Search Results - "Sperlongano, Pasquale"
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Mitochondria as playmakers of apoptosis, autophagy and senescence
Published in Seminars in cell & developmental biology (01-02-2020)“…Mitochondria are the key energy-producing organelles and cellular source of reactive species. They are responsible for managing cell life and death by a…”
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2
Molecular targets and oxidative stress biomarkers in hepatocellular carcinoma: an overview
Published in Journal of translational medicine (10-10-2011)“…Hepatocellular carcinoma (HCC) is a complex and heterogeneous tumor with multiple genetic aberrations. Several molecular pathways involved in the regulation of…”
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3
Silybin-Induced Apoptosis Occurs in Parallel to the Increase of Ceramides Synthesis and miRNAs Secretion in Human Hepatocarcinoma Cells
Published in International journal of molecular sciences (03-05-2019)“…Silybin is a flavonolignan extracted from (milk thistle) with hepatoprotective, antioxidant, and anti-inflammatory activity. Several studies have shown that…”
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4
Systemic inflammatory status at baseline predicts bevacizumab benefit in advanced non-small cell lung cancer patients
Published in Cancer biology & therapy (10-06-2013)“…Bevacizumab is a humanized anti-VEGF monoclonal antibody able to produce clinical benefit in advanced non-squamous non-small-cell lung cancer (NSCLC) patients…”
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Single nucleotide polymorphisms of ABCC5 and ABCG1 transporter genes correlate to irinotecan-associated gastrointestinal toxicity in colorectal cancer patients: A DMET microarray profiling study
Published in Cancer biology & therapy (01-11-2011)“…Recent findings have disclosed the role of UDP-glucuronosyltransferase (UGT) 1A1*28 on the haematological toxicity induced by irinotecan (CPT-11), a drug…”
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6
Surgical Treatment of Intrathyroid Metastases: Preliminary Results of a Multicentric Study
Published in Anticancer research (01-09-2008)“…Background: Intrathyroid metastases (ITM) are rare and usually have a dismal prognosis. The aim of this study was to detect which neoplasms metastasize most…”
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Immune-modulating Effects of the Newest Cetuximab-based Chemoimmunotherapy Regimen in Advanced Colorectal Cancer Patients
Published in Journal of immunotherapy (1997) (01-06-2012)“…Cetuximab is a human-murine chimeric monoclonal antibody to the epidermal growth factor receptor, active for advanced colorectal cancer treatment in…”
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Anaplastic lymphoma kinase: a glimmer of hope in lung cancer treatment?
Published in Expert review of anticancer therapy (01-04-2013)“…Anaplastic lymphoma kinase (ALK) rearrangements (ALK-Rs) have been identified in 3-7% of all non-small-cell lung cancers (NSCLCs) and represent an important…”
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Type I interferons: ancient peptides with still under-discovered anti-cancer properties
Published in Protein and peptide letters (01-04-2013)“…Type I interferons (IFNs) represent a group of cytokines that act through a common receptor composed by two chains (IFNAR-1 and IFNAR-2). Several in vitro and…”
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Dose/dense metronomic chemotherapy with fractioned cisplatin and oral daily etoposide enhances the anti-angiogenic effects of bevacizumab in advanced non-small-cell-lung cancer patients
Published in Cancer biology & therapy (01-05-2010)“…Background: We designed a translational clinical trial to investigate whether a dose/dense chemotherapy regimen is able to enhance in patients with…”
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Hepaticojejunostomy in the treatment of iatrogenic biliary lesions following laparoscopic cholecystectomy. A retrospective study on 51 cases
Published in Hepato-gastroenterology (01-12-2007)“…Laparoscopic cholecystectomy is characterized by a higher incidence of iatrogenic biliary lesions. The Authors evaluate the role of hepaticojejunostomy in the…”
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12
Carcinogenetic mechanisms of endocrine disruptors in female cancers (Review)
Published in Oncology reports (01-08-2016)“…Endocrine disruptors (EDs) are pollutants that alter the endocrine system and are involved in carcinogenesis. EDs have multiple and complex levels of action…”
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13
Short-Term Diet and Moderate Exercise in Young Overweight Men Modulate Cardiocyte and Hepatocarcinoma Survival by Oxidative Stress
Published in Oxidative medicine and cellular longevity (2014)“…The present study was designed to evaluate the effects of diet lifestyle on extending lifespan and reducing liver cancer risk. Young overweight men (n=20),…”
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Clinical and pathological factors predictive of response to neoadjuvant chemotherapy in breast cancer: A single center experience
Published in Oncology letters (01-10-2019)“…Neoadjuvant chemotherapy (NAC) of breast cancer (BC) improves outcomes, especially in patients with locally advanced and inflammatory cancer. Further insight…”
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Role of perineural invasion as a prognostic factor in laryngeal cancer
Published in Oncology letters (01-04-2016)“…The diffusion of laryngeal cancer cells in the perineural space is a parameter associated with a negative prognosis, high loco-regional recurrence and low…”
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Protracted low dose of oral vinorelbine and temozolomide with whole-brain radiotherapy in the treatment for breast cancer patients with brain metastases
Published in Cancer chemotherapy and pharmacology (01-10-2012)“…Purpose The management of brain metastases (BM) from breast cancer (BC) needs to be improved, and new therapeutic strategies are urgently requested. In this…”
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Sorafenib in elderly patients with advanced hepatocellular carcinoma: a case series
Published in Oncology (01-01-2013)“…The management of hepatocellular carcinoma (HCC) in elderly patients is significantly more complicated than in younger patients because of medical…”
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18
Percutaneous Ethanol Injection of Hyperfunctioning Thyroid Nodules: Long-Term Follow-Up in 125 Patients
Published in American journal of roentgenology (1976) (01-03-2008)“…The purpose of this study was to assess the long-term efficacy of percutaneous ethanol injection (PEI) for the treatment of hyperfunctioning thyroid nodules…”
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19
Postoperative hypocalcemia: Assessment timing
Published in International journal of surgery (London, England) (01-08-2014)“…Abstract 180 total thyroidectomy case studies performed by the same operator in the years 2006–2010, all done with sutureless technique (Ligasure precise® )…”
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Prognosis of patients with spontaneous rupture of hepatocellular carcinoma in cirrhosis
Published in Updates in surgery (01-03-2011)“…The treatment of cirrhotic patients with spontaneous rupture of hepatocellular carcinoma (HCC) is controversial and largely dependent on general conditions of…”
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