Search Results - "Spino, M"

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  1. 1

    Transport kinetics of iron chelators and their chelates in caco-2 cells by HUANG, Xi-Ping, SPINO, M, THIESSEN, J. J

    Published in Pharmaceutical research (01-02-2006)
    “…Caco-2 monolayers were used to contrast the bidirectional transport of iron chelators and their chelates and to estimate fundamental kinetics associated with…”
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  2. 2

    Sequential cytoprotective responses to Sigma1 ligand-induced endoplasmic reticulum stress by Schrock, Joel M, Spino, Christina M, Longen, Charles G, Stabler, Stacy M, Marino, Jacqueline C, Pasternak, Gavril W, Kim, Felix J

    Published in Molecular pharmacology (01-11-2013)
    “…The Sigma1 receptor (Sigma1) is an endoplasmic reticulum (ER) integral membrane protein that is highly expressed in a number of cancer cell lines. Small…”
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    STAGED APPROACH TO CORONARY HYBRID CORONARY REVASCULARIZATION IN 515 CONSECUTIVE PATIENTS by Sutter, Francis P, Wertan, MaryAnn, Coady, Paul, Badri, Marwan, Spino, Christina M, McGeehin, Frank, Khan, Amid, Gnall, Eric, Shapiro, Timothy

    “…The treatment strategy incorporates a collaborative heart team approach with interventional cardiologists and a surgeon, who discuss the patient status and…”
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  4. 4

    Inhibition of tumor cell growth by Sigma1 ligand mediated translational repression by Kim, Felix J., Schrock, Joel M., Spino, Christina M., Marino, Jacqueline C., Pasternak, Gavril W.

    “…► Sigma1 ligand treatment mediates decrease in tumor cell mass. ► Identification of a Sigma1 ligand with reversible translational repressor actions. ►…”
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    Chromosomal aberration frequencies in patients with thalassaemia major undergoing therapy with deferiprone and deferoxamine in a comparative crossover study by Marshall, R., Tricta, F., Galanello, R., Leoni, G., Kirkland, D., Minto, S., Spino, M.

    Published in Mutagenesis (01-09-2003)
    “…Measurements of chromosomal aberrations were made in 10 thalassaemia major patients treated long‐term with deferiprone (at least 5 years) and compared with an…”
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  6. 6

    Deferiprone‐induced agranulocytosis: 20 years of clinical observations by Tricta, Fernando, Uetrecht, Jack, Galanello, Renzo, Connelly, John, Rozova, Anna, Spino, Michael, Palmblad, Jan

    Published in American journal of hematology (01-10-2016)
    “…Use of the iron chelator deferiprone for treatment of iron overload in thalassemia patients is associated with concerns over agranulocytosis, which requires…”
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  7. 7

    Iron Chelation with Oral Deferiprone in Patients with Thalassemia by Tricta, F, Spino, M

    Published in The New England journal of medicine (03-12-1998)
    “…To the Editor: Olivieri et al. (Aug. 13 issue) 1 retrospectively evaluated liver-biopsy specimens from patients with thalassemia who were treated with…”
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    Hypothetical framework for enhanced renal tubular secretion of drugs in cystic fibrosis by Woodland, C., Blowey, D., Ito, S., Spino, M., Koren, G.

    Published in Medical hypotheses (01-12-1998)
    “…Several clinical studies demonstrate reduced serum concentrations of renally excreted drugs in patients with cystic fibrosis (CF). To explain this phenomenon,…”
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    Bioequivalence of generic aerosol bronchodilators: what are the issues? by Spino, M

    “…I have attempted to address some critical issues relating to the introduction of generic aerosol bronchodilators in Canada. I approached Genpharm to obtain…”
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  12. 12

    Dissolution and in vivo evidence of differences in reference products : impact on development of generic drugs by SPINO, Michael, YU CHUNG TSANG, POP, Radu

    “…The WHO List of International Comparator Pharmaceutical Products (CPP) For Equivalence Assessment of Interchangeable Multi-Source (Generic) Products will…”
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    Dose-response relationship and reproducibility of the fall in exhaled nitric oxide after inhaled beclomethasone dipropionate therapy in asthma patients by Silkoff, P E, McClean, P, Spino, M, Erlich, L, Slutsky, A S, Zamel, N

    Published in Chest (01-05-2001)
    “…The fractional concentration of exhaled nitric oxide (FENO) is a marker of asthmatic airway inflammation. We determined the dose response and the…”
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  15. 15

    Iron chelator research: past, present, and future by Tam, Tim F, Leung-Toung, Regis, Li, Wanren, Wang, Yingsheng, Karimian, Khashayar, Spino, Michael

    Published in Current medicinal chemistry (01-06-2003)
    “…The occurrence of in vivo iron toxicity in the human body can be categorized into iron overload and non-iron overload conditions. Iron overload conditions are…”
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  16. 16

    Comparisons between oral and intraperitoneal 1,25-dihydroxyvitamin D3 therapy in children treated with peritoneal dialysis by Jones, C L, Vieth, R, Spino, M, Ledermann, S, Kooh, S W, Balfe, J, Balfe, J W

    Published in Clinical nephrology (01-07-1994)
    “…Recent studies in adults have suggested that parenteral 1,25-dihydroxyvitamin D3 (1,25[OH]2D3) may have advantages over oral therapy in the management of renal…”
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  17. 17

    Use of an isolated in situ canine lung perfusion model to evaluate dopamine clearance by the lung by Cardoso, P F, Spino, M, Mayer, E, Shi, S Q, Pop, R D, Puskas, J, Perrier, D, Tong, J, Baines, A D, Patterson, G A

    “…An isolated in situ lung perfusion model was used to assess dopamine clearance by the lungs in 12 dogs. The preparation consisted of a closed perfusion system…”
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    Thiol proteases: inhibitors and potential therapeutic targets by Leung-Toung, Regis, Zhao, Yanqing, Li, Wanren, Tam, Tim F, Karimian, Khashayar, Spino, Michael

    Published in Current medicinal chemistry (01-03-2006)
    “…A better understanding of the biological roles and the pathological consequences of thiol-dependent enzymes has emerged in recent years, and hence considerable…”
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    High-pressure liquid chromatographic analysis of ceftazidime in serum and urine by LEEDER, J. S, SPINO, M, TESORO, A. M, MACLEOD, S

    Published in Antimicrobial Agents and Chemotherapy (01-11-1983)
    “…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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