Search Results - "Spickett, G P"

Immune deficiency disorders involving neutrophils by Spickett, G P

“…This review addresses current thinking on the diagnosis, causation and management of common and rare primary disorders of granulocytes. The genetic basis of…”
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Immunodeficiency and Autoimmunity in 22q11.2 Deletion Syndrome by McLean-Tooke, A, Spickett, G.P, Gennery, A.R

“…22q11.2 deletion syndrome is the commonest chromosome deletion syndrome. 22q11.2 deletion may result in variable clinical phenotypes which may differ even…”
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Current perspectives on common variable immunodeficiency (CVID) by Spickett, G. P.

“…Common variable immunodeficiency (CVID) is the commonest symptomatic primary antibody deficiency syndrome, and Scandinavian data suggest a prevalence of 1 per…”
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Impaired dendritic cell maturation and cytokine production in patients with chronic mucocutanous candidiasis with or without APECED by Ryan, K. R., Hong, M., Arkwright, P. D., Gennery, A. R., Costigan, C., Dominguez, M., Denning, D., McConnell, V., Cant, A. J., Abinun, M., Spickett, G. P., Lilic, D.

“…Summary Patients with chronic mucocutaneous candidiasis (CMC) suffer persistent infections with the yeast Candida. CMC includes patients with autoimmune…”
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Lymphoproliferative disease in antibody deficiency: a multi‐centre study by GOMPELS, M. M., HODGES, E., LOCK, R. J., ANGUS, B., WHITE, H., LARKIN, A., CHAPEL, H. M., SPICKETT, G. P., MISBAH, S. A., SMITH, J. L.

“…SUMMARY We have undertaken a retrospective study of antibody deficient patients, with and without lymphoma, and assessed the ability of specific polymerase…”
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Does this patient with urticaria/angioedema have anaphylaxis? by Spickett, GP, Stroud, C

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T cell receptor Vβ repertoire of T lymphocytes and T regulatory cells by flow cytometric analysis in healthy children by McLean-Tooke, A, Barge, D, Spickett, G.P, Gennery, A.R

“…Evaluation of the T cell receptor (TCR) Vβ repertoire by flow cytometric analysis has been used for studying the T cell compartments for diseases in which T…”
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The comparison of the efficacy and safety of intravenous versus subcutaneous immunoglobulin replacement therapy by Chapel, H M, Spickett, G P, Ericson, D, Engl, W, Eibl, M M, Bjorkander, J

“…To compare the efficacy of immunoglobulin replacement therapy given intravenously versus subcutaneously to prevent infections in patients with primary antibody…”
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Lymphocyte subsets in term and significantly preterm UK infants in the first year of life analysed by single platform flow cytometry by Berrington, J. E., Barge, D., Fenton, A. C., Cant, A. J., Spickett, G. P.

“…Summary This observational study describes the ranges observed for lymphocyte subsets for significantly preterm infants (<32 weeks) in the first year of life,…”
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Pattern recognition receptor expression is not impaired in patients with chronic mucocutanous candidiasis with or without autoimmune polyendocrinopathy candidiasis ectodermal dystrophy by Hong, M, Ryan, K.R, Arkwright, P.D, Gennery, A.R, Costigan, C, Dominguez, M, Denning, D.W, McConnell, V, Cant, A.J, Abinun, M, Spickett, G.P, Swan, D.C, Gillespie, C.S, Young, D.A, Lilic, D

“…Patients with chronic mucocutaneous candidiasis (CMC) have an unknown primary immune defect and are unable to clear infections with the yeast Candida. CMC…”
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Anhidrotic ectodermal dysplasia and immunodeficiency: the role of NEMO by Carrol, E D, Gennery, A R, Flood, T J, Spickett, G P, Abinun, M

“…Anhidrotic (hypohidrotic) ectodermal dysplasia associated with immunodeficiency (EDA-ID; OMIM 300291) is a newly recognised primary immunodeficiency caused by…”
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Methotrexate, rheumatoid arthritis and infection risk—what is the evidence? by McLean-Tooke, Andrew, Aldridge, Catherine, Waugh, Sheila, Spickett, Gavin P., Kay, Lesley

“…Low-dose MTX administered weekly remains a mainstay in the therapy of RA. There is a belief amongst rheumatologists that RA patients taking MTX have both an…”
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Best practice in primary care pathology: review 6 by Smellie, W S A, Forth, J, Coleman, J J, Irvine, W, Dore, P C, Handley, G, Williams, D G, Galloway, P J, Kerr, K G, Herriot, R, Spickett, G P, Reynolds, T M

“…This sixth best practice review examines four series of common primary care questions in laboratory medicine: (1) laboratory monitoring in hypertension and…”
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Best practice in primary care pathology: review 2 by Smellie, W S, Forth, J O, McNulty, C A M, Hirschowitz, L, Lilic, D, Gosling, R, Bareford, D, Logan, E, Kerr, K G, Spickett, G P, Hoffman, J, Galloway, A, Bloxham, C A

“…This second best practice review examines five series of common primary care questions in laboratory medicine: (1) laboratory testing for allergy, (2)…”
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Northern region asplenia register--analysis of first two years by Spickett, G P, Bullimore, J, Wallis, J, Smith, S, Saunders, P

“…OBJECTIVES: To assess the feasibility of setting up a register of patients with asplenia within a defined geographical area; to ensure that guidelines on best…”
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Scedosporium apiospermum in chronic granulomatous disease treated with an HLA matched bone marrow transplant by Gompels, M M, Bethune, C A, Jackson, G, Spickett, G P

“…A patient with chronic granulomatous disease who was being treated with steroids was diagnosed with a soft tissue Scedosporium apiospermum infection. Despite…”
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Chronic mucocutaneous candidiasis. I. Altered antigen‐stimulated IL‐2, IL‐4, IL‐6 and interferon‐gamma (IFN‐γ) production by LILIC, D., CANT, A. J., ABINUN, M., CALVERT, J. E., SPICKETT, G. P.

“…Patients with chronic mucocutaneous candidiasis (CMC) present with persistent infections with the opportunistic yeast Candida. Impaired cell‐mediated responses…”
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Survey of infection in patients receiving antibody replacement treatment for immune deficiency by Pettit, S J, Bourne, H, Spickett, G P

“…Background:0 Primary antibody deficiency disorders are a heterogeneous group of disorders, which are treated by regular infusions of immunoglobulin. Despite…”
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Flow Cytometric Analysis of TCR Vβ Repertoire in Patients with 22q11.2 Deletion Syndrome by McLean‐Tooke, A., Barge, D., Spickett, G. P., Gennery, A. R.

“…In 22q11.2 deletion patients, the normal decrease in T lymphocyte counts after 1–2 years is blunted such that relatively T lymphocyte numbers increase over…”
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Chronic enteroviral meningoencephalitis in agammaglobulinemia : case report and literature review by MISBAH, S. A, SPICKETT, G. P, RYBA, P. C. J, HOCKADAY, J. M, KROLL, J. S, SHERWOOD, C, KURTZ, J. B, MOXON, E. R, CHAPEL, H. M

“…Chronic enteroviral meningoencephalitis is a well-recognized complication in patients with X-linked agammaglobulinemia (XLA). The majority of published cases…”
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