantica worm burden by Raadsma, H.W, Kingsford, N.M, Suharyanta, Spithill, T.W, Piedrafita, D

“…This study reports on the predictive relationship between serological, immunological and pathological responses following experimental inoculation with…”
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Vaccination with a Plasmodium chabaudi adami multivalent DNA vaccine cross-protects A/J mice against challenge with P. c. adami DK and virulent Plasmodium chabaudi chabaudi AS parasites by Scorza, T., Grubb, K., Cambos, M., Santamaria, C., Malu, D. Tshikudi, Spithill, T.W.

“…A current goal of malaria vaccine research is the development of vaccines that will cross-protect against multiple strains of malaria. In the present study,…”
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Identification of two allelic forms of ovine CD4 exhibiting a Ser 183/Pro 183 polymorphism in the coding sequence of domain 3 by Boscariol, R., Pleasance, J., Piedrafita, D.M., Raadsma, H.W., Spithill, T.W.

“…The ovine CD4 cDNA sequence from four sheep sources (Australian Merino, Indonesian Thin Tail, Canadian cross bred, Prealpes du sud) predicts a protein of 455…”
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Fasciola hepatica and Fasciola gigantica: Cloning and characterisation of 70 kDa heat-shock proteins reveals variation in HSP70 gene expression between parasite species recovered from sheep by Smith, Rebecca E., Spithill, Terry W., Pike, Robert N., Meeusen, Els N.T., Piedrafita, David

“…Fasciola hepatica and Fasciola gigantica are trematode parasites responsible for fasciolosis, a disease of ruminant animals which is also increasingly…”
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Liver fluke vaccines: Vaccination Against Fasciolosis by a Multivalent Vaccine of Recombinant Stage-Specific Antigens by Jayaraj, R., Piedrafita, D., Dynon, K., Grams, R., Spithill, T.W., Smooker, P.M.

“…Fasciola's excretory-secretory material comprises chiefly cathepsin B and cathepsin L. These cysteine proteases are proposed as major mediators of parasitism,…”
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Antibody‐dependent cell‐mediated cytotoxicity to newly excysted juvenile Fasciola hepatica in vitro is mediated by reactive nitrogen intermediates by Piedrafita, D., Parsons, J.C., Sandeman, R.M., Wood, P.R., Estuningsih, S.E., Partoutomo, S., Spithill, T.W.

“…Passive intraperitoneal transfer of sera from Fasciola hepatica‐infected sheep, cattle or rats can protect naive rats from F. hepatica infection, suggesting a…”
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The protective efficacy of MSP4/5 against lethal Plasmodium chabaudi adami challenge is dependent on the type of DNA vaccine vector and vaccination protocol by Rainczuk, A, Smooker, P.M, Kedzierski, L, Black, C.G, Coppel, R.L, Spithill, T.W

“…The enhancement of immunogenicity of malarial DNA vaccines is important if they are to have practical application in protecting against blood-stage malaria…”
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Characterisation of humoral immune responses in dogs vaccinated with irradiated Ancylostoma caninum by Boag, P.R, Parsons, J.C, Presidente, P.J.A, Spithill, T.W, Sexton, J.L

“…Infection with Ancylostoma caninum, an intestinal hookworm of dogs, can cause debilitating and potentially life-threatening disease. In the current study,…”
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Fasciola hepatica: Characterization and Cloning of the Major Cathepsin B Protease Secreted by Newly Excysted Juvenile Liver Fluke by Wilson, Lachlan R., Good, Robert T., Panaccio, Michael, Wijffels, Gene L., Sandeman, R.Mark, Spithill, Terry W.

“…Wilson, L. R., Good, R. T., Panaccio, M., Wijffels, G. L., Sandeman, R. M., and Spithill, T. W. 1998.Fasciola hepatica:Characterization and cloning of the…”
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