Search Results - "Spiess, Arthur J."

Novel Trypanocidal Analogs of 5′-(Methylthio)-Adenosine by SUFRIN, Janice R, SPIESS, Arthur J, MARASCO, Canio J, RATTENDI, Donna, BACCHI, Cyrus J

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Improved synthesis of beta-D-6-methylpurine riboside and antitumor effects of the beta-D- and alpha-D-anomers by Marasco, Jr, Canio J, Pera, Paula J, Spiess, Arthur J, Bernacki, Ralph, Sufrin, Janice R

“…6-Methylpurine-beta-D-riboside (beta-D-MPR) has been synthesized by coupling 6-methylpurine and 1-O-acetyl-2,3,5-tri-O-benzoyl-D-ribose using conditions that…”
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Synthesis and antiproliferative effects of novel 5'-fluorinated analogs of 5'-deoxy-5'-(methylthio)adenosine by Sufrin, Janice R, Spiess, Arthur J, Kramer, Debora L, Libby, Paul R, Porter, Carl W

“…5'-Deoxy-5'-[(monofluoromethyl)thio]adenosine (9) and 5'-deoxy-5'-fluoro-5'-(methylthio)adenosine (10), two novel analogues of…”
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Metabolic effects of a methylthioadenosine phosphorylase substrate analog on African trypanosomes by Bacchi, Cyrus J, Goldberg, Burt, Rattendi, Donna, Gorrell, Thomas E, Spiess, Arthur J, Sufrin, Janice R

“…The effects of 5′-deoxy-5′-(hydroxyethylthio)adenosine (HETA), a trypanocidal analog of 5′-deoxy-5′-(methylthio)adenosine (MTA), on polyamine synthesis and…”
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Targeting 5'-deoxy-5'-(methylthio)adenosine phosphorylase by 5'-haloalkyl analogs of 5'-deoxy-5'-(methylthio)adenosine by Sufrin, Janice R, Spiess, Arthur J, Kramer, Debora L, Libby, Paul R, Miller, John T, Bernacki, Ralph J, Lee, Younha, Borchardt, Ronald T, Porter, Carl W

“…A series of 5'-haloalkyl-modified analogues of 5'-deoxy-5'-(methylthio)adenosine (MTA), a nucleoside byproduct of polyamine biosynthesis, has been synthesized:…”
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Synthesis and antiproliferative effects of novel 5'-fluorinated analogs of 5'-deoxy-5'-(methylthio)adenosine [Erratum to document cited in CA110(21):193314b] by Sufrin, Janice R, Spiess, Arthur J, Kramer, Debora L, Libby, Paul R, Porter, Carl W

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In vivo efficacies of 5'-methylthioadenosine analogs as trypanocides by BACCHI, C. J, SANABRIA, K, SPIESS, A. J, VARGAS, M, MARASCO, C. J, JIMENEZ, L. M, GOLDBERG, B, SUFRIN, J. R

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Antitrypanosomal activity of purine nucleosides can be enhanced by their conversion to O-acetylated derivatives by Sufrin, J R, Rattendi, D, Spiess, A J, Lane, S, Marasco, Jr, C J, Bacchi, C J

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Purine 2′, 3′-acyclonucleosides: Improved synthesis and antiparasitic actimity by Sufrin, Janice R., Spiess, Arthur J., Marasco, Canio J., Croft, Simon L., Snowdon, Diane, Yardley, Vanessa, Bacchi, Cyrus J

“…Synthesis of purine 2′,3′-acyclonucleosides has been improved by using methanol as solvent for sequential oxidation/reduction reactions on periodate- and…”
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Identification of 8, 9-dihydro-8, 9-dihydroxy-7, 12-dimethylbenz(a)anthracene as a rat liver metabolite of 7, 12-dimethylbenz(a) anthracene by Morreal, C E, Alks, V, Spiess, A J

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