Search Results - "Speer, Allison L."

Human and mouse tissue-engineered small intestine both demonstrate digestive and absorptive function by Grant, Christa N, Mojica, Salvador Garcia, Sala, Frederic G, Hill, J Ryan, Levin, Daniel E, Speer, Allison L, Barthel, Erik R, Shimada, Hiroyuki, Zachos, Nicholas C, Grikscheit, Tracy C

“…Short bowel syndrome (SBS) is a devastating condition in which insufficient small intestinal surface area results in malnutrition and dependence on intravenous…”
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Infant and adult human intestinal enteroids are morphologically and functionally distinct by Adeniyi-Ipadeola, Grace O, Hankins, Julia D, Kambal, Amal, Zeng, Xi-Lei, Patil, Ketki, Poplaski, Victoria, Bomidi, Carolyn, Nguyen-Phuc, Hoa, Grimm, Sandra L, Coarfa, Cristian, Stossi, Fabio, Crawford, Sue E, Blutt, Sarah E, Speer, Allison L, Estes, Mary K, Ramani, Sasirekha

“…Human intestinal enteroids (HIEs) are gaining recognition as physiologically relevant models of the intestinal epithelium. While HIEs from adults are used…”
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The impact of acute coagulopathy on mortality in pediatric trauma patients by Strumwasser, Aaron, Speer, Allison L, Inaba, Kenji, Branco, Bernardino C, Upperman, Jeffrey S, Ford, Henri R, Lam, Lydia, Talving, Peep, Shulman, Ira, Demetriades, Demetrios

“…Traumatic coagulopathy (TC) occurs in 24% to 38% of adults and is associated with up to a six-fold increase in mortality. This study's purpose was to determine…”
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A multicellular approach forms a significant amount of tissue-engineered small intestine in the mouse by Sala, Frédéric G, Matthews, Jamil A, Speer, Allison L, Torashima, Yasuhiro, Barthel, Erik R, Grikscheit, Tracy C

“…Tissue-engineered small intestine (TESI) has successfully been used to rescue Lewis rats after massive small bowel resection. In this study, we transitioned…”
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Murine Tissue-Engineered Stomach Demonstrates Epithelial Differentiation by Speer, Allison L., M.D, Sala, Frederic G., Ph.D, Matthews, Jamil A., M.D, Grikscheit, Tracy C., M.D

“…Background Gastric cancer remains the second largest cause of cancer-related mortality worldwide. Postgastrectomy morbidity is considerable and quality of life…”
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Insights into human norovirus cultivation in human intestinal enteroids by Ettayebi, Khalil, Kaur, Gurpreet, Patil, Ketki, Dave, Janam, Ayyar, B Vijayalakshmi, Tenge, Victoria R, Neill, Frederick H, Zeng, Xi-Lei, Speer, Allison L, Di Rienzi, Sara C, Britton, Robert A, Blutt, Sarah E, Crawford, Sue E, Ramani, Sasirekha, Atmar, Robert L, Estes, Mary K

“…Human noroviruses (HuNoVs) are a significant cause of epidemic and sporadic acute gastroenteritis worldwide. The lack of a reproducible culture system hindered…”
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Vitrification preserves murine and human donor cells for generation of tissue-engineered intestine by Spurrier, Ryan G., MD, Speer, Allison L., MD, Grant, Christa N., MD, Levin, Daniel E., MD, Grikscheit, Tracy C., MD

“…Abstract Background Short bowel syndrome causes significant morbidity and mortality. Tissue-engineered intestine may serve as a viable replacement…”
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Regenerative medicine technologies applied to transplant medicine. An update by Petrosyan, Astgik, Montali, Filippo, Peloso, Andrea, Citro, Antonio, Byers, Lori N, La Pointe, Catherine, Suleiman, Mara, Marchetti, Alice, Mcneill, Eoin P, Speer, Allison L, Ng, Wai Hoe, Ren, Xi, Bussolati, Benedetta, Perin, Laura, Di Nardo, Paolo, Cardinale, Vincenzo, Duisit, Jerome, Monetti, Alexandra Rose, Savino, John Richard, Asthana, Amish, Orlando, Giuseppe

“…Regenerative medicine (RM) is changing how we think and practice transplant medicine. In regenerative medicine, the aim is to develop and employ methods to…”
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Bioengineering of Intestinal Grafts by Herath, Madushani, Speer, Allison L.

“…Intestinal failure manifests as an impaired capacity of the intestine to sufficiently absorb vital nutrients and electrolytes essential for growth and…”
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A "living bioreactor" for the production of tissue-engineered small intestine by Levin, Daniel E, Sala, Frederic G, Barthel, Erik R, Speer, Allison L, Hou, Xiaogang, Torashima, Yasuhiro, Grikscheit, Tracy C

“…Here, we describe the use of a mouse model as a living bioreactor for the generation of tissue-engineered small intestine. Small intestine is harvested from…”
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Fibroblast growth factor 10-fibroblast growth factor receptor 2b mediated signaling is not required for adult glandular stomach homeostasis by Speer, Allison L, Al Alam, Denise, Sala, Frederic G, Ford, Henri R, Bellusci, Saverio, Grikscheit, Tracy C

“…The signaling pathways that are essential for gastric organogenesis have been studied in some detail; however, those that regulate the maintenance of the…”
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Invited Commentary for Disruption of Enterohepatic Circulation of Bile Acids Ameliorates Small Bowel Resection Associated Hepatic Injury by Speer, Allison L., Fauza, Dario O.

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Severe acquired tracheomalacia caused by a chronic esophageal foreign body by Mulcahy, Collin F, Park, Joseph C, Rubio, Eva I, Speer, Allison L, Badillo, Andrea, Pena, Maria

“…AbstractA 3-year-old otherwise healthy boy presented with new-onset progressive stridor that began 3 months prior. He was noted to have dyspnea on exertion,…”
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Sodium Bicarbonate Locks May Be a Safe and Effective Alternative in Pediatric Intestinal Failure: A Pilot Study by Josyabhatla, Rohit, Naik, Mamta, Liu, Yuying, Speer, Allison L., Imseis, Essam M.

“…This was a retrospective study that compared outcomes in pediatric intestinal failure (IF) patients that were switched from ethanol lock therapy (ELT) to…”
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Comparison of two formulations of intravenous lipid emulsions in pediatric intestinal failure by Naik, Mamta, Lawrence, Alexandria, Davidson, Allison, Chapman, John, Ferguson, Dalya, Speer, Allison L., Imseis, Essam

“…Purpose The effect of different types of lipid emulsion may guide therapy of patients with intestinal failure (IF) to limit morbidity such as intestinal…”
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Mesenchymal-Specific Inhibition of Vascular Endothelial Growth Factor (VEGF) Attenuates Growth in Neonatal Mice by Matthews, Jamil A., M.D, Sala, Frédéric G., Ph.D, Speer, Allison L., M.D, Li, Ying, M.D., Ph.D, Warburton, David, M.D, Grikscheit, Tracy C., M.D

“…Background Vascular endothelial growth factor (VEGF) is a key mediator of angiogenesis and vasculogenesis. However, the role of VEGF in the regulation of…”
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Are We Enhancing Recovery After Neonatal Surgery? Assessment of Enhanced Recovery After Surgery Principles for Ostomy Takedown by Werth, Shaige L., Hebballi, Nutan B., Bordelon, Rachel C., Reynolds, Eric W., Tsao, Kuojen, Speer, Allison L.

“…Enhanced Recovery After Surgery (ERAS) guidelines in adults have demonstrated reduced complications, length of stay, and cost. However, neonatal ERAS studies…”
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Delayed family reunification of pediatric disaster survivors increases mortality and inpatient hospital costs: a simulation study by Barthel, Erik R., MD, PhD, Pierce, James R., MD, Speer, Allison L., MD, Levin, Daniel E., MD, Goodhue, Catherine J., RN, Ford, Henri R., MD, MHA, Grikscheit, Tracy C., MD, Upperman, Jeffrey S., MD

“…Abstract Background Disasters occur randomly and can severely tax the health care delivery system of affected and surrounding regions. A significant proportion…”
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Investigation of murine host sex as a biological variable in epithelial barrier function and muscle contractility in human intestinal organoids by Beanland, Brooke T., McNeill, Eoin P., Sequeira, David J., Xue, Hasen, Shroyer, Noah F., Speer, Allison L.

“…Intestinal failure (IF) occurs when intestinal surface area or function is not sufficient to support digestion and nutrient absorption. Human intestinal…”
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Evaluation of Murine Host Sex as a Biological Variable in Transplanted Human Intestinal Organoid Development by McNeill, Eoin P., Gupta, Vikas S., Sequeira, David J., Shroyer, Noah F., Speer, Allison L.

“…Background Human intestinal organoids (HIOs), when transplanted into immunocompromised mice (tHIOs), demonstrate significant growth and maturation. While both…”
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