Search Results - "Spinner, Michael"

Cost Effectiveness of Chimeric Antigen Receptor T-Cell Therapy in Multiply Relapsed or Refractory Adult Large B-Cell Lymphoma by Lin, John K, Muffly, Lori S, Spinner, Michael A, Barnes, James I, Owens, Douglas K, Goldhaber-Fiebert, Jeremy D

“…Two anti-CD19 chimeric antigen receptor T-cell (CAR-T) therapies are approved for diffuse large B-cell lymphoma, axicabtagene ciloleucel (axi-cel) and…”
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GATA2 deficiency: a protean disorder of hematopoiesis, lymphatics, and immunity by Spinner, Michael A., Sanchez, Lauren A., Hsu, Amy P., Shaw, Pamela A., Zerbe, Christa S., Calvo, Katherine R., Arthur, Diane C., Gu, Wenjuan, Gould, Christine M., Brewer, Carmen C., Cowen, Edward W., Freeman, Alexandra F., Olivier, Kenneth N., Uzel, Gulbu, Zelazny, Adrian M., Daub, Janine R., Spalding, Christine D., Claypool, Reginald J., Giri, Neelam K., Alter, Blanche P., Mace, Emily M., Orange, Jordan S., Cuellar-Rodriguez, Jennifer, Hickstein, Dennis D., Holland, Steven M.

“…Haploinsufficiency of the hematopoietic transcription factor GATA2 underlies monocytopenia and mycobacterial infections; dendritic cell, monocyte, B, and…”
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Outcomes and prognostic factors in angioimmunoblastic T-cell lymphoma: final report from the international T-cell Project by Advani, Ranjana H., Skrypets, Tetiana, Civallero, Monica, Spinner, Michael A., Manni, Martina, Kim, Won Seog, Shustov, Andrei R., Horwitz, Steven M., Hitz, Felicitas, Cabrera, Maria Elena, Dlouhy, Ivan, Vassallo, José, Pileri, Stefano A., Inghirami, Giorgio, Montoto, Silvia, Vitolo, Umberto, Radford, John, Vose, Julie M., Federico, Massimo

“…Angioimmunoblastic T-cell lymphoma (AITL) is a unique subtype of peripheral T-cell lymphoma (PTCL) with distinct clinicopathologic features and poor prognosis…”
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Modern principles in the management of nodular lymphocyte‐predominant Hodgkin lymphoma by Spinner, Michael A., Varma, Gaurav, Advani, Ranjana H.

“…Summary Nodular lymphocyte‐predominant Hodgkin lymphoma (NLPHL) is a unique rare subtype of Hodgkin lymphoma (HL) which differs clinically, pathologically and…”
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Current Frontline Treatment of Diffuse Large B-Cell Lymphoma by Spinner, Michael A, Advani, Ranjana H

“…Diffuse large B-cell lymphoma (DLBCL), the most common subtype of non-Hodgkin lymphoma, is an aggressive and biologically heterogeneous disease. Risk…”
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Optimizing Treatment for Relapsed/Refractory Classic Hodgkin Lymphoma in the Era of Immunotherapy by Randall, Michael P, Spinner, Michael A

“…Most patients with classic Hodgkin lymphoma (cHL) are cured with combination chemotherapy, but approximately 10-20% will relapse, and another 5-10% will have…”
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White paper on antimicrobial stewardship in solid organ transplant recipients by So, Miranda, Hand, Jonathan, Forrest, Graeme, Pouch, Stephanie M., Te, Helen, Ardura, Monica I., Bartash, Rachel M., Dadhania, Darshana M., Edelman, Jeffrey, Ince, Dilek, Jorgenson, Margaret R., Kabbani, Sarah, Lease, Erika D., Levine, Deborah, Ohler, Linda, Patel, Gopi, Pisano, Jennifer, Spinner, Michael L., Abbo, Lilian, Verna, Elizabeth C., Husain, Shahid

“…Antimicrobial stewardship programs (ASPs) have made immense strides in optimizing antibiotic, antifungal, and antiviral use in clinical settings. However,…”
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Single-route CNS prophylaxis for aggressive non-Hodgkin lymphomas: real-world outcomes from 21 US academic institutions by Orellana-Noia, Victor Manuel, Reed, Daniel R., McCook, Ashley Alesia, Sen, Jeremy Michael, Barlow, Christian M., Malecek, Mary-Kate, Watkins, Marcus, Kahl, Brad S., Spinner, Michael A., Advani, Ranjana, Voorhees, Timothy J., Snow, Anson, Grover, Natalie Sophia, Ayers, Amy, Romancik, Jason, Liu, Yuxin, Huntington, Scott F., Chavez, Julio C., Saeed, Hayder, Lazaryan, Aleksandr, Raghunathan, Vikram, Spurgeon, Stephen E., Ollila, Thomas A., Del Prete, Christopher, Olszewski, Adam, Ayers, Emily C., Landsburg, Daniel J., Echalier, Benjamin, Lee, Jun, Kamdar, Manali, Caimi, Paolo F., Fu, Timothy, Liu, Jieqi, David, Kevin A., Alharthy, Hanan, Law, Jennie, Karmali, Reem, Shah, Harsh, Stephens, Deborah M., Major, Ajay, Rojek, Alexandra E., Smith, Sonali M., Yellala, Amulya, Kallam, Avyakta, Nakhoda, Shazi, Khan, Nadia, Sohail, Mohammad Ahsan, Hill, Brian T., Barrett-Campbell, Odeth, Lansigan, Frederick, Switchenko, Jeffrey, Cohen, Jonathon, Portell, Craig A.

“…Prophylaxis is commonly used to prevent central nervous sy stem (CNS) relapse in diffuse large B-cell lymphoma (DLBCL), with no clear standard of care. We…”
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A Conserved Role for Vezatin Proteins in Cargo-Specific Regulation of Retrograde Axonal Transport by Spinner, Michael A, Pinter, Katherine, Drerup, Catherine M, Herman, Tory G

“…Abstract Vertebrate Vezatin is associated with the regulation of cell-cell junctions. A distantly-related¬Aspergillus¬protein, VezA, promotes dynein-dependent…”
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Pharmacology of testosterone replacement therapy preparations by Shoskes, Jennifer J, Wilson, Meghan K, Spinner, Michael L

“…The goal of testosterone replacement therapy (TRT) is to return serum testosterone levels to within physiologic range and improve symptoms in hypogonadal men…”
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The Genome-Wide Binding Profile for Human RE1 Silencing Transcription Factor Unveils a Unique Genetic Circuitry in Hippocampus by McGann, James C, Spinner, Michael A, Garg, Saurabh K, Mullendorff, Karin A, Woltjer, Randall L, Mandel, Gail

“…Early studies in mouse neurodevelopment led to the discovery of the RE1 Silencing Transcription Factor (REST) and its role as a master repressor of neuronal…”
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GATA2 deficiency underlying severe blastomycosis and fatal herpes simplex virus–associated hemophagocytic lymphohistiocytosis by Spinner, Michael A., MD, Ker, Jennifer P., MD, Stoudenmire, Charles J., MD, Fadare, Oluwole, MD, Mace, Emily M., PhD, Orange, Jordan S., MD, PhD, Hsu, Amy P., BA, Holland, Steven M., MD

“…GATA2 mutations underlie at least 5 previously described disorders: monocytopenia and mycobacterial infections (MonoMAC) syndrome; dendritic cell, monocyte, B…”
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Risk-adapted therapy for advanced-stage Hodgkin lymphoma by Spinner, Michael A, Advani, Ranjana H

“…More than 80% of patients with advanced-stage Hodgkin lymphoma are now cured with contemporary treatment approaches. The ongoing challenge is how to further…”
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Pulmonary Manifestations of GATA2 Deficiency by Marciano, Beatriz E., Olivier, Kenneth N., Folio, Les R., Zerbe, Christa S., Hsu, Amy P., Freeman, Alexandra F., Filie, Armando C., Spinner, Michael A., Sanchez, Lauren A., Lovell, Jana P., Parta, Mark, Cuellar-Rodriguez, Jennifer M., Hickstein, Dennis D., Holland, Steven M.

“…GATA2 deficiency is a genetic disorder of hematopoiesis, lymphatics, and immunity caused by autosomal dominant or sporadic mutations in GATA2. The disease has…”
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Checkpoint Blockade Treatment May Sensitize Hodgkin Lymphoma to Subsequent Therapy by Carreau, Nicole A., Pail, Orrin, Armand, Philippe, Merryman, Reid, Advani, Ranjana H., Spinner, Michael A., Herrera, Alex, Chen, Robert, Tomassetti, Sarah, Ramchandren, Radhakrishnan, Hamid, Muhammad S., Assouline, Sarit, Santiago, Raoul, Wagner‐Johnston, Nina, Paul, Suman, Svoboda, Jakub, Bair, Steven, Barta, Stefan, Liu, Yang, Nathan, Sunita, Karmali, Reem, Burkart, Madelyn, Torka, Pallawi, David, Kevin, Wei, Catherine, Lansigan, Frederick, Emery, Lukas, Persky, Daniel, Smith, Sonali, Godfrey, James, Chavez, Julio, Xia, Yuhe, Troxel, Andrea B., Diefenbach, Catherine

“…Background Targeted therapies and checkpoint blockade therapy (CBT) have shown efficacy for patients with Hodgkin lymphoma (HL) in the relapsed and refractory…”
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Drosophila Syd-1 Has RhoGAP Activity That Is Required for Presynaptic Clustering of Bruchpilot/ELKS but Not Neurexin-1 by Spinner, Michael A, Walla, David A, Herman, Tory G

“…Syd-1 proteins are required for presynaptic development in worm, fly, and mouse. Syd-1 proteins in all three species contain a Rho GTPase activating protein…”
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Improved outcomes for relapsed/refractory Hodgkin lymphoma after autologous transplantation in the era of novel agents by Spinner, Michael A., Sica, R. A., Tamaresis, John S., Lu, Ying, Chang, Cheryl, Lowsky, Robert, Frank, Matthew J., Johnston, Laura J., Miklos, David B., Muffly, Lori S., Negrin, Robert S., Rezvani, Andrew R., Shiraz, Parveen, Shizuru, Judith A., Weng, Wen-Kai, Binkley, Michael S., Hoppe, Richard T., Advani, Ranjana H., Arai, Sally

“…•OS for relapsed/refractory Hodgkin lymphoma after autologous HCT has improved after the approval of BV and the PD-1 inhibitors.•PD-1 inhibitor-based salvage…”
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Increased double-negative αβ+ T-cells reveal adult-onset autoimmune lymphoproliferative syndrome in a patient with IgG4-related disease by Brar, Nivaz, Spinner, Michael A, Baker, Matthew C, Advani, Ranjana H, Natkunam, Yasodha, Lewis, David B, Silva, Oscar

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Long-term Survivors and Failures of CAR-T Therapy for Lymphoma: Is there a Role for Allogeneic Transplantation After the CAR-T Crash? by Spinner, Michael A., Komanduri, Krishna V.

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Amyloid-β Dynamics Correlate with Neurological Status in the Injured Human Brain by Brody, David L, Magnoni, Sandra, Schwetye, Kate E, Spinner, Michael L, Esparza, Thomas J, Stocchetti, Nino, Zipfel, Gregory J, Holtzman, David M

“…The amyloid-β peptide (Aβ) plays a central pathophysiological role in Alzheimer's disease, but little is known about the concentration and dynamics of this…”
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