Search Results - "Spencer, Haley F"
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Effects of Ketamine on Rodent Fear Memory
Published in International journal of molecular sciences (01-10-2020)“…Ketamine, a multimodal anesthetic drug, has become increasingly popular in the treatment of pain following traumatic injury as well as treatment-resistant…”
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Effects of Mild Closed-Head Injury and Subanesthetic Ketamine Infusion on Microglia, Axonal Injury, and Synaptic Density in Sprague-Dawley Rats
Published in International journal of molecular sciences (12-04-2024)“…Mild traumatic brain injury (mTBI) affects millions of people in the U.S. Approximately 20-30% of those individuals develop adverse symptoms lasting at least 3…”
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Effects of an intravenous ketamine infusion on inflammatory cytokine levels in male and female Sprague-Dawley rats
Published in Journal of neuroinflammation (04-04-2022)“…Ketamine, a multimodal dissociative anesthetic drug, is widely used as an analgesic following traumatic injury. Although ketamine may produce anti-inflammatory…”
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Enhanced Fear Memories and Altered Brain Glucose Metabolism ( 18 F-FDG-PET) following Subanesthetic Intravenous Ketamine Infusion in Female Sprague-Dawley Rats
Published in International journal of molecular sciences (08-02-2022)“…Although women and men are equally likely to receive ketamine following traumatic injury, little is known regarding sex-related differences in the impact of…”
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Ketamine, a trauma analgesic with sex-specific immunomodulatory function
Published in Neural regeneration research (01-06-2023)Get full text
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Punishment resistance for cocaine is associated with inflexible habits in rats
Published in Addiction neuroscience (01-06-2024)“…•Punishment resistance for cocaine is associated with continued use of habits.•Punishment sensitivity for cocaine is related to increased goal-directed…”
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Effects of a Subanesthetic Ketamine Infusion on Inflammatory and Behavioral Outcomes after Closed Head Injury in Rats
Published in Bioengineering (Basel) (01-08-2023)“…Traumatic brain injury (TBI) affects millions of people annually, and most cases are classified as mild TBI (mTBI). Ketamine is a potent trauma analgesic and…”
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Effects of subanesthetic intravenous ketamine infusion on neuroplasticity-related proteins in male and female Sprague-Dawley rats
Published in IBRO neuroscience reports (01-12-2021)“…Although ketamine, a multimodal dissociative anesthetic, is frequently used for analgesia and treatment-resistant major depression, molecular mechanisms of…”
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Random interval schedule of reinforcement influences punishment resistance for cocaine in rats
Published in Neurobiology of learning and memory (01-09-2024)“…•Punishment resistance for cocaine is greater with RI60 schedule as compared to RR20.•Punishment resistance for food is greater with RI60 than RR20 in females,…”
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Prelimbic cortical projections to rostromedial tegmental nucleus play a suppressive role in cue-induced reinstatement of cocaine seeking
Published in Neuropsychopharmacology (New York, N.Y.) (01-07-2021)“…The prelimbic (PL) region of prefrontal cortex has been implicated in both driving and suppressing cocaine seeking in animal models of addiction. We…”
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Discriminating goal-directed and habitual cocaine seeking in rats using a novel outcome devaluation procedure
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-12-2022)“…Habits are theorized to play a key role in compulsive cocaine seeking, yet there is limited methodology for assessing habitual responding for intravenous (IV)…”
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Association between intravenous ketamine-induced stress hormone levels and long-term fear memory renewal in Sprague-Dawley rats
Published in Behavioural brain research (27-01-2020)“…•An IV ketamine infusion (10 mg/kg) produces sedation, antinociception, and elevation of corticosterone and progesterone levels in rats.•Post-fear conditioning…”
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Discriminating goal-directed and habitual cocaine seeking in rats using a novel outcome devaluation procedure
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-12-2022)“…Habits are theorized to play a key role in compulsive cocaine seeking, yet there is limited methodology for assessing habitual responding for intravenous (IV)…”
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