Search Results - "Spence, David J"
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Patent Foramen Ovale Closure or Antiplatelet Therapy for Cryptogenic Stroke
Published in The New England journal of medicine (14-09-2017)“…In a randomized trial involving 664 patients who had had a cryptogenic stroke, closure of a PFO combined with antiplatelet therapy resulted in significantly…”
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Risk from low blood pressure in frail older adults: diastolic pressure and pulse pressure are important
Published in Age and ageing (01-11-2021)“…Abstract Blood pressure measurement with a cuff in patients with stiff arteries can be misleading, with false elevation of the diastolic pressure. Coronary…”
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Nutrition and Risk of Stroke
Published in Nutrients (17-03-2019)“…Nutrition is far more important in stroke risk than most physcians suppose. Healthy lifestyle choices reduce the risk of stroke by ~80%, and of the factors…”
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Socioeconomic status and stroke incidence, prevalence, mortality, and worldwide burden: an ecological analysis from the Global Burden of Disease Study 2017
Published in BMC medicine (24-10-2019)“…Socioeconomic status (SES) is associated with stroke incidence and mortality. Distribution of stroke risk factors is changing worldwide; evidence on these…”
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Mechanisms of Stroke in COVID-19
Published in Cerebrovascular diseases (Basel, Switzerland) (01-09-2020)Get more information
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Resistant Atherosclerosis: The Need for Monitoring of Plaque Burden
Published in Stroke (1970) (01-06-2017)“…Recent studies indicate that patients with lower levels of low-density lipoprotein cholesterol (LDL-C) have greater regression of coronary plaque. In 2002, we…”
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Commentary: Effect of aspirin in patients with established asymptomatic carotid atherosclerosis: a systematic review and meta-analysis
Published in Frontiers in pharmacology (29-06-2023)Get full text
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Importance of sex and gender in atherosclerosis and cardiovascular disease
Published in Atherosclerosis (01-07-2015)Get full text
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Hypertension in blacks: insights from Africa
Published in Journal of hypertension (01-02-2017)“…Although the consequences of hypertension are universal, blacks (African-Americans or indigenous Africans) have been the subject of a differential approach to…”
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Atrial Fibrillation in Patients with Cryptogenic Stroke
Published in The New England journal of medicine (26-06-2014)“…In this study, patients with cryptogenic stroke who were randomly assigned to undergo intensive ECG monitoring for 30 days had a higher incidence of detected…”
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Pioglitazone after Ischemic Stroke or Transient Ischemic Attack
Published in The New England journal of medicine (07-04-2016)“…In this trial in nondiabetic patients with insulin resistance and a recent ischemic stroke or transient ischemic attack, pioglitazone was associated with a…”
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Beyond hypertension: hypertension with hyperhomocysteinemia
Published in Science bulletin (Beijing) (30-09-2023)Get full text
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Endarterectomy, Stenting, or Neither for Asymptomatic Carotid-Artery Stenosis
Published in The New England journal of medicine (17-03-2016)“…Important data from two large, randomized trials comparing early and late outcomes after carotid endarterectomy and carotid-artery stenting have now been…”
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Diet for stroke prevention
Published in Stroke and vascular neurology (01-06-2018)“…Lifestyle is far more important than most physicians suppose. Dietary changes in China that have resulted from increased prosperity are probably responsible…”
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Sex differences in the intestinal microbiome: interactions with risk factors for atherosclerosis and cardiovascular disease
Published in Biology of sex differences (17-05-2021)“…There are clearly sex differences in cardiovascular disease. On average, women experience cardiovascular events at an older age, and at any age, women, on…”
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Mechanisms of Lipoprotein(a) Pathogenicity: Prothrombotic, Proatherosclerotic, or Both?
Published in Arteriosclerosis, thrombosis, and vascular biology (01-07-2012)Get full text
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Secular Trends in Ischemic Stroke Subtypes and Stroke Risk Factors
Published in Stroke (1970) (01-11-2014)“…Early diagnosis and treatment of a stroke improves patient outcomes, and knowledge of the cause of the initial event is crucial to identification of the…”
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Triglyceride/High‐Density Lipoprotein Cholesterol Ratio: A Clue to Metabolic Syndrome, Insulin Resistance, and Severe Atherosclerosis
Published in Lipids (01-07-2021)“…High serum levels of triglycerides (Tg) and low levels of high‐density lipoprotein cholesterol (HDL‐C) are characteristic of the Metabolic Syndrome (MetS). We…”
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Effect of renal impairment on atherosclerosis: only partially mediated by homocysteine
Published in Nephrology, dialysis, transplantation (01-06-2016)“…Cardiovascular risk and plasma total homocysteine (tHcy) are high in patients with renal failure. High tHcy may account for a substantial part of the increased…”
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