Search Results - "Spencer, T A"

Fitness costs of Cry1F resistance in fall armyworm, Spodoptera frugiperda by Vélez, A. M, Spencer, T. A, Alves, A. P, Crespo, A. L. B, Siegfried, B. D

“…Transgenic corn, Zea mays L., expressing the Bacillus thuringiensis Berliner (Bt) protein Cry1F has been registered for Spodoptera frugiperda (J. E. Smith)…”
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Inheritance of Resistance to the Cry1Ab Bacillus thuringiensis Toxin in Ostrinia nubilalis (Lepidoptera: Crambidae) by Alves, A. P., Spencer, T. A., Tabashnik, B. E., Siegfried, B. D.

“…Laboratory selection with Cry1Ab, the predominant Bacillus thuringiensis (Bt) toxin in transgenic corn, Zea mays L., produced >1000-fold resistance in two…”
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Sterol Efflux to Apolipoprotein A-I Originates from Caveolin-Rich Microdomains and Potentiates PDGF-Dependent Protein Kinase Activity by Fielding, P. E, Russel, J. S, Spencer, T. A, Hakamata, H, Nagao, K, Fielding, C. J

“…The kinetics of sterol efflux from human aortic smooth muscle cells equilibrated with a [3H]benzophenone-modified photoactivable free cholesterol analogue…”
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Inheritance of Cry1F resistance, cross-resistance and frequency of resistant alleles in Spodoptera frugiperda (Lepidoptera: Noctuidae) by Vélez, A M, Spencer, T A, Alves, A P, Moellenbeck, D, Meagher, R L, Chirakkal, H, Siegfried, B D

“…Transgenic maize, Zea maize L., expressing the Cry1F protein from Bacillus thuringiensis has been registered for Spodoptera frugiperda (J. E. Smith) control…”
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Fitness costs associated with Cry1F resistance in the European corn borer by Petzold‐Maxwell, J. L., Siegfried, B. D., Hellmich, R. L., Abel, C. A., Coates, B. S., Spencer, T. A., Horikoshi, R. J., Gassmann, A. J.

“…Crops producing insecticidal toxins derived from the bacterium Bacillus thuringiensis (Bt) are widely planted to manage insect pests. Bt crops can provide an…”
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Oxysterol regulators of 3-hydroxy-3-methylglutaryl-CoA reductase in liver. Effect of dietary cholesterol by SAUCIER, S. E, KANDUTSCH, A. A, GAYEN, A. K, SWAHN, D. K, SPENCER, T. A

“…Hepatic regulatory oxysterols were analyzed to determine which oxysterols were present in livers of mice fed a cholesterol-free diet and whether repression of…”
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Exploring the potential of neutron imaging for life sciences on IMAT by BURCA, G., NAGELLA, S., CLARK, T., TASEV, D., RAHMAN, I.A., GARWOOD, R.J., SPENCER, A.R.T., TURNER, M.J., KELLEHER, J.F.

“…Summary Neutron imaging has been employed in life sciences in recent years and has proven to be a viable technique for studying internal features without…”
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Efficiency enhancement of high power vacuum BWO's using nonuniform slow wave structures by Moreland, L.D., Schamiloglu, E., Lemke, W., Korovin, S.D., Rostov, V.V., Roitman, A.M., Hendricks, K.J., Spencer, T.A.

“…The Sinus-6, a high-power relativistic repetitively-pulsed electron beam accelerator, is used to drive various slow wave structures in a BWO configuration in…”
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Activation of the Nuclear Receptor LXR by Oxysterols Defines a New Hormone Response Pathway by Lehmann, Jürgen M., Kliewer, Steven A., Moore, Linda B., Smith-Oliver, Tracey A., Oliver, Beverly B., Su, Jui-Lan, Sundseth, Scott S., Winegar, Deborah A., Blanchard, Daniel E., Spencer, Thomas A., Willson, Timothy M.

“…Accumulation of cholesterol causes both repression of genes controlling cholesterol biosynthesis and cellular uptake and induction of cholesterol…”
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Validation of a novel resistance monitoring technique for corn rootworm (Coleoptera: Chrysomelidae) and event DAS-59122-7 maize by Nowatzki, T.M, Lefko, S.A, Binning, R.R, Thompson, S.D, Spencer, T.A, Siegfried, B.D

“…Rootworm control tactics have recently expanded to include transgenic maize, which express insecticidal proteins from Bacillus thuringiensis (Bt) to reduce…”
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Sterol-independent regulation of 3-hydroxy-3-methylglutaryl-CoA reductase by mevalonate in Chinese hamster ovary cells. Magnitude and specificity by PANINI, S. R, SCHNITZER-POLOKOFF, R, SPENCER, T. A, SINENSKY, M

“…In this paper, we assess the relative degree of regulation of the rate-limiting enzyme of isoprenoid biosynthesis, 3-hydroxy-3-methylglutaryl coenzyme A…”
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Identification of regulatory oxysterols, 24(S),25-epoxycholesterol and 25-hydroxycholesterol, in cultured fibroblasts by Saucier, S E, Kandutsch, A A, Taylor, F R, Spencer, T A, Phirwa, S, Gayen, A K

“…Biosynthetically tritiated sterols from Chinese hamster lung (Dede) cells were fractionated by high performance liquid chromatography, and fractions were…”
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ACAT-2, a second mammalian acyl-CoA:cholesterol acyltransferase. Its cloning, expression, and characterization by Cases, S. (University of California, San Francisco, CA.), Novak, S, Zheng, Y.W, Myers, H.M, Lear, S.R, Sande, E, Welch, C.B, Lusis, A.J, Spencer, T.A, Krause, B.R

“…The synthesis of cholesterol esters by acyl-CoA:cholesterol acyltransferase (ACAT, EC 2.3.1.26) is an important component of cellular cholesterol homeostasis…”
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24(S),25-Epoxycholesterol. Evidence consistent with a role in the regulation of hepatic cholesterogenesis by Spencer, T A, Gayen, A K, Phirwa, S, Nelson, J A, Taylor, F R, Kandutsch, A A, Erickson, S K

“…Previously we showed that 24(S),25-epoxycholesterol is formed from acetate, via squalene 2,3(S),22(S),23-dioxide and 24(S),25-oxidolanosterol, during the…”
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Accumulation of regulatory oxysterols, 32-oxolanosterol and 32-hydroxylanosterol in mevalonate-treated cell cultures by Saucier, S E, Kandutsch, A A, Phirwa, S, Spencer, T A

“…In a previous publication (Saucier, S.E., A.A., Taylor, F.R., Spencer, T.A., Phirwa, S., and Gayen, A.K., J. Biol. Chem. (1985) 260, 14571-14579), we…”
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Effects of specific inhibition of sterol biosynthesis on the uptake and utilization of low density lipoprotein cholesterol by HepG2 cells by Panini, SR, Everson, GT, Spencer, TA

“…Treatment of HepG2 cells in lipoprotein-deficient media with 4,4,10 beta-trimethyl-trans-decal-3 beta-ol (TMD) abolished the incorporation of [3H]acetate into…”
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24,25-Epoxysterol metabolism in cultured mammalian cells and repression of 3-hydroxy-3-methylglutaryl-CoA reductase by Taylor, F R, Kandutsch, A A, Gayen, A K, Nelson, J A, Nelson, S S, Phirwa, S, Spencer, T A

“…In view of the potential importance of 24,25-epoxysterols as intracellular regulators of 3-hydroxy-3-methylglutaryl-CoA reductase, the C-24 epimers of…”
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Pharmacophore Analysis of the Nuclear Oxysterol Receptor LXRα by Spencer, Thomas A, Li, Dansu, Russel, Jonathon S, Collins, Jon L, Bledsoe, Randy K, Consler, Thomas G, Moore, Linda B, Galardi, Cristin M, McKee, David D, Moore, John T, Watson, Michael A, Parks, Derek J, Lambert, Millard H, Willson, Timothy M

“…A cell-free assay was developed for the orphan nuclear receptor LXRα that measures the ligand-dependent recruitment of a peptide from the steroid receptor…”
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Biosynthesis of 24,25-epoxycholesterol from squalene 2,3;22,23-dioxide by Nelson, J A, Steckbeck, S R, Spencer, T A

“…[3H]Squalene 2,3(S);22(S),23-dioxide was prepared by incubation of [3H]mevalonate with S10 rat liver homogenate in the presence of 4,4,10…”
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Photoaffinity labeling of the oxysterol receptor by Taylor, F R, Kandutsch, A A, Anzalone, L, Phirwa, S, Spencer, T A

“…A cytosolic receptor protein for oxygenated sterols, postulated to be involved in the regulation of 3-hydroxy-3-methylglutaryl-CoA reductase and cholesterol…”
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