Search Results - "Spilman, C. H."

Discovery, isolation, structure elucidation, and biosynthesis of U-106305, a cholesteryl ester transfer protein inhibitor from UC 11136 by Kuo, M. S, Zielinski, R. J, Cialdella, J. I, Marschke, C. K, Dupuis, M. J, Li, G. P, Kloosterman, D. A, Spilman, C. H, Marshall, V. P

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Unusual steroid specificity of the cell surface progesterone receptor on human sperm by Blackmore, P F, Fisher, J F, Spilman, C H, Bleasdale, J E

“…The steroid specificity of the cell surface progesterone receptor in human sperm was examined with the use of progesterone, testosterone, and androstane…”
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Pioglitazone hydrochloride inhibits cholesterol absorption and lowers plasma cholesterol concentrations in cholesterol-fed rats by Colca, J. R., Dailey, C. F., Palazuk, B. J., Hillman, R. M., Dinh, D. M., Melchior, G. W., Spilman, C. H.

“…Pioglitazone hydrochloride inhibits cholesterol absorption and lowers plasma cholesterol concentrations in cholesterol-fed rats. J R Colca , C F Dailey , B J…”
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Novenamines as inhibitors of two independent enzymes during DNA replication in a toluenized Escherichia coli cell system by Althaus, Irene W., Kézdy, Ferenc J., Peterson, Tillie, Spilman, Charles H., Reusser, Fritz

“…The amphiphilic novenamines described in this report have been shown previously to be specific inhibitors of human immunodeficiency virus type 1 reverse…”
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Inhibition of platelet thromboxane A2 synthase activity by sodium 5-(3'-pyridinylmethyl)benzofuran-2-carboxylate by Gorman, R R, Johnson, R A, Spilman, C H, Aiken, J W

“…This report outlines the activity of a new thromboxane synthase inhibitor sodium, 5-(3-pyridinylmethyl)-2-benzofurancarboxylate, (U-63557A). U-63557A is a…”
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Synthesis and hypocholesterolemic activity of 6,7-dihydro-4H-pyrazolo[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-diones, novel inhibitors of acylCoA: cholesterol O-acyltransferase by Larsen, Scott D, Spilman, Charles H, Bell, Frank P, Dinh, Dac M, Martinborough, Esther, Wilson, Gracella J

“…A novel series of 6,7-dihydro-4H-pyrazolo[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-dione inhibitors of the enzyme acyl-CoA:cholesterol O-acyltransferase is…”
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Cholesterol-lowering bile acid-binding agents: novel lipophilic polyamines by Thomas, Edward W, Cudahy, Michele M, Spilman, Charles H, Dinh, Dac M, Watkins, Tommie L, Vidmar, Thomas J

“…A series of novel lipophilic polyamines was synthesized by the sodium cyanoborohydride-mediated reductive amination of various ketones and aldehydes with the…”
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Strategies in the design of solution-stable, water-soluble prodrugs III: influence of the pro-moiety on the bioconversion of 21-esters of corticosteroids by Anderson, B D, Conradi, R A, Spilman, C H, Forbes, A D

“…Succinate esters and many other carboxylic acid esters utilized as water-soluble prodrugs have limited utility due to their aqueous solution instability. In an…”
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Receptor binding activity of lipid recombinants of apolipoprotein B-100 thrombolytic fragments by Corsini, A, Spilman, C H, Innerarity, T L, Arnold, K S, Rall, Jr, S C, Boyles, J K, Mahley, R W

“…Apolipoprotein (apo) B-100, the protein constituent of low density lipoproteins (LDL), is the determinant responsible for LDL binding to the apoB,E(LDL)…”
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Synthesis and biological activity of prostaglandin lactones by Bundy, Gordon L., Peterson, D. C., Cornette, J. C., Miller, W. L., Spilman, C. H., Wilks, J. W.

“…Most of the primary prostaglandins and several biologically important prostaglandin analogues were converted to 1,9-, 1,11- or 1,15-lactones, in order to…”
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Oviductal Motility Amplitude and Ovarian Steroid Secretion During Egg Transport in the Rabbit by Spilman, C H, Shaikh, A A, Harper, M J

“…New Zealand White rabbits were used to measure oviductal mortility amplitude in vivo and ovarian vein concentrations of estrone (E 1 ), estradiol (E 2 ),…”
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Effect of Prostaglandins on Oviduct Motility in Estrous Rabbits by Spilman, C H, Harper, M J

“…Ballon-tipped fluid-filled catheters were used to study the effects of prostaglandin (PG) E 1 , E 2 , F 1α , and F 2α on the muscular activity of the…”
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Effect of prostaglandins on the development of rabbit embryos by Spilman, C H

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Relationship between progesterone receptor binding and progestin biological activity by Spilman, C H, Wilks, J W, Campbell, J A

“…The binding affinities of a series of steroidal compounds for the hamster uterine progesterone receptor were determined using two sets of incubation…”
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Arrest of folliculogenesis and inhibition of ovulation in the monkey following weekly administration of progestins by Wilks, J W, Spilman, C H, Campbell, J A

“…Studies were undertaken in the rhesus monkey to determine whether development of a dominant ovarian follicle could be repeatedly arrested by the administration…”
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Effect of Ovariectomy on Egg Transport in the Rabbit by Spilman, C H, Beauving, D C

“…The importance of pre- and postovulatory ovarian steroid secretion on egg transport through the entire oviduct was studied in the rabbit. Estrous New Zealand…”
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Comparison of the Effects of Adrenergic Drugs and Prostaglandins on Rabbit Oviduct Motility by Spilman, C H, Harper, M J

“…The effects of adrenergic drugs and prostaglandins (PGs) on rabbit oviductal isthmus motility were compared. Balloon-tipped fluid-filled catheters placed in…”
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Fluid retention by the rabbit oviduct by Spilman, C H

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Oviduct motility in the rhesus monkey: spontaneous activity and response to prostaglandins by Spilman, C H

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Effects of prostaglandins on oviductal motility and egg transport by Spilman, C H, Harper, M J

“…The effects of prostaglandins (PGs) on muscular activity of the oviductal isthmus and on the rate of tubal egg transport are reviewed. In consideration of the…”
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