Search Results - "Spiesshoefer, Jens"
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Mortality in pulmonary arterial hypertension: prediction by the 2015 European pulmonary hypertension guidelines risk stratification model
Published in The European respiratory journal (01-08-2017)“…The 2015 European pulmonary hypertension (PH) guidelines propose a risk stratification strategy for patients with pulmonary arterial hypertension (PAH). Low-,…”
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Evaluation of Respiratory Muscle Strength and Diaphragm Ultrasound: Normative Values, Theoretical Considerations, and Practical Recommendations
Published in Respiration (01-05-2020)“…Reference values derived from existing diaphragm ultrasound protocols are inconsistent, and the association between sonographic measures of diaphragm function…”
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Sleep - the yet underappreciated player in cardiovascular diseases: A clinical review from the German Cardiac Society Working Group on Sleep Disordered Breathing
Published in European journal of preventive cardiology (10-04-2021)“…Patients with a wide variety of cardiovascular diseases, including arterial and pulmonary hypertension, arrhythmia, coronary artery disease and heart failure,…”
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Diaphragm dysfunction as a potential determinant of dyspnea on exertion in patients 1 year after COVID-19-related ARDS
Published in Respiratory research (15-07-2022)“…Abstract Some COVID-19 patients experience dyspnea without objective impairment of pulmonary or cardiac function. This study determined diaphragm function and…”
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Effective non-invasive ventilation reduces muscle sympathetic nerve activity in patients with stable hypercapnic COPD
Published in Clinical autonomic research (01-04-2024)“…Increased sympathetic drive is of prognostic significance in chronic obstructive pulmonary disease (COPD) but its determinants remain poorly understood. One…”
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Sympathetic and Vagal Nerve Activity in COPD: Pathophysiology, Presumed Determinants and Underappreciated Therapeutic Potential
Published in Frontiers in physiology (23-06-2022)“…This article explains the comprehensive state of the art assessment of sympathetic (SNA) and vagal nerve activity recordings in humans and highlights the…”
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Cardiopulmonary work up of patients with and without fatigue 6 months after COVID-19
Published in Scientific reports (27-10-2022)“…The pathogenesis of long-Covid symptoms remains incompletely understood. Therefore, we aimed to determine cardiopulmonary limitations 6 months after surviving…”
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APAP therapy does not improve impaired sleep quality and sympatho-vagal balance: a randomized trial in patients with obstructive sleep apnea and systolic heart failure
Published in Sleep & breathing (01-03-2020)“…Purpose In heart failure with reduced ejection fraction (HFrEF), the effects of automatic positive airway pressure therapy (APAP) for obstructive sleep apnea…”
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Response to: Respiratory muscle dysfunction in facioscapulohumeral muscular dystrophy. Letter to the editor—reference article: sleep-related breathing disorders in facioscapulohumeral dystrophy (https://doi.org/10.1007/s11325-019-01843-1) by Santos DB et al
Published in Sleep & breathing (01-06-2020)Get full text
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Diaphragm Involvement in Heart Failure: Mere Consequence of Hypoperfusion or Mediated by HF-Related Pro-inflammatory Cytokine Storms?
Published in Frontiers in physiology (24-10-2019)Get full text
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Effects of nasal high flow on nocturnal hypercapnia, sleep, and sympathovagal balance in patients with neuromuscular disorders
Published in Sleep & breathing (01-09-2021)“…Purpose In neuromuscular disorders (NMD), inspiratory muscle weakness may cause sleep-related hypoventilation requiring non-invasive ventilation (NIV)…”
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Validity of transit time–based blood pressure measurements in patients with and without heart failure or pulmonary arterial hypertension across different breathing maneuvers
Published in Sleep & breathing (01-03-2020)“…Purpose Pulse transit time (PTT) derived by ECG and plethysmographic signal can be a promising alternative to invasive or oscillometry-based blood pressure…”
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Effects of hyperventilation length on muscle sympathetic nerve activity in healthy humans simulating periodic breathing
Published in Frontiers in physiology (05-09-2022)“…Background: Periodic breathing (PB) is a cyclical breathing pattern composed of alternating periods of hyperventilation (hyperpnea, HP) and central apnea (CA)…”
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Central Apneas Are More Detrimental in Female Than in Male Patients With Heart Failure
Published in Journal of the American Heart Association (01-03-2022)“…Background Central apneas (CA) are a frequent comorbidity in patients with heart failure (HF) and are associated with worse prognosis. The clinical and…”
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Correction to: Validity of transit time–based blood pressure measurements in patients with and without heart failure or pulmonary arterial hypertension across different breathing maneuvers
Published in Sleep & breathing (01-09-2020)“…After the publication of the original manuscript we found that the calculation of the supplemental data regarding the capacity of PTT-based blood pressure (BP)…”
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Respiratory Muscle Function Tests and Diaphragm Ultrasound Predict Nocturnal Hypoventilation in Slowly Progressive Myopathies
Published in Frontiers in neurology (14-10-2021)“…Introduction: In slowly progressive myopathies, diaphragm weakness early manifests through sleep-related hypoventilation as reflected by nocturnal hypercapnia…”
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Effects of central apneas on sympathovagal balance and hemodynamics at night: impact of underlying systolic heart failure
Published in Sleep & breathing (01-06-2021)“…Background Increased sympathetic drive is the key determinant of systolic heart failure progression, being associated with worse functional status,…”
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Effects of nasal high flow on sympathovagal balance, sleep, and sleep-related breathing in patients with precapillary pulmonary hypertension
Published in Sleep & breathing (01-06-2021)“…Background In precapillary pulmonary hypertension (PH), nasal high flow therapy (NHF) may favorably alter sympathovagal balance (SVB) and sleep-related…”
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Successful treatment of prolonged COVID-19 with Bamlanivimab in a patient with severe B-Cell aplasia due to treatment with an anti-CD20 monoclonal antibody: A case report
Published in Respiratory medicine case reports (01-01-2021)“…A 71-year-old female patient with B-cell depletion due to treatment with an anti-CD20 monoclonal antibody was admitted for worsening COVID-19. Overall, she had…”
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Heterogenous haemodynamic effects of adaptive servoventilation therapy in sleeping patients with heart failure and Cheyne–Stokes respiration compared to healthy volunteers
Published in Heart and vessels (01-07-2016)“…This study investigated the haemodynamic effects of adaptive servoventilation (ASV) in heart failure (HF) patients with Cheyne–Stokes respiration (CSR) versus…”
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