Search Results - "Spink, C"

Legacy and Emerging Per- and Polyfluoroalkyl Substances: Analytical Techniques, Environmental Fate, and Health Effects by Brase, Richard A, Mullin, Elizabeth J, Spink, David C

“…Due to their unique chemical properties, per- and polyfluoroalkyl substances (PFAS) have been used extensively as industrial surfactants and processing aids…”
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Elevated levels of per- and polyfluoroalkyl substances (PFAS) in freshwater benthic macroinvertebrates from the Hudson River Watershed by Brase, Richard A., Schwab, Holly E., Li, Lingyun, Spink, David C.

“…Per- and polyfluoroalkyl substances (PFAS) are contaminants of global concern due to their persistence and associated negative health effects. Considerable…”
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Androgenic steroids in Over-the-Counter dietary Supplements: Analysis for association with adverse health effects by Tran, Buu N., Okoniewski, Richard, Spink, Barbara C., LeMaster, David M., Aldous, Kenneth M., Spink, David C.

“…•Residents of a New York Community became ill with maladies of unknown cause.•All of the patients were found to have used nutritional supplements from the same…”
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Structure and activity of particulate methane monooxygenase arrays in methanotrophs by Zhu, Yanan, Koo, Christopher W., Cassidy, C. Keith, Spink, Matthew C., Ni, Tao, Zanetti-Domingues, Laura C., Bateman, Benji, Martin-Fernandez, Marisa L., Shen, Juan, Sheng, Yuewen, Song, Yun, Yang, Zhengyi, Rosenzweig, Amy C., Zhang, Peijun

“…Methane-oxidizing bacteria play a central role in greenhouse gas mitigation and have potential applications in biomanufacturing. Their primary metabolic…”
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Genetic and epigenetic regulation of AHR gene expression in MCF-7 breast cancer cells: Role of the proximal promoter GC-rich region by Englert, Neal A., Turesky, Robert J., Han, Weiguo, Bessette, Erin E., Spivack, Simon D., Caggana, Michele, Spink, David C., Spink, Barbara C.

“…The aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor, contributes to carcinogenesis through its role in the regulation of cytochrome…”
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Noninvasive determination of human cortisol and dehydroepiandrosterone sulfate using liquid chromatography-tandem mass spectrometry by Cao, Zhimin (Tim), Wemm, Stephanie E., Han, Liqiao, Spink, David C., Wulfert, Edelgard

“…Liquid chromatography-tandem mass spectrometry (LC-MS/MS) for measurements of steroids in human saliva has garnered increased interest in the area of clinical…”
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Liquid chromatography-tandem mass spectrometry analysis of 17-hydroxyprogesterone in dried blood spots revealed matrix effect on immunoassay by Han, Liqiao, Tavakoli, Norma P., Morrissey, Mark, Spink, David C., Cao, Zhimin (Tim)

“…Immunoassays for measuring 17-hydroxyprogesterone (17-OHP) produce high rates of false positives that impact the identification of congenital adrenal…”
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Analysis of the AHR gene proximal promoter GGGGC-repeat polymorphism in lung, breast, and colon cancer by Spink, Barbara C., Bloom, Michael S., Wu, Susan, Sell, Stewart, Schneider, Erasmus, Ding, Xinxin, Spink, David C.

“…The aryl hydrocarbon receptor (AhR) regulates expression of numerous genes, including those of the CYP1 gene family. With the goal of determining factors that…”
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Understanding the Human Health Effects of Chemical Mixtures by Carpenter, David O., Arcaro, Kathleen, Spink, David C.

“…Most research on the effects of chemicals on biologic systems is conducted on one chemical at a time. However, in the real world people are exposed to…”
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Comparison of meniscal T1rho- and T2-relaxation times in professional female volleyball players and healthy controls using 3T MRI: A pilot study by Spink, C., Henes, F.O., Da Cruz, L., Sinn, M., Behzadi, C., Schoen, G., Welsch, G.H., Adam, G., Bannas, P., Maas, K.J.

“…Comparison of meniscal T1rho- and T2*-relaxation times in professional female volleyball players and healthy controls to determine if relaxation times are…”
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Differential expression of CYP1A1 and CYP1B1 in human breast epithelial cells and breast tumor cells by SPINK, D. C, SPINK, B. C, CAO, J. Q, DEPASQUALE, J. A, PENTECOST, B. T, FASCO, M. J, YING LI, SUTTER, T. R

“…Human cytochromes P450 1A1 (CYP1A1) and P450 1B1 (CYP1B1) catalyze the metabolic activation of a number of procarcinogens and the hydroxylation of…”
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Subthreshold diode micropulse panretinal photocoagulation for proliferative diabetic retinopathy by Luttrull, J K, Musch, D C, Spink, C A

“…Purpose To report the visual acuity and clinical outcomes of a pilot study of subthreshold diode micropulse (SDM) panretinal photocoagulation (PRP) for…”
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Induction of CYP1A1 and CYP1B1 by benzo( k)fluoranthene and benzo( a)pyrene in T-47D human breast cancer cells: Roles of PAH interactions and PAH metabolites by Spink, David C., Wu, Susan J., Spink, Barbara C., Hussain, Mirza M., Vakharia, Dilip D., Pentecost, Brian T., Kaminsky, Laurence S.

“…The interactions of polycyclic aromatic hydrocarbons (PAH) and cytochromes P450 (CYP) are complex; PAHs are enzyme inducers, substrates, and inhibitors. In…”
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17 beta-estradiol hydroxylation catalyzed by human cytochrome P450 1B1 by Hayes, C L, Spink, D C, Spink, B C, Cao, J Q, Walker, N J, Sutter, T R

“…The 4-hydroxy metabolite of 17 beta-estradiol (E2) has been implicated in the carcinogenicity of this hormone. Previous studies showed that aryl…”
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Transient induction of cytochromes P450 1A1 and 1B1 in MCF-7 human breast cancer cells by indirubin by Spink, Barbara C., Hussain, Mirza M., Katz, Barbara H., Eisele, Leslie, Spink, David C.

“…The aryl hydrocarbon receptor (AhR), when activated by exogenous ligands such as 2,3,7,8-tetrachlorodibenzo- p-dioxin (TCDD), regulates expression of several…”
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Investigation of Vaping Fluids Recovered From New York State E-Cigarette or Vaping Product Use-Associated Lung Injury Patients by Lu, Shijun (Jimmy), Li, Lingyun, Duffy, Bryan C., Dittmar, Mark A., Durocher, Lorie A., Panawennage, Deepika, Delaney-Baldwin, Em R., Spink, David C.

“…E-cigarette or vaping product use-associated lung injury (EVALI) is a serious pulmonary condition that is associated with the extended use of certain vaping…”
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Expression of the aryl hydrocarbon receptor is not required for the proliferation, migration, invasion, or estrogen-dependent tumorigenesis of MCF-7 breast cancer cells by Spink, Barbara C., Bennett, James A., Lostritto, Nicole, Cole, Jacquelyn R., Spink, David C.

“…The AhR was initially identified as a ligand‐activated transcription factor mediating effects of chlorinated dioxins and polycyclic aromatic hydrocarbons on…”
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Noise reduction angiographic imaging technology reduces radiation dose during bronchial artery embolization by Spink, C., Avanesov, M., Schmidt, T., Grass, M., Schoen, G., Adam, G., Koops, A., Ittrich, H., Bannas, P.

“…•Noise reduction imaging technology reduced radiation exposure up to 59%.•No significant loss in image quality was observed.•Procedure duration and contrast…”
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Radiation dose reduction during transjugular intrahepatic portosystemic shunt implantation using a new imaging technology by Spink, C, Avanesov, M, Schmidt, T, Grass, M, Schoen, G, Adam, G, Bannas, P, Koops, A

“…Highlights • The new imaging technology halved the radiation exposure. • DSA image quality observed was not decreased after technology upgrade. • Radiation…”
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Persistent and non-persistent changes in gene expression result from long-term estrogen exposure of MCF-7 breast cancer cells by Englert, Neal A., Spink, Barbara C., Spink, David C.

“…▶ Long-term estrogen exposure in MCF-7 cells causes a persistent up-regulation of the AhR. ▶ Numerous genes up-regulated by long-term estrogen are insensitive…”
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