Search Results - "Spencer, Y."
-
1
The Warburg Effect, Lactate, and Nearly a Century of Trying to Cure Cancer
Published in Seminars in nephrology (01-07-2019)“…Nearly 100 years ago, Otto Warburg undertook a study of tumor metabolism, and discovered increased lactate caused by increased glycolysis in cancer cells. His…”
Get full text
Journal Article -
2
Overreaction in Expectations: Evidence and Theory
Published in The Quarterly journal of economics (01-08-2023)“…Abstract We investigate biases in expectations across different settings through a large-scale randomized experiment where participants forecast stable…”
Get full text
Journal Article -
3
The Basic Biology of Redoxosomes in Cytokine-Mediated Signal Transduction and Implications for Disease-Specific Therapies
Published in Biochemistry (Easton) (18-03-2014)“…Redox reactions have been established as major biological players in many cellular signaling pathways. Here we review mechanisms of redox signaling with an…”
Get full text
Journal Article -
4
Memory and Probability
Published in The Quarterly journal of economics (01-02-2023)“…Abstract In many economic decisions, people estimate probabilities, such as the likelihood that a risk materializes or that a job applicant will be a…”
Get full text
Journal Article -
5
Linagliptin unmasks specific antioxidant pathways protective against albuminuria and kidney hypertrophy in a mouse model of diabetes
Published in PloS one (06-07-2018)“…Dipeptidyl peptidase-4 (DPP-4) inhibitors may have protective effects on diabetic kidney disease (DKD) via specific antioxidant pathways. The DPP-4 inhibitor,…”
Get full text
Journal Article -
6
Malaria parasites utilize two essential plasma membrane fusogens for gamete fertilization
Published in Cellular and molecular life sciences : CMLS (01-11-2022)“…Cell fusion of female and male gametes is the climax of sexual reproduction. In many organisms, the Hapless 2 (HAP2) family of proteins play a critical role in…”
Get full text
Journal Article -
7
A large-scale chromosomal inversion is not associated with life history development in rainbow trout from Southeast Alaska
Published in PloS one (20-09-2019)“…In studying the causative mechanisms behind migration and life history, the salmonids-salmon, trout, and charr-are an exemplary taxonomic group, as life…”
Get full text
Journal Article -
8
An exploratory study to characterize the HIV testing-to-care continuum to improve outcomes for Black and Latinx residents of South Los Angeles
Published in PloS one (30-08-2022)“…South Los Angeles (SPA6), with mostly Black (27.4%) and Latinx (68.2%) residents, has the second highest rates of new HIV diagnoses (31 per 100,000) in Los…”
Get full text
Journal Article -
9
Gill raker and pyloric caeca counts differ between Arctic char (Salvelinus alpinus) and Dolly Varden (S. malma) populations across their ranges
Published in Journal of fish biology (01-10-2024)“…Meristic characters are often used to differentiate between closely related forms, morphs, and species of fishes, and lend insight into ecology and…”
Get full text
Journal Article -
10
PfARID Regulates P. falciparum Malaria Parasite Male Gametogenesis and Female Fertility and Is Critical for Parasite Transmission to the Mosquito Vector
Published in mBio (28-06-2022)“…Sexual reproduction of Plasmodium falciparum parasites is critical to the spread of malaria in the human population. The factors that regulate gene expression…”
Get full text
Journal Article -
11
An Epidemiological Investigation of a Sustained High Rate of Pediatric Parapneumonic Empyema: Risk Factors and Microbiological Associations
Published in Clinical infectious diseases (15-02-2002)“…We investigated the increasing incidence of pediatric empyema during the 1990s at Primary Children's Medical Center in Salt Lake City. Of 540 children…”
Get full text
Journal Article -
12
An updated review of the post-glacial history, ecology, and diversity of Arctic char (Salvelinus alpinus) and Dolly Varden (S. malma)
Published in Environmental biology of fishes (2024)“…Arctic char ( Salvelinus alpinus ) and Dolly Varden ( S . malma ) are two closely related species in the genus Salvelinus . Both species show substantial…”
Get full text
Journal Article -
13
Effects of Aging on Identifying Emotions Conveyed by Point-Light Walkers
Published in Psychology and aging (01-02-2016)“…The visual system is able to recognize human motion simply from point lights attached to the major joints of an actor. Moreover, it has been shown that younger…”
Get full text
Journal Article -
14
A replication-competent late liver stage-attenuated human malaria parasite
Published in JCI insight (09-07-2020)“…Whole-sporozoite vaccines engender sterilizing immunity against malaria in animal models and importantly, in humans. Gene editing allows for the removal of…”
Get full text
Journal Article -
15
A Humanized Mouse Model for Plasmodium vivax to Test Interventions that Block Liver Stage to Blood Stage Transition and Blood Stage Infection
Published in iScience (21-08-2020)“…The human malaria parasite Plasmodium vivax remains vastly understudied, mainly due to the lack of suitable laboratory models. Here, we report a humanized…”
Get full text
Journal Article -
16
Control of Hepatic Nuclear Superoxide Production by Glucose 6-Phosphate Dehydrogenase and NADPH Oxidase-4
Published in The Journal of biological chemistry (18-03-2011)“…Redox-regulated signal transduction is coordinated by spatially controlled production of reactive oxygen species within subcellular compartments. The nucleus…”
Get full text
Journal Article -
17
A Malaria Parasite Cross Reveals Genetic Determinants of Plasmodium falciparum Growth in Different Culture Media
Published in Frontiers in cellular and infection microbiology (30-05-2022)“…What genes determine growth and nutrient utilization in asexual blood-stage malaria parasites? Competition experiments between NF54, clone 3D7, a lab-adapted…”
Get full text
Journal Article -
18
Pf ARID Regulates P. falciparum Malaria Parasite Male Gametogenesis and Female Fertility and Is Critical for Parasite Transmission to the Mosquito Vector
Published in mBio (28-06-2022)“…Sexual reproduction of Plasmodium falciparum parasites is critical to the spread of malaria in the human population. The factors that regulate gene expression…”
Get full text
Journal Article -
19
Inconsequential role for chemerin-like receptor 1 in the manifestation of ozone-induced lung pathophysiology in male mice
Published in Physiological reports (01-04-2024)“…We executed this study to determine if chemerin-like receptor 1 (CMKLR1), a G protein-coupled receptor expressed by leukocytes and non-leukocytes, contributes…”
Get full text
Journal Article -
20
The power and promise of genetic mapping from Plasmodium falciparum crosses utilizing human liver-chimeric mice
Published in Communications biology (14-06-2021)“…Genetic crosses are most powerful for linkage analysis when progeny numbers are high, parental alleles segregate evenly and numbers of inbred progeny are…”
Get full text
Journal Article