Search Results - "Spencer, Diane M."

The Binding of Monoclonal and Polyclonal Anti-Z-DNA Antibodies to DNA of Various Species Origin by Spencer, Diane M., Reyna, Angel Garza, Pisetsky, David S.

“…DNA is a polymeric macromolecule that can display a variety of backbone conformations. While the classical B-DNA is a right-handed double helix, Z-DNA is a…”
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The Binding Properties of Antibodies to Z-DNA in the Sera of Normal Healthy Subjects by Pisetsky, David S, Gedye, Matthew J, David, Lawrence A, Spencer, Diane M

“…Antibodies to DNA are a diverse set of antibodies that bind sites on DNA, a polymeric macromolecule that displays various conformations. In a previous study,…”
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The Interaction of Anti-DNA Antibodies with DNA: Evidence for Unconventional Binding Mechanisms by Pisetsky, David S, Garza Reyna, Angel, Belina, Morgan E, Spencer, Diane M

“…Antibodies to DNA (anti-DNA) are the serological hallmark of systemic lupus erythematosus, a prototypic autoimmune disease. These antibodies bind to conserved…”
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Effects of Progesterone and Estradiol Sex Hormones on the Release of Microparticles by RAW 264.7 Macrophages Stimulated by Poly(I:C) by Pisetsky, David S, Spencer, Diane M

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Mixed-surface polyamidoamine polymer variants retain nucleic acid-scavenger ability with reduced toxicity by Olson, Lyra B., Hunter, Nicole I., Rempel, Rachel E., Yu, Haixiang, Spencer, Diane M., Sullenger, Cynthia Z., Greene, William S., Varanko, Anastasia K., Eghtesadi, Seyed A., Chilkoti, Ashutosh, Pisetsky, David S., Everitt, Jeffrey I., Sullenger, Bruce A.

“…Nucleic acid-binding polymers can have anti-inflammatory properties and beneficial effects in animal models of infection, trauma, cancer, and autoimmunity…”
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Assay variation in the detection of antinuclear antibodies in the sera of patients with established SLE by Pisetsky, David S, Spencer, Diane M, Lipsky, Peter E, Rovin, Brad H

“…The expression of antinuclear antibodies (ANA) is considered almost constant in systemic lupus erythematosus (SLE), although recent experience has suggested…”
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Role of Phosphorylation Sites and the C2 Domain in Regulation of Cytosolic Phospholipase A2 by Gijón, Miguel A., Spencer, Diane M., Kaiser, Alan L., Leslie, Christina C.

“…Cytosolic phospholipase A2 (cPLA2) mediates agonist-induced arachidonic acid release, the first step in eicosanoid production. cPLA2 is regulated by…”
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The interaction of anti-DNA antibodies with DNA antigen: Evidence for hysteresis for high avidity binding by Pisetsky, David S., Shaffer, Robert, Armstrong, Dustin D., Spencer, Diane M.

“…Antibodies to DNA (anti-DNA) are the serological hallmark of systemic lupus erythematosus. Previous studies have indicated that the phosphodiester backbone is…”
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The expression of antibodies to Z-DNA in the blood of patients with systemic lupus erythematosus: Relationship to autoantibodies to B-DNA by Spencer, Diane M., Svenungsson, Elisabet, Gunnarsson, Iva, Caricchio, Roberto, Pisetsky, David S.

“…To explore the antibody response to Z-DNA, a DNA conformation with a zig-zag structure, blood of patients with systemic lupus erythematosus (SLE) and otherwise…”
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Response to: "Antinuclear autoantibodies: discordance among four different assays" by Pacheco et al by Pisetsky, David S, Spencer, Diane M, Lipsky, Peter E, Rovin, Brad

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The binding of SLE autoantibodies to mitochondria by Pisetsky, David S., Spencer, Diane M., Mobarrez, Fariborz, Fuzzi, Enrico, Gunnarsson, Iva, Svenungsson, Elisabet

“…Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterized by immune complexes. Because these complexes contain mitochondrial…”
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Response to: 'Can solid-phase assays replace immunofluorescence for ANA screening?' by Bizzaro by Pisetsky, David S, Spencer, Diane M, Lipsky, Peter E, Rovin, Brad H

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Response to: 'ANA testing in "real life"' by Infantino et al by Pisetsky, David S, Spencer, Diane M, Lipsky, Peter E, Rovin, Brad H

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Response to: 'Antinuclear antibody as entry criterion for classification of systemic lupus erythematosus: pitfalls and opportunities' by Bossuyt et al by Pisetsky, David S, Spencer, Diane M, Lipsky, Peter E, Rovin, Brad H

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Regulation of cytosolic phospholipase A2α by hsp90 and a p54 kinase in okadaic acid-stimulated macrophages by Tucker, Dawn E., Gijón, Miguel A., Spencer, Diane M., Qiu, Zhi‐Hua, Gelb, Michael H., Leslie, Christina C.

“…In resident mouse peritoneal macrophages, group IVA cytosolic phospholipase A2 (cPLA2α) mediates arachidonic acid (AA) release and eicosanoid production in…”
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Response to: 'Lack of standardization of ANA and implications for drug development and precision medicine' by Mahler by Pisetsky, David S, Spencer, Diane M, Lipsky, Peter E, Rovin, Brad H

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Response to: 'Variation in antinuclear antibody detection by automated indirect immunofluorescence analysis' by van Hoovels et al by Pisetsky, David S, Spencer, Diane M, Lipsky, Peter E, Rovin, Brad H

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Response to: 'Unending story of the indirect immunofluorescence assay on HEp-2 cells: old problems and new solutions?' by Meroni et al by Pisetsky, David S, Spencer, Diane M, Lipsky, Peter E, Rovin, Brad H

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Response to: 'Pitfalls of antinuclear antibody detection in systemic lupus erythematosus: the positive experience of a national multi-center study' by Pregnalato et al by Pisetsky, David S, Spencer, Diane M, Lipsky, Peter E, Rovin, Brad H

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The release of microparticles and mitochondria from RAW 264.7 murine macrophage cells undergoing necroptotic cell death in vitro by Spencer, Diane M., Dye, John R., Piantadosi, Claude A., Pisetsky, David S.

“…Microparticles (MPs) are small membrane-bound vesicles released from activated or dying cells. As shown previously, LPS stimulation of the RAW 264.7 macrophage…”
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