Search Results - "Spengler, R. N."

Biomolecular characterization of 3500-year-old ancient Egyptian mummification balms from the Valley of the Kings by Huber, B., Hammann, S., Loeben, C. E., Jha, D. K., Vassão, D. G., Larsen, T., Spengler, R. N., Fuller, D. Q., Roberts, P., Devièse, T., Boivin, N.

“…Ancient Egyptian mummification was practiced for nearly 4000 years as a key feature of some of the most complex mortuary practices documented in the…”
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An antidepressant mechanism of desipramine is to decrease tumor necrosis factor-α production culminating in increases in noradrenergic neurotransmission by Reynolds, J.L., Ignatowski, T.A., Sud, R., Spengler, R.N.

“…The monoamine theory of depression proposes decreased bioavailability of monoamines, such as norepinephrine (NE), as the underlying cause of depression. Thus,…”
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Resident cardiac mast cells degranulate and release preformed TNF-α, initiating the cytokine cascade in experimental canine myocardial ischemia/reperfusion by FRANGOGIANNIS, N. G, LINDSEY, M. L, MICHAEL, L. H, YOUKER, K. A, BRESSLER, R. B, MENDOZA, L. H, SPENGLER, R. N, SMITH, C. W, ENTMAN, M. L

“…Neutrophil-induced cardiomyocyte injury requires the expression of myocyte intercellular adhesion molecule (ICAM)-1 and ICAM-1-CD11b/CD18 adhesion. We have…”
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Endogenous norepinephrine regulates tumor necrosis factor-alpha production from macrophages in vitro by Spengler, RN, Chensue, SW, Giacherio, DA, Blenk, N, Kunkel, SL

“…Evidence for the extraneuronal accumulation of norepinephrine has been demonstrated to occur in macrophage (M phi), yet the physiologic role of this system…”
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Stimulation of alpha-adrenergic receptor augments the production of macrophage-derived tumor necrosis factor by Spengler, RN, Allen, RM, Remick, DG, Strieter, RM, Kunkel, SL

“…Accumulating evidence supports the hypothesis that neuroendocrine hormones may participate in immunologic processes. In our study we have determined that…”
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Brain-derived TNFα mediates neuropathic pain by Ignatowski, Tracey A, Covey, William C, Knight, Paul R, Severin, Charles M, Nickola, Tracey J, Spengler, Robert N

“…Neuropathic pain is a chronic pain state that develops a central component following acute nerve injury. However, the pathogenic mechanisms involved in the…”
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Brain-derived TNFα: involvement in neuroplastic changes implicated in the conscious perception of persistent pain by Covey, William C, Ignatowski, Tracey A, Knight, Paul R, Spengler, Robert N

“…The pleiotropic cytokine tumor necrosis factor-alpha (TNFα) is implicated in the development of persistent pain through its actions in the periphery and in the…”
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Medieval mortuary millet: Micro and macrobotanical evidence from an early Turkic burial in the Altai by Ryabogina, N.E., Soenov, V.I., Spengler, R.N., Konstantinov, N.A., Afonin, A.S., Slepchenko, S.M.

“…While early Turkic populations of northern Central Asia are traditionally thought to have been specialized nomads, over the past few years archaeological…”
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Cellular and molecular regulation of tumor necrosis factor-alpha production by pentoxifylline by Strieter, R M, Remick, D G, Ward, P A, Spengler, R N, Lynch, 3rd, J P, Larrick, J, Kunkel, S L

“…Tumor necrosis factor-alpha (TNF), a mononuclear phagocyte (MO)-derived peptide, is increasingly being recognized for its pleomorphic immunologic effects. A…”
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Dynamics of dibutyryl cyclic AMP- and prostaglandin E2-mediated suppression of lipopolysaccharide-induced tumor necrosis factor alpha gene expression by SPENGLER, R. N, SPENGLER, M. L, LINCOLN, P, REMICK, D. G, STRIETER, R. M, KUNKEL, S. L

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Tumor necrosis factor-alpha: presynaptic sensitivity is modified after antidepressant drug administration by Ignatowski, T A, Spengler, R N

“…Presynaptic adrenergic functioning was coupled to cytokine sensitivity in order to further establish the mechanism of action of a tricyclic antidepressant…”
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Streptococcal Histone Induces Murine Macrophages To Produce Interleukin-1 and Tumor Necrosis Factor Alpha by LIPING ZHANG, IGNATOWSKI, T. A, SPENGLER, R. N, NOBLE, B, STINSON, M. W

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Modulation of tumor necrosis factor-alpha gene expression. Desensitization of prostaglandin E2-induced suppression by Spengler, RN, Spengler, ML, Strieter, RM, Remick, DG, Larrick, JW, Kunkel, SL

“…PGE2, an immune mediator, is an inhibitor of LPS-stimulated TNF production and gene transcription. In the present study we determined whether pretreatment with…”
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Tumor necrosis factor expressed by primary hippocampal neurons and SH-SY5Y cells is regulated by alpha(2)-adrenergic receptor activation by Renauld, A E, Spengler, R N

“…Neuron expression of the cytokine tumor necrosis factor-alpha (TNF), and the regulation of the levels of TNF by alpha(2)-adrenergic receptor activation were…”
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The dissipation of neuropathic pain paradoxically involves the presence of tumor necrosis factor-α (TNF) by Ignatowski, Tracey A., Sud, Reeteka, Reynolds, Jessica L., Knight, Paul R., Spengler, Robert N.

“…Neuropathic pain, a chronic disabling pain arising from nerve injury, develops a central component. In brain neurons, tumor necrosis factor-α (TNF) levels…”
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Antidepressant drug-induced alterations in neuron-localized tumor necrosis factor-alpha mRNA and alpha(2)-adrenergic receptor sensitivity by Nickola, T J, Ignatowski, T A, Reynolds, J L, Spengler, R N

“…The pleiotropic cytokine tumor necrosis factor-alpha (TNF) and alpha(2)-adrenergic receptor activation regulate norepinephrine (NE) release from neurons in the…”
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Amitriptyline administration transforms tumor necrosis factor-alpha regulation of norepinephrine release in the brain by Reynolds, Jessica L., Ignatowski, Tracey A., Gallant, Samuel, Spengler, Robert N.

“…The present study demonstrates that the mixed action antidepressant drug amitriptyline enhances norepinephrine (NE) release by transforming the nature of the…”
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Clonidine suppresses plasma and cerebrospinal fluid concentrations of TNF-alpha during the perioperative period by Nader, N D, Ignatowski, T A, Kurek, C J, Knight, P R, Spengler, R N

“…The analgesic properties of alpha(2)-agonists are well known. In experimental models, tumor necrosis factor (TNF)-alpha regulates adrenergic responses in the…”
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Neuronal-associated tumor necrosis factor (TNF α): its role in noradrenergic functioning and modification of its expression following antidepressant drug administration by Ignatowski, Tracey A, Noble, Bernice K, Wright, John R, Gorfien, Janet L, Heffner, Reid R, Spengler, Robert N

“…Tumor necrosis factor-alpha (TNF α) and the α 2-adrenergic agonist clonidine regulate norepinephrine (NE) release from noradrenergic nerve terminals in the…”
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Seeing the wood for the trees: active human–environmental interactions in arid northwestern China by Shen, Hui, Spengler, Robert N, Zhou, Xinying, Betts, Alison, Jia, Peter Weiming, Zhao, Keliang, Li, Xiaoqiang

“…Due largely to demographic growth, agricultural populations during the Holocene became increasingly more impactful ecosystem engineers. Multidisciplinary…”
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