Search Results - "Spencer, Richard G S"

Exendin-4 Decelerates Food Intake, Weight Gain, and Fat Deposition in Zucker Rats by Szayna, Margarzata, Doyle, Máire E, Betkey, Jennifer A, Holloway, Harold W, Spencer, Richard G. S, Greig, Nigel H, Egan, Josephine M

“…Exendin-4 is a 39 amino acid peptide produced in the salivary gland of the Gila monster lizard. It has a 53% amino acid homology to the incretin hormone…”
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Microengineering neocartilage scaffolds by Petersen, Erik F., Spencer, Richard G. S., McFarland, Eric W.

“…Advances in micropatterning methodologies have made it possible to create structures with precise architecture on the surface of cell culture substrata. We…”
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Hyaline cartilage engineered by chondrocytes in pellet culture: histological, immunohistochemical and ultrastructural analysis in comparison with cartilage explants by Zhang, Zijun, McCaffery, J. Michael, Spencer, Richard G. S., Francomano, Clair A.

“…Cartilage engineering is a strategic experimental goal for the treatment of multiple joint diseases. Based on the process of embryonic chondrogenesis, we…”
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The effects of pulsed low-intensity ultrasound on chondrocyte viability, proliferation, gene expression and matrix production by Zhang, Zi-Jun, Huckle, James, Francomano, Clair A, Spencer, Richard G S

“…This study was designed to examine the effects of pulsed low-intensity ultrasound (PLIUS) on chondrocyte viability, proliferation, matrix production and gene…”
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The influence of pulsed low-intensity ultrasound on matrix production of chondrocytes at different stages of differentiation: an explant study by Zhang, Z i-Jun, Huckle, James, Francomano, Clair A, Spencer, Richard G S

“…The proximal and distal parts of sterna of chick embryos represent cartilage undergoing endochondral ossification and hyaline cartilage, respectively…”
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Growth and integration of neocartilage with native cartilage in vitro by Zhang, Zijun, McCaffery, J. Michael, Spencer, Richard G.S., Francomano, Clair A.

“…Poor integration of neocartilage with recipient has been a major obstacle to articular cartilage restoration. An in vitro study was designed to provide…”
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Imaging of collagen and proteoglycan in cartilage sections using Fourier transform infrared spectral imaging by Potter, Kimberlee, Kidder, Linda H., Levin, Ira W., Lewis, E. Neil, Spencer, Richard G. S.

“…Objective To test the hypothesis that Fourier transform infrared (FTIR) spectral imaging, coupled with multivariate data processing techniques, can image the…”
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In vivo biological activity of exendin (1-30) by Doyle, Máire E, McConville, Patrick, Theodorakis, Michael J, Goetschkes, Margaret M, Bernier, Michel, Spencer, Richard G S, Holloway, Harold W, Greig, Nigel H, Egan, Josephine M

“…Activation of the glucagon-like peptide-1 (GLP-1) receptor on pancreatic beta cells by GLP-1 and exendin-4 increases insulin secretion. Exendin-4 is 39 amino…”
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Bioreactor and probe system for magnetic resonance microimaging and spectroscopy of chondrocytes and neocartilage by Petersen, Erik, Potter, Kimberlee, Butler, John, Fishbein, Kenneth W., Horton, Walter, Spencer, Richard G. S., McFarland, Eric W.

“…We have developed a nuclear magnetic resonance (NMR)‐compatible hollow fiber chondrocyte bioreactor (HFBR), permitting the noninvasive study of neocartilage…”
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Matrix fixed‐charge density as determined by magnetic resonance microscopy of bioreactor‐derived hyaline cartilage correlates with biochemical and biomechanical properties by Chen, Chih‐Tung, Fishbein, Kenneth W., Torzilli, Peter A., Hilger, Amy, Spencer, Richard G. S., Horton, Walter E.

“…Objective To use noninvasive magnetic resonance imaging (MRI), biochemical analyses, and mechanical testing of engineered neocartilage grown in a hollow‐ fiber…”
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An unusual peptide conformation may precipitate amyloid formation in Alzheimer's disease: application of solid-state NMR to the determination of protein secondary structure by Spencer, Richard G. S, Halverson, Kurt J, Auger, Michele, McDermott, Ann E, Griffin, Robert G, Lansbury, Peter T

“…The formation of insoluble proteinaceous deposits is characteristic of many diseases which are collectively known as amyloidosis. There is very little…”
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Effect of long-term caloric restriction and exercise on muscle bioenergetics and force development in rats by Horska, A, Brant, L.J, Ingram, D.K, Hansford, R.G, Roth, G.S, Spencer, R.G.S

“…We evaluated the hypothesis that long-term caloric restriction and exercise would have beneficial effects on muscle bioenergetics and performance in the rat…”
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Time domain simulation of Fourier imaging by summation of isochromats by Shkarin, Pavel, Spencer, Richard G. S.

“…We have developed a time‐domain simulation of two‐dimensional Fourier imaging in which the signal is represented by a finite Fourier series. Each term…”
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Response of engineered cartilage tissue to biochemical agents as studied by proton magnetic resonance microscopy by Potter, Kimberlee, Butler, John J., Horton, Walter E., Spencer, Richard G. S.

“…Objective To test the hypothesis that magnetic resonance imaging (MRI) results correlate with the biochemical composition of cartilage matrix and can therefore…”
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Differences in the bioenergetic response of the isolated perfused rat heart to selective β1- and β2-Adrenergic receptor stimulation by MCCONVILLE, Patrick, FISHBEIN, Kenneth W, LAKATTA, Edward G, SPENCER, Richard G. S

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Guest editorial: Advanced signal processing in MRI. Part II by Spencer, Richard G. S.

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Ex vivo magnetic resonance microscopy of an osteochondral transfer by Petersen, Erik F., Fishbein, Kenneth W., Laouar, Leila, Spencer, Richard G.S., Wenz, James F.

“…A 49‐year‐old woman with right knee pain and a chondral defect on the medial femoral condyle underwent an osteochondral transfer. The patient initially had…”
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Histomorphometry of the Embryonic Avian Growth Plate by Proton Nuclear Magnetic Resonance Microscopy by Potter, Kimberlee, Landis, William J., Spencer, Richard G. S.

“…Quantitative nuclear magnetic resonance (NMR) microscopy was used to characterize the biochemical and morphological properties of the different zones within…”
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Differences in the bioenergetic response of the isolated perfused rat heart to selective beta1- and beta2-adrenergic receptor stimulation by McConville, Patrick, Fishbein, Kenneth W, Lakatta, Edward G, Spencer, Richard G S

“…In the heart, striking functional differences exist after stimulation of the beta1- and beta2-adrenergic receptor (AR) subtypes. These may be linked to…”
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The lever-coil: a simple, inexpensive sensor for respiratory and cardiac motion in MRI experiments by FISHBEIN, Kenneth W, MCCONVILLE, Patrick, SPENCER, Richard G. S

“…Thoracic and abdominal magnetic resonance imaging studies generally require some type of compensation for respiratory and cardiac motions in order to yield…”
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