Search Results - "Spino, M"
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Transport kinetics of iron chelators and their chelates in caco-2 cells
Published in Pharmaceutical research (01-02-2006)“…Caco-2 monolayers were used to contrast the bidirectional transport of iron chelators and their chelates and to estimate fundamental kinetics associated with…”
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2
Sequential cytoprotective responses to Sigma1 ligand-induced endoplasmic reticulum stress
Published in Molecular pharmacology (01-11-2013)“…The Sigma1 receptor (Sigma1) is an endoplasmic reticulum (ER) integral membrane protein that is highly expressed in a number of cancer cell lines. Small…”
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3
STAGED APPROACH TO CORONARY HYBRID CORONARY REVASCULARIZATION IN 515 CONSECUTIVE PATIENTS
Published in Journal of the American College of Cardiology (05-04-2016)“…The treatment strategy incorporates a collaborative heart team approach with interventional cardiologists and a surgeon, who discuss the patient status and…”
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4
Inhibition of tumor cell growth by Sigma1 ligand mediated translational repression
Published in Biochemical and biophysical research communications (21-09-2012)“…► Sigma1 ligand treatment mediates decrease in tumor cell mass. ► Identification of a Sigma1 ligand with reversible translational repressor actions. ►…”
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Chromosomal aberration frequencies in patients with thalassaemia major undergoing therapy with deferiprone and deferoxamine in a comparative crossover study
Published in Mutagenesis (01-09-2003)“…Measurements of chromosomal aberrations were made in 10 thalassaemia major patients treated long‐term with deferiprone (at least 5 years) and compared with an…”
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6
Deferiprone‐induced agranulocytosis: 20 years of clinical observations
Published in American journal of hematology (01-10-2016)“…Use of the iron chelator deferiprone for treatment of iron overload in thalassemia patients is associated with concerns over agranulocytosis, which requires…”
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7
Iron Chelation with Oral Deferiprone in Patients with Thalassemia
Published in The New England journal of medicine (03-12-1998)“…To the Editor: Olivieri et al. (Aug. 13 issue) 1 retrospectively evaluated liver-biopsy specimens from patients with thalassemia who were treated with…”
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8
Commemorating Professor Renzo Galanello (July 21st 1948 - May 13th 2013)
Published in Haematologica (Roma) (01-07-2013)Get full text
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9
Cocaine-induced seizures, arrhythmias and sudden death
Published in Journal of clinical pharmacology (01-07-1988)Get more information
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10
Hypothetical framework for enhanced renal tubular secretion of drugs in cystic fibrosis
Published in Medical hypotheses (01-12-1998)“…Several clinical studies demonstrate reduced serum concentrations of renally excreted drugs in patients with cystic fibrosis (CF). To explain this phenomenon,…”
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11
Bioequivalence of generic aerosol bronchodilators: what are the issues?
Published in Canadian Medical Association journal (CMAJ) (01-11-1989)“…I have attempted to address some critical issues relating to the introduction of generic aerosol bronchodilators in Canada. I approached Genpharm to obtain…”
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12
Dissolution and in vivo evidence of differences in reference products : impact on development of generic drugs
Published in European journal of drug metabolism and pharmacokinetics (01-01-2000)“…The WHO List of International Comparator Pharmaceutical Products (CPP) For Equivalence Assessment of Interchangeable Multi-Source (Generic) Products will…”
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13
The effect of chiropractic care on jet lag of finnish junior elite athletes
Published in Journal of manipulative and physiological therapeutics (01-03-2001)Get full text
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14
Dose-response relationship and reproducibility of the fall in exhaled nitric oxide after inhaled beclomethasone dipropionate therapy in asthma patients
Published in Chest (01-05-2001)“…The fractional concentration of exhaled nitric oxide (FENO) is a marker of asthmatic airway inflammation. We determined the dose response and the…”
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15
Iron chelator research: past, present, and future
Published in Current medicinal chemistry (01-06-2003)“…The occurrence of in vivo iron toxicity in the human body can be categorized into iron overload and non-iron overload conditions. Iron overload conditions are…”
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Comparisons between oral and intraperitoneal 1,25-dihydroxyvitamin D3 therapy in children treated with peritoneal dialysis
Published in Clinical nephrology (01-07-1994)“…Recent studies in adults have suggested that parenteral 1,25-dihydroxyvitamin D3 (1,25[OH]2D3) may have advantages over oral therapy in the management of renal…”
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17
Use of an isolated in situ canine lung perfusion model to evaluate dopamine clearance by the lung
Published in The Journal of pharmacology and experimental therapeutics (01-12-1991)“…An isolated in situ lung perfusion model was used to assess dopamine clearance by the lungs in 12 dogs. The preparation consisted of a closed perfusion system…”
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S144 A MULTICENTRE, RANDOMIZED, NON‐INFERIORITY TRIAL COMPARING THE EFFICACY OF DEFERIPRONE VERSUS DEFERASIROX IN PEDIATRIC PATIENTS AFFECTED BY TRANSFUSION‐DEPENDENT HEMOGLOBINOPATHIES (DEEP‐2 TRIAL)
Published in HemaSphere (01-06-2019)“…Background: While the efficacy and safety of deferiprone (DFP) in adult patients with transfusion‐dependent hemoglobinopathies (TDH) has been extensively…”
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19
Thiol proteases: inhibitors and potential therapeutic targets
Published in Current medicinal chemistry (01-03-2006)“…A better understanding of the biological roles and the pathological consequences of thiol-dependent enzymes has emerged in recent years, and hence considerable…”
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20
High-pressure liquid chromatographic analysis of ceftazidime in serum and urine
Published in Antimicrobial Agents and Chemotherapy (01-11-1983)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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