Search Results - "Spirkova, Alexandra"
-
1
Apoptotic cells in mouse blastocysts are eliminated by neighbouring blastomeres
Published in Scientific reports (29-04-2021)“…Apoptosis is a physiological process that occurs commonly during the development of the preimplantation embryo. The present work examines the ability of…”
Get full text
Journal Article -
2
Exposure to neonicotinoid insecticides induces embryotoxicity in mice and rabbits
Published in Toxicology (Amsterdam) (01-12-2017)“…•Neonicotinoid insecticides negatively affect early embryonic development.•Thiacloprid impairs the developmental capacities and quality of both mouse and…”
Get full text
Journal Article -
3
Glutamate can act as a signaling molecule in mouse preimplantation embryos
Published in Biology of reproduction (23-06-2022)“…Free amino acids are present in the natural environment of the preimplantation embryo, and their availability can influence early embryo development. Glutamic…”
Get full text
Journal Article -
4
Fipronil causes toxicity in mouse preimplantation embryos
Published in Toxicology (Amsterdam) (01-12-2018)“…•Fipronil negatively affected in vitro development of mouse preimplantation embryos.•During in vivo testing, fipronil induced apoptosis at the acute reference…”
Get full text
Journal Article -
5
Glucocorticoid receptor isoforms and effects of glucocorticoids in ovulated mouse oocytes and preimplantation embryos
Published in Biology of reproduction (01-02-2019)“…To investigate possible involvement of glucocorticoid receptor (GR) in mediating effects of maternal stress or therapeutically administered glucocorticoids on…”
Get full text
Journal Article -
6
In vitro exposure to pyrethroid-based products disrupts development of mouse preimplantation embryos
Published in Toxicology in vitro (01-06-2019)“…The objective of this study was to evaluate the potential toxicity of pyrethroids (deltamethrin, permethrin, fenvalerate, λ-cyhalothrin), commercial…”
Get full text
Journal Article -
7
Gamma‐aminobutyric acid (GABA) can affect physiological processes in preimplantation embryos via GABAA and GABAB receptors
Published in Reproductive medicine and biology (01-01-2023)“…Purpose Several widely used substances (e.g., some therapeutics or food supplements) can act on gamma‐aminobutyric acid (GABA) receptors, and we investigated…”
Get full text
Journal Article -
8
The Responses of Mouse Preimplantation Embryos to Leptin In Vitro in a Transgenerational Model for Obesity
Published in Frontiers in endocrinology (Lausanne) (13-09-2017)“…The aim of the present study was to test the hypothesis that leptin can directly mediate the negative effect of maternal obesity on preimplantation embryos. As…”
Get full text
Journal Article -
9
Canine Bone Marrow-derived Mesenchymal Stem Cells: Genomics, Proteomics and Functional Analyses of Paracrine Factors[S]
Published in Molecular & cellular proteomics (01-09-2019)“…The study aim was to provide a comprehensive analyse of canine bone marrow derived mesenchymal stem cells (BMMSC) and conditioned media, isolated from healthy…”
Get full text
Journal Article -
10
Canine Bone Marrow-derived Mesenchymal Stem Cells: Genomics, Proteomics and Functional Analyses of Paracrine Factors
Published in Molecular & cellular proteomics (01-09-2019)“…Adult stem cells have become prominent candidates for treating various diseases in veterinary practice. The main goal of our study was therefore to provide a…”
Get full text
Journal Article -
11
Gamma-aminobutyric acid (GABA) can affect physiological processes in preimplantation embryos via GABA A and GABA B receptors
Published in Reproductive medicine and biology (01-01-2023)“…Several widely used substances (e.g., some therapeutics or food supplements) can act on gamma-aminobutyric acid (GABA) receptors, and we investigated whether…”
Get full text
Journal Article -
12
Different response of embryos originating from control and obese mice to insulin in vitro
Published in Journal of Reproduction and Development (2020)“…The aim of the present work was to investigate the impact of maternal obesity on DNA methylation in ovulated oocytes, and to compare the response of in…”
Get full text
Journal Article -
13
Different response of embryos originating from control and obese mice to insulin in vitro
Published in Journal of Reproduction and Development (2021)“…The aim of the present work was to investigate the impact of maternal obesity on DNA methylation in ovulated oocytes, and to compare the response of in…”
Get full text
Journal Article