Search Results - "Spineli, Loukia M"

An empirical comparison of Bayesian modelling strategies for missing binary outcome data in network meta-analysis by Spineli, Loukia M

“…A number of strategies have been proposed to handle missing binary outcome data (MOD) in systematic reviews. However, none of these have been evaluated…”
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Local inconsistency detection using the Kullback-Leibler divergence measure by Spineli, Loukia M

“…The standard approach to local inconsistency assessment typically relies on testing the conflict between the direct and indirect evidence in selected treatment…”
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Medium‐ and long‐term clinical benefits of periodontal regenerative/reconstructive procedures in intrabony defects: Systematic review and network meta‐analysis of randomized controlled clinical studies by Stavropoulos, Andreas, Bertl, Kristina, Spineli, Loukia M., Sculean, Anton, Cortellini, Pierpaolo, Tonetti, Maurizio

“…Background Systematic reviews have established the short‐term improvements of periodontal regenerative/reconstructive procedures compared to conventional…”
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Comparative efficacy and acceptability of antimanic drugs in acute mania: a multiple-treatments meta-analysis by Cipriani, Andrea, Dr, Barbui, Corrado, Prof, Salanti, Georgia, Prof, Rendell, Jennifer, PhD, Brown, Rachel, BPharm, Stockton, Sarah, BA(Hons), Purgato, Marianna, PsyD, Spineli, Loukia M, MSc, Goodwin, Guy M, Prof, Geddes, John R, Prof

“…Summary Background Conventional meta-analyses have shown inconsistent results for efficacy of pharmacological treatments for acute mania. We did a…”
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Language bias in orthodontic systematic reviews: A meta-epidemiological study by Mheissen, Samer, Spineli, Loukia M, Daraqel, Baraa, Alsafadi, Ahmad Saleem

“…Orthodontic systematic reviews (SRs) include studies published mostly in English than non-English languages. Including only English studies in SRs may result…”
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How robust are findings of pairwise and network meta-analysis in the presence of missing participant outcome data? by Spineli, Loukia M, Kalyvas, Chrysostomos, Papadimitropoulou, Katerina

“…To investigate the prevalence of robust conclusions in systematic reviews addressing missing (participant) outcome data via a novel framework of sensitivity…”
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Comparison of exclusion, imputation and modelling of missing binary outcome data in frequentist network meta-analysis by Spineli, Loukia M, Kalyvas, Chrysostomos

“…Missing participant outcome data (MOD) are ubiquitous in systematic reviews with network meta-analysis (NMA) as they invade from the inclusion of clinical…”
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Pattern-mixture model in network meta-analysis of binary missing outcome data: one-stage or two-stage approach? by Spineli, Loukia M, Papadimitropoulou, Katerina, Kalyvas, Chrysostomos

“…Trials with binary outcomes can be synthesised using within-trial exact likelihood or approximate normal likelihood in one-stage or two-stage approaches,…”
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Low awareness of the transitivity assumption in complex networks of interventions: a systematic survey from 721 network meta-analyses by Spineli, Loukia M, Kalyvas, Chrysostomos, Yepes-Nuñez, Juan Jose, García-Sierra, Andrés Mauricio, Rivera-Pinzón, Diana C, Seide, Svenja E, Papadimitropoulou, Katerina

“…The transitivity assumption is the cornerstone of network meta-analysis (NMA). Violating transitivity compromises the credibility of the indirect estimates…”
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Root coverage stability: A systematic overview of controlled clinical trials with at least 5 years of follow‐up by Bertl, Kristina, Spineli, Loukia M., Mohandis, Khalid, Stavropoulos, Andreas

“…Objectives To systematically assess the long‐term outcome (≥5 years) of root coverage procedures reported in controlled clinical trials. Material and Methods…”
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Critical appraisal of arguments for the delayed-start design proposed as alternative to the parallel-group randomized clinical trial design in the field of rare disease by Spineli, Loukia M, Jenz, Eva, Großhennig, Anika, Koch, Armin

“…A number of papers have proposed or evaluated the delayed-start design as an alternative to the standard two-arm parallel group randomized clinical trial (RCT)…”
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A systematic survey shows that reporting and handling of missing outcome data in networks of interventions is poor by Spineli, Loukia M, Yepes-Nuñez, Juan J, Schünemann, Holger J

“…To provide empirical evidence about prevalence, reporting and handling of missing outcome data in systematic reviews with network meta-analysis and…”
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Prediction interval in random-effects meta-analysis by Spineli, Loukia M., Pandis, Nikolaos

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Quantitative microstructural cerebral changes in neurofibromatosis type 1 by Bültmann, Eva, Spineli, Loukia M., Hartmann, Hans, Sander, Annette, Lanfermann, Heinrich

“…To evaluate microstructural cerebral changes in children with neurofibromatosis type 1 (NF1) based on T2 relaxation time measurements at 3Tesla. From our…”
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Signatures of T and B Cell Development, Functional Responses and PD-1 Upregulation After HCMV Latent Infections and Reactivations in Nod.Rag.Gamma Mice Humanized With Cord Blood CD34 + Cells by Theobald, Sebastian J, Khailaie, Sahamoddin, Meyer-Hermann, Michael, Volk, Valery, Olbrich, Henning, Danisch, Simon, Gerasch, Laura, Schneider, Andreas, Sinzger, Christian, Schaudien, Dirk, Lienenklaus, Stefan, Riese, Peggy, Guzman, Carlos A, Figueiredo, Constanca, von Kaisenberg, Constantin, Spineli, Loukia M, Glaesener, Stephanie, Meyer-Bahlburg, Almut, Ganser, Arnold, Schmitt, Michael, Mach, Michael, Messerle, Martin, Stripecke, Renata

“…Human cytomegalovirus (HCMV) latency is typically harmless but reactivation can be largely detrimental to immune compromised hosts. We modeled latency and…”
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A Revised Framework to Evaluate the Consistency Assumption Globally in a Network of Interventions by Spineli, Loukia M.

“…Background The unrelated mean effects (UME) model has been proposed for evaluating the consistency assumption globally in the network of interventions…”
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Multidimensional Analysis Integrating Human T-Cell Signatures in Lymphatic Tissues with Sex of Humanized Mice for Prediction of Responses after Dendritic Cell Immunization by Volk, Valery, Reppas, Andreas I, Robert, Philippe A, Spineli, Loukia M, Sundarasetty, Bala Sai, Theobald, Sebastian J, Schneider, Andreas, Gerasch, Laura, Deves Roth, Candida, Klöss, Stephan, Koehl, Ulrike, von Kaisenberg, Constantin, Figueiredo, Constanca, Hatzikirou, Haralampos, Meyer-Hermann, Michael, Stripecke, Renata

“…Mice transplanted with human cord blood-derived hematopoietic stem cells (HSCs) became a powerful experimental tool for studying the heterogeneity of human…”
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Modeling missing binary outcome data while preserving transitivity assumption yielded more credible network meta-analysis results by Spineli, Loukia M.

“…The objectives of this study were to elaborate on the conceptual evaluation of transitivity assumption in the context of binary missing participant outcome…”
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Evaluating the impact of imputations for missing participant outcome data in a network meta-analysis by Spineli, Loukia M, Higgins, Julian PT, Cipriani, Andrea, Leucht, Stefan, Salanti, Georgia

“…Background In a meta-analysis of trials with missing outcome data, a parameter known as informative missing odds ratio (IMOR) can be used to quantify the…”
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Problems and pitfalls in subgroup analysis and meta-regression by Spineli, Loukia M., Pandis, Nikolaos

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