Search Results - "Spelta, Valeria"

Subunit Arrangement in P2X Receptors by Jiang, Lin-Hua, Kim, Miran, Spelta, Valeria, Bo, Xuenong, Surprenant, Annmarie, North, R. Alan

“…ATP-gated ionotropic receptors (P2X receptors) are distributed widely in the nervous system. For example, a hetero-oligomeric receptor containing both P2X2 and…”
Get full text

Differential Assembly of Rat Purinergic P2X7 Receptor in Immune Cells of the Brain and Periphery by Kim, Miran, Spelta, Valeria, Sim, Joan, North, R. Alan, Surprenant, Annmarie

“…ATP-gated P2X7 purinoceptors are found in most immune cells of the periphery and the brain where their activation leads to multiple downstream events such as…”
Get full text

Amino Acid Residues Involved in Gating Identified in the First Membrane-spanning Domain of the Rat P2X2 Receptor by Jiang, Lin-Hua, Rassendren, François, Spelta, Valeria, Surprenant, Annmarie, North, R. Alan

“…The first hydrophobic segment of the rat P2X2 receptor extends from residue Leu29to Val51. In the rat P2X2 receptor, we mutated amino acids in this segment and…”
Get full text

Investment, insurance and weather shocks: Evidence from Cambodia by Falco, Chiara, Rotondi, Valentina, Kong, Douch, Spelta, Valeria

“…The livelihoods of poor people in developing countries are increasingly dependent on weather shocks whose effects are exacerbated by the lack of access to…”
Get full text

Sensing Muscle Ischemia: Coincident Detection of Acid and ATP via Interplay of Two Ion Channels by Birdsong, William T., Fierro, Leonardo, Williams, Frank G., Spelta, Valeria, Naves, Ligia A., Knowles, Michelle, Marsh-Haffner, Josephine, Adelman, John P., Almers, Wolfhard, Elde, Robert P., McCleskey, Edwin W.

“…Ischemic pain—examples include the chest pain of a heart attack and the leg pain of a 30 s sprint—occurs when muscle gets too little oxygen for its metabolic…”
Get full text

Prejunctional muscarinic inhibitory control of acetylcholine release in the human isolated detrusor: involvement of the M 4 receptor subtype by D'Agostino, Gianluigi, Bolognesi, Maria L, Lucchelli, Adele, Vicini, Davide, Balestra, Barbara, Spelta, Valeria, Melchiorre, Carlo, Tonini, Marcello

“…Experiments were carried out in human detrusor strips to characterize muscarinic receptor subtypes involved in the prejunctional regulation of acetylcholine…”
Get full text

ATP analogues with modified phosphate chains and their selectivity for rat P2X 2 and P2X 2/3 receptors by Spelta, Valeria, Mekhalfia, Abdelaziz, Rejman, Dominik, Thompson, Mark, Blackburn, G Michael, North, R Alan

“…Heteromeric P2X 2/3 receptors are much more sensitive than homomeric P2X 2 receptors to αβ ‐methylene‐ATP, and this ATP analogue is widely used to discriminate…”
Get full text

Kinetics of antagonist actions at rat P2X 2/3 heteromeric receptors by Spelta, Valeria, Jiang, Lin‐Hua, Surprenant, Annmarie, North, R Alan

“…Currents through heteromeric P2X 2/3 receptors were evoked by applying α,β‐methylene‐ATP to human embryonic kidney cells transfected with cDNAs encoding the…”
Get full text

Interaction between cysteines introduced into each transmembrane domain of the rat P2X 2 receptor by Spelta, Valeria, Jiang, Lin‐Hua, Bailey, R Jayne, Surprenant, Annmarie, North, R Alan

“…ATP‐gated ion channels (P2X receptors) contain two hydrophobic segments that are presumed to span the plasma membrane (TM1 and TM2). Pairs of cysteines were…”
Get full text

Kinetics of antagonist actions at rat P2X2/3 heteromeric receptors by Spelta, Valeria, Jiang, Lin‐Hua, Surprenant, Annmarie, North, R Alan

“…Currents through heteromeric P2X2/3 receptors were evoked by applying α,β‐methylene‐ATP to human embryonic kidney cells transfected with cDNAs encoding the…”
Get full text

Prejunctional muscarinic inhibitory control of acetylcholine release in the human isolated detrusor: involvement of the M4 receptor subtype by D'Agostino, Gianluigi, Bolognesi, Maria L, Lucchelli, Adele, Vicini, Davide, Balestra, Barbara, Spelta, Valeria, Melchiorre, Carlo, Tonini, Marcello

“…Experiments were carried out in human detrusor strips to characterize muscarinic receptor subtypes involved in the prejunctional regulation of acetylcholine…”
Get full text

Tachykinin-dependent and -independent components of peristalsis in the guinea pig isolated distal colon by Tonini, Marcello, Spelta, Valeria, de Ponti, Fabrizio, de Giorgio, Roberto, D'Agostino, Gianluigi, Stanghellini, Vincenzo, Corinaldesi, Roberto, Sternini, Catia, Crema, Francesca

“…Background & Aims: In the intestine, tachykinins regulate motility by participating in neuromuscular and neuro-neuronal transmission. The aim of this study was…”
Get full text

Interaction between cysteines introduced into each transmembrane domain of the rat P2X2 receptor by Spelta, Valeria, Jiang, Lin‐Hua, Bailey, R Jayne, Surprenant, Annmarie, North, R Alan

“…ATP‐gated ion channels (P2X receptors) contain two hydrophobic segments that are presumed to span the plasma membrane (TM1 and TM2). Pairs of cysteines were…”
Get full text

ATP analogues with modified phosphate chains and their selectivity for rat P2X2 and P2X2/3 receptors by Spelta, Valeria, Mekhalfia, Abdelaziz, Rejman, Dominik, Thompson, Mark, Blackburn, G Michael, North, R Alan

“…Heteromeric P2X2/3 receptors are much more sensitive than homomeric P2X2 receptors to αβ‐methylene‐ATP, and this ATP analogue is widely used to discriminate…”
Get full text

Role of galanin receptor 1 in the galanin-induced inhibition of intestinal motility by Sternini, Catia, Balestra, Barbara, Pham, Thomas, Spelta, Valeria, D'Agostino, Gianluigi, Reeve, Joseph R., Won, Helen, Walsh, John H., Tonini, Marcello

Get full text

2‐Phenylmelatonin: A Partial Agonist at Enteric Melatonin Receptors by Santagostino‐Barbone, Maria Grazia, Masoero, Elisabetta, Spelta, Valeria, Lucchelli, Adele

“…: The effect of the melatonin receptor ligand, 2‐phenylmelatonin, has been assessed in isolated strips of the guinea‐pig proximal colon. 2‐Phenylmelatonin…”
Get full text

2-phenylmelatonin : A partial agonist at enteric melatonin receptors by SANTAGOSTINO-BARBONE, Maria Grazia, MASOERO, Elisabetta, SPELTA, Valeria, LUCCHELLI, Adele

“…The effect of the melatonin receptor ligand, 2-phenylmelatonin, has been assessed in isolated strips of the guinea-pig proximal colon. 2-Phenylmelatonin (0.01…”
Get full text

Fluoroquinolone‐Induced Motor Changes in the Guinea‐Pig Isolated Ileum by Nucci, Amalia Di, Candura, Stefano M., Tagliani, Monica, D'Agostino, Gianluigi, Spelta, Valeria, Fiori, Enrico, Ricotti, Paola, Tonini, Marcello

“…: The effects of norfloxacin and enoxacin were examined on spontaneous motor activity in the guinea‐pig isolated ileum. Micromolar concentrations of both…”
Get full text