Search Results - "Spiekerkoetter, E"

Goal-oriented treatment and combination therapy for pulmonary arterial hypertension by Hoeper, M. M, Markevych, I, Spiekerkoetter, E, Welte, T, Niedermeyer, J

“…Combination therapy may improve outcome in patients with severe pulmonary arterial hypertension (PAH). PAH patients were treated according to a goal-oriented…”
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Experience with inhaled iloprost and bosentan in portopulmonary hypertension by Hoeper, M. M, Seyfarth, H. J, Hoeffken, G, Wirtz, H, Spiekerkoetter, E, Pletz, M. W, Welte, T, Halank, M

“…Novel treatments, such as prostanoids or endothelin receptor antagonists, have been introduced for various forms of pulmonary arterial hypertension, but the…”
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Targeted Immune and Growth Factor Proteomics of Right Heart Adaptation to Pulmonary Arterial Hypertension Reveals a Potential Role of the Hepatic Growth Factor by Amsallem, M., Sweatt, A.J., Arthur Ataam, J., Mercier, O., Lecerf, F., Rucker-Martin, C., Ghigna, M., Spiekerkoetter, E., Rabinovitch, M., Kuznetsova, T., Fadel, E., Haddad, F., Zamanian, R.

“…Although inflammatory features have been reported in the pressure-overloaded right ventricle, prior proteomic studies of pulmonary arterial hypertension (PAH)…”
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Treatment with low-dose tacrolimus inhibits bleeding complications in a patient with hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension by Sommer, N, Droege, F, Gamen, KE, Geisthoff, U, Gall, H, Tello, K, Richter, MJ, Deubner, LM, Schmiedel, R, Hecker, M, Spiekerkoetter, E, Wirsching, K, Seeger, W, Ghofrani, HA, Pullamsetti, S

“…Pulmonary arterial hypertension (PAH) can be found in patients suffering from a loss-of-function mutation of the gene encoding for the activin receptor-like…”
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Bosentan treatment in patients with primary pulmonary hypertension receiving nonparenteral prostanoids by Hoeper, M.M, Taha, N, Bekjarova, A, Gatzke, R, Spiekerkoetter, E

“…Primary pulmonary hypertension (PPH) is a life-threatening disease. Nonparenteral prostanoids, i.e. aerosolised iloprost or oral beraprost sodium show…”
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837 Echocardiographic and Clinical Predictors of Outcome in Patients with Pulmonary Arterial Hypertension by Haddad, F, Doyle, R, Denault, A.Y, Skhiri, M, Spiekerkoetter, E, de Jesus Perez, V, Kudelko, K, Schnittger, I, Zamanian, R

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19 Utility of Changes in Heart Rate and Blood Pressure during Six Minute Walk Test as Predictors of Outcomes in Pulmonary Arterial Hypertension by Saito, S, Haddad, F, Skhiri, M, Hsi, A, Spiekerkoetter, E, de Jesus Perez, V, Kudelko, K, Zamanian, R.T

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127: Characterization of Patients with Drugs and Toxins Associated Pulmonary Arterial Hypertension: A Clinical and Outcomes Perspective by Snook, S, Kudelko, K, Spiekerkoetter, E, Fuh, E, Haddad, F, Zamanian, R.T

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Intravenous iloprost for treatment failure of aerosolised iloprost in pulmonary arterial hypertension by Hoeper, M.M, Spiekerkoetter, E, Westerkamp, V, Gatzke, R, Fabel, H

“…Treatment with aerosolised iloprost, a prostacyclin analogue, has beneficial effects in patients with pulmonary arterial hypertension (PAH). It is unclear if…”
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Effects of inhaled salbutamol in primary pulmonary hypertension by Spiekerkoetter, E, Fabel, H, Hoeper, M.M

“…Although lung function is grossly normal in patients with primary pulmonary hypertension (PPH), mild-to-moderate peripheral airflow obstruction can be found in…”
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C27 NEONATAL AND PEDIATRIC CRITICAL CARE: Fk506 Restores Reduced Bmp Signaling In The Lung Of Mechanically Ventilated Newborn Mice by Koschlig, M, Tian, X, Sudheendra, D, Spiekerkoetter, E, Hilgendorff, A

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B52 NEONATAL LUNG DISEASE: FROM BENCH TO BABIES: Enhanced Effects Of Hyperoxia On Vessel Development In Newborn Mice Heterozygote For The Bmp Receptor 2 by Koschlig, M, Tian, X, Sudheendra, D, Spiekerkoetter, E F, Hilgendorff, A

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B96 HUNGRY HEART: RV FUNCTION IN PH: Fk506 Reduces Right Ventricular Cardiac Fibrosis In A Bmp Dependent Manner by Spiekerkoetter, E F, Tian, X, Kuang, J, Sudheendra, D, Reddy, S, Zhao, M, Bernstein, D

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A67 BREAKDOWN: THE CELLULAR CONTRIBUTION TO PULMONARY HYPERTENSION: Lymphocyte Specific Protein Tyrosine Kinase (lck), A Novel Bmpr2 Modulator, Validated By In Situ Transcriptome Profiling by Andruska, A M, Dannewitz, S, Sudheendra, D, Tian, X, Nagendran, M, Spiekerkoetter, E F, Harbury, P, Desai, T

“…[...]the technique was applied to normal human lung tissue. Conclusions: We have developed a tool to determine the spatial localization of expression of…”
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C27 LET'S PRETEND WE'RE MARRIED: THE RIGHT VENTRICLE AND THE PULMONARY VASCULATURE: Reduced Bmpr2 Signaling Impairs Right Ventricular Heart Function And Exaggerates Cardiac Fibrosis Upon Chronic Pressure Overload by Boehm, M, Tian, X, Zhao, M, Dannewitz, S, Kuramoto, K, Kuang, J, Reddy, S, Bernstein, D, Ashley, E, Spiekerkoetter, E

“…Whether reduced BMPR2 signaling is cause or consequence in heart failure pathogenesis is unclear. [...]we sought to investigate RV structure and function in…”
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A67 BREAKDOWN: THE CELLULAR CONTRIBUTION TO PULMONARY HYPERTENSION: Hypoxia Inducible Factor-1α Increases Bone Morphogenetic Protein Receptor 2 Signaling In Pulmonary Artery Endothelial Cells (paecs) by Kuang, J, Tian, X, Prosseda, S Dannewitz, Tian, A, Cornfield, D, Nicolls, M R, Spiekerkoetter, E F

“…While the role of HIF-1a on BMPR2 signaling is most likely cell specific, in endothelial cells, overexpression of HIF-1a has been associated with microvascular…”
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Prevalence of Malignancies After Lung Transplantation by Spiekerkoetter, E., Krug, N., Hoeper, M., Wiebe, K., Hamm, M., Harringer, W., Haverich, A., Fabel, H.

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A51 EXPERIMENTAL MODELS OF PULMONARY HYPERTENSION: Hypoxia Inducible Factor-1[alpha] Increases Bone Morphogenetic Protein Signaling In Pulmonary Artery Endothelial Cells by Kuang, J, Tian, X, Tian, A, Semenza, G, Nicolls, M R, Spiekerkoetter, E

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D19 CLINICAL STUDIES IN PH: Serial Vasoreactivity Reassessment Is A Prognostic Tool In Pulmonary Arterial Hypertension by Sweatt, A J, Spiekerkoetter, E F, Hsi, A, Sung, Y, Perez, V De Jesus, Kudelko, K, Zamanian, R T

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B55 REASON TO BELIEVE: CLINICAL PH STUDIES: Using Near-Infrared Spectroscopy To Characterize The Effects Of Inhaled Nitric Oxide On Skeletal Muscle Oxygen Saturation In Adults With Pulmonary Arterial Hypertension by Shaller, B D, Kholdani, C, Hedlin, H, Sweatt, A J, Hsi, A, Spiekerkoetter, E F, Zamanian, R T

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