Search Results - "Spiropoulos, J."

Investigation into the Pathology of Idiopathic Systemic Amyloidosis in Four Captive Badgers (Meles meles) by Bianco, C., Sánchez-Cordón, P.J., Verin, R., Godinho, A., Weyer, U., Lesellier, S., Spiropoulos, J., Floyd, T., Everest, D., Núñez, A.

“…Systemic idiopathic amyloidosis was described in four captive badgers (Meles meles). Two animals (B1 and B2) were not enrolled in any trial, while animals B3…”
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Pathogenesis of experimental bovine spongiform encephalopathy: preclinical infectivity in tonsil and observations on the distribution of lingual tonsil in slaughtered cattle by Wells, G. A. H., Spiropoulos, J., Hawkins, S. A. C., Ryder, S. J.

“…The infectivity in tissues from cattle exposed orally to the agent of BSE was assayed by the intracerebral inoculation of cattle. In addition to the…”
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Does the Presence of Scrapie Affect the Ability of Current Statutory Discriminatory Tests To Detect the Presence of Bovine Spongiform Encephalopathy? by Simmons, M M, Chaplin, M J, Vickery, C M, Simon, S, Davis, L, Denyer, M, Lockey, R, Stack, M J, O'Connor, M J, Bishop, K, Gough, K C, Maddison, B C, Thorne, L, Spiropoulos, J

“…Current European Commission (EC) surveillance regulations require discriminatory testing of all transmissible spongiform encephalopathy (TSE)-positive small…”
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Can mitochondrial DNA mutations cause sperm dysfunction? by Spiropoulos, John, Turnbull, Douglass M., Chinnery, Patrick F.

“…Very low levels of somatic mitochondrial (mt)DNA deletions have been identified in the semen of infertile men. It has been suggested that these mutations cause…”
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Estimating the temporal relationship between PrPSc detection and incubation period in experimental bovine spongiform encephalopathy of cattle by Arnold, M.E, Ryan, J.B.M, Konold, T, Simmons, M.M, Spencer, Y.I, Wear, A, Chaplin, M, Stack, M, Czub, S, Mueller, R

“…This study examines tissues from sequential-kill, time-course pathogenesis studies to refine estimates of the age at which disease-specific PrP (PrPSc) can…”
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Evidence for Co-infection of Ovine Prion Strains in Classical Scrapie Isolates by Thackray, A.M., Lockey, R., Beck, K.E., Spiropoulos, J., Bujdoso, R.

“…The diversity of strains of ovine prions within classical scrapie isolates was investigated by transmission studies in wild type mice. To determine the maximum…”
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Influence of Breed and Genotype on the Onset and Distribution of Infectivity and Disease-associated Prion Protein in Sheep Following Oral Infection with the Bovine Spongiform Encephalopathy Agent by McGovern, G., Martin, S., Jeffrey, M., Bellworthy, S.J., Spiropoulos, J., Green, R., Lockey, R., Vickery, C.M., Thurston, L., Dexter, G., Hawkins, S.A.C., González, L.

“…The onset and distribution of infectivity and disease-specific prion protein (PrPd) accumulation was studied in Romney and Suffolk sheep of the ARQ/ARQ,…”
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Immunohistochemistry for PrPSc in natural scrapie reveals patterns which are associated with the PrP genotype by Spiropoulos, J., Casalone, C., Caramelli, M., Simmons, M. M.

“…Immunohistochemistry for PrPSc is used widely in scrapie diagnosis. In natural scrapie cases the use of immunohistochemistry (IHC) has revealed the existence…”
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Experimental Classical Bovine Spongiform Encephalopathy: Definition and Progression of Neural PrP Immunolabeling in Relation to Diagnosis and Disease Controls by Simmons, M. M., Spiropoulos, J., Webb, P. R., Spencer, Y. I., Czub, S., Mueller, R., Davis, A., Arnold, M. E., Marsh, S., Hawkins, S. A. C., Cooper, J. A., Konold, T., Wells, G. A. H.

“…Tissues from sequential-kill time course studies of bovine spongiform encephalopathy (BSE) were examined to define PrP immunohistochemical labeling forms and…”
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Unsuccessful oral transmission of scrapie from British sheep to cattle by Konold, T., Spiropoulos, J., Chaplin, M. J., Stack, M. J., Hawkins, S. A. C., Wilesmith, J. W., Wells, G. A. H.

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Transmission of classical scrapie to wild-type mice: the influence of the ovine PrP sequence on lesion profiles by Beck, K. E., Cawthraw, S., Saunders, G. C., Ellis, R., Spiropoulos, J.

“…Susceptibility of sheep to classical scrapie is determined by polymorphisms in the coding region of the prion protein gene ( PRNP ), mainly at codons 136, 154…”
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COMPUTERIZED SEMEN ANALYSIS (CASA): EFFECT OF SEMEN CONCENTRATION AND CHAMBER DEPTH ON MEASUREMENTS by Spiropoulos, J.

“…The purpose of this study was to examine the influence of sample concentration and chamber depth on the performance of a real-time analysis computer-assisted…”
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Experimental bovine spongiform encephalopathy: detection of PrP(Sc) in the small intestine relative to exposure dose and age by Stack, M J, Moore, S J, Vidal-Diez, A, Arnold, M E, Jones, E M, Spencer, Y I, Webb, P, Spiropoulos, J, Powell, L, Bellerby, P, Thurston, L, Cooper, J, Chaplin, M J, Davis, L A, Everitt, S, Focosi-Snyman, R, Hawkins, S A C, Simmons, M M, Wells, G A H

“…European regulations for the control of bovine spongiform encephalopathy (BSE) decree destruction of the intestines from slaughtered cattle, therefore…”
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Experimental Bovine Spongiform Encephalopathy: Detection of PrPSc in the Small Intestine Relative to Exposure Dose and Age by Stack, M.J., Moore, S.J., Vidal-Diez, A., Arnold, M.E., Jones, E.M., Spencer, Y.I., Webb, P., Spiropoulos, J., Powell, L., Bellerby, P., Thurston, L., Cooper, J., Chaplin, M.J., Davis, L.A., Everitt, S., Focosi-Snyman, R., Hawkins, S.A.C., Simmons, M.M., Wells, G.A.H.

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Unsuccessful oral transmission of scrapie from British sheep to cattle by Konold, T., Spiropoulos, J., Chaplin, M. J., Stack, M. J., Hawkins, S. A. C., Wilesmith, J. W., Wells, G. A. H.

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Distribution of Vascular Amyloid in Scrapie-affected Sheep with Different Genotypes by Ligios, C., Dexter, G., Spiropoulos, J., Maestrale, C., Carta, A., Simmons, M.M.

“…Vascular amyloidosis in the brain is a pathological feature of ovine scrapie. Its occurrence varies between sheep, but whether this variation reflects…”
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Have the Biological Properties of Classical BSE Changed After the Implementation of the Reinforced Feed Ban in 1996 in the UK? by Hills, J., Simon, E., Mignacca, S.A., Beck, K., Vickery, C., Lockey, R., Thorne, J., Griffiths, P., Spiropoulos, J.

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Comparative Evaluation in Cattle of Inflammatory Skin Reactions Induced by Tuberculin and Defined Antigen Skin Test Reagents by Sánchez-Cordón, P.J., Floyd, T., Jones, G., Spiropoulos, J., Vordermeier, M., Konold, T., Núñez, A.

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Pulmonary Arteriovenous Malformation in Two Alpacas (Vicugna pacos) in the UK by Bianco, C., Brena, C., Moore, J., Floyd, T., Sanchez-Cordon, P., Reichel, R., Spiropoulos, J., Nunez, A.

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Pathology of Idiopathic Amyloidosis in Four Captive Badgers (Meles meles) by Bianco, C., Sanchez-Cordon, P., Verin, R., Godinho, A., Weyer, U., Lesellier, S., Spiropoulos, J., Floyd, T., Everest, D., Nunez, A.

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