Search Results - "Spender, L.C."

Melanoma secretion of transforming growth factor‐β2 leads to loss of epidermal AMBRA1 threatening epidermal integrity and facilitating tumour ulceration by Cosgarea, I., McConnell, A.T., Ewen, T., Tang, D., Hill, D.S., Anagnostou, M., Elias, M., Ellis, R.A., Murray, A., Spender, L.C., Giglio, P., Gagliardi, M., Greenwood, A., Piacentini, M., Inman, G.J., Fimia, G.M., Corazzari, M., Armstrong, J.L., Lovat, P.E.

“…Summary Background For patients with early American Joint Committee on Cancer (AJCC)‐stage melanoma the combined loss of the autophagy regulatory protein…”
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Fatal attractions? Correlations of CXCL12-CXCR4-CXCR7 expression with disease progression in melanoma and Kaposi sarcoma by Spender, L.C., Inman, G.J.

“…Linked Article: McConnell et al. Br J Dermatol 2016; 175:1210–1220. Linked Article: Desnoyer et al. Br J Dermatol 2016; 175: 1251–1262…”
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An investigation of the clinical impact and therapeutic relevance of a DNA damage immune response (DDIR) signature in patients with advanced gastroesophageal adenocarcinoma by Baxter, M.A., Spender, L.C., Cairns, D., Walsh, S., Oparka, R., Porter, R.J., Bray, S., Skinner, G., King, S., Turbitt, J., Collinson, D., Miedzybrodzka, Z.H., Jellema, G., Logan, G., Kennedy, R.D., Turkington, R.C., McLean, M.H., Swinson, D., Grabsch, H.I., Lord, S., Seymour, M.J., Hall, P.S., Petty, R.D.

“…An improved understanding of which gastroesophageal adenocarcinoma (GOA) patients respond to both chemotherapy and immune checkpoint inhibitors (ICI) is…”
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TGF-β-mediated activation of RhoA signalling is required for efficient HaRas and BRAF transformation by Fleming, Y M, Ferguson, G J, Spender, L C, Larsson, J, Karlsson, S, Ozanne, B W, Grosse, R, Inman, G J

“…Transforming growth factor beta-1 (TGF-beta) acts as both a tumour suppressor and a tumour promoter in a context-dependent manner. The tumour-promoting…”
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