Search Results - "Speidel, Alessondra T"
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Multimodal Hydrogel-Based Platform To Deliver and Monitor Cardiac Progenitor/Stem Cell Engraftment
Published in ACS central science (26-04-2017)“…Retention and survival of transplanted cells are major limitations to the efficacy of regenerative medicine, with short-term paracrine signals being the…”
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Four Food and Drug Administration draft guidance documents and the REGROW Act: A litmus test for future changes in human cell‐ and tissue‐based products regulatory policy in the United States?
Published in Journal of tissue engineering and regenerative medicine (01-07-2018)“…Modern regenerative medicine research has expanded well past the development of traditional drugs and medical devices with many promising new therapies…”
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Ascendancy of semi-synthetic biomaterials from design towards democratization
Published in Nature materials (01-09-2022)“…Semi-synthetic goldilocks material design integrates the tunable characteristics of synthetic materials and the refined complexity of natural components,…”
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High-throughput screening of microscale pitted substrate topographies for enhanced nonviral transfection efficiency in primary human fibroblasts
Published in Biomaterials (01-05-2011)“…Abstract Optimization of nonviral gene delivery typically focuses on the design of particulate carriers that are endowed with desirable membrane targeting,…”
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Tailored Biocompatible Polyurethane‐Poly(ethylene glycol) Hydrogels as a Versatile Nonfouling Biomaterial
Published in Advanced healthcare materials (01-11-2022)“…Polyurethane‐based hydrogels are relatively inexpensive and mechanically robust biomaterials with ideal properties for various applications, including drug…”
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Cellular shape reinforces niche to stem cell signaling in the small intestine
Published in Science advances (14-10-2022)“…Niche-derived factors regulate tissue stem cells, but apart from the mechanosensory pathways, the effect of niche geometry is not well understood. We used…”
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