Search Results - "Spencer, Alison K"
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Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer
Published in Genes & development (15-01-2016)“…Proteases are important for regulating multiple tumorigenic processes, including angiogenesis, tumor growth, and invasion. Elevated protease expression is…”
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A new approach to identifying patients with elevated risk for Fabry disease using a machine learning algorithm
Published in Orphanet journal of rare diseases (20-12-2021)“…Fabry disease (FD) is a rare genetic disorder characterized by glycosphingolipid accumulation and progressive damage across multiple organ systems. Due to its…”
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Validation of a machine learning approach to estimate Clinical Disease Activity Index Scores for rheumatoid arthritis
Published in Rheumatic & musculoskeletal diseases open (01-11-2021)“…ObjectiveDisease activity measures, such as the Clinical Disease Activity Index (CDAI), are important tools for informing treatment decisions and monitoring…”
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Scaling of cytoskeletal organization with cell size in Drosophila
Published in Molecular biology of the cell (01-06-2017)“…Spatially organized macromolecular complexes are essential for cell and tissue function, but the mechanisms that organize micron-scale structures within cells…”
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Utilization of artificial intelligence to identify undiagnosed Fabry patients: Development of a validated machine learning model
Published in Molecular genetics and metabolism (01-02-2021)Get full text
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