Search Results - "Speed, T"

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias by BOLSTAD, B. M, IRIZARRY, R. A, ASTRAND, M, SPEED, T. P

“…When running experiments that involve multiple high density oligonucleotide arrays, it is important to remove sources of variation between arrays of…”
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Estimation and assessment of raw copy numbers at the single locus level by Bengtsson, H., Irizarry, R., Carvalho, B., Speed, T. P.

“…Motivation: Although copy-number aberrations are known to contribute to the diversity of the human DNA and cause various diseases, many aberrations and their…”
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Genomic characterisation of hormone receptor-positive breast cancer arising in very young women by Luen, S.J., Viale, G., Nik-Zainal, S., Savas, P., Kammler, R., Dell’Orto, P., Biasi, O., Degasperi, A., Brown, L.C., Láng, I., MacGrogan, G., Tondini, C., Bellet, M., Villa, F., Bernardo, A., Ciruelos, E., Karlsson, P., Neven, P., Climent, M., Müller, B., Jochum, W., Bonnefoi, H., Martino, S., Davidson, N.E., Geyer, C., Chia, S.K., Ingle, J.N., Coleman, R., Solbach, C., Thürlimann, B., Colleoni, M., Coates, A.S., Goldhirsch, A., Fleming, G.F., Francis, P.A., Speed, T.P., Regan, M.M., Loi, S.

“…Very young premenopausal women diagnosed with hormone receptor-positive, human epidermal growth factor receptor 2-negative (HR+HER2−) early breast cancer (EBC)…”
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FIRMA: a method for detection of alternative splicing from exon array data by Purdom, E., Simpson, K. M., Robinson, M. D., Conboy, J. G., Lapuk, A. V., Speed, T.P.

“…Motivation: Analyses of EST data show that alternative splicing is much more widespread than once thought. The advent of exon and tiling microarrays means that…”
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Mitochondrial-related gene expression changes are sensitive to agonal-pH state: implications for brain disorders by VAWTER, M. P, TOMITA, H, WALSH, D. M, BURMEISTER, M, SPEED, T, MYERS, R, JONES, E. G, WATSON, S. J, AKIL, H, BUNNEY, W. E, MENG, F, BOLSTAD, B, LI, J, EVANS, S, CHOUDARY, P, ATZ, M, SHAO, L, NEAL, C

“…Mitochondrial defects in gene expression have been implicated in the pathophysiology of bipolar disorder and schizophrenia. We have now contrasted control…”
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Sex differences in measures of central sensitization and pain sensitivity to experimental sleep disruption: implications for sex differences in chronic pain by Smith, Jr, Michael T, Remeniuk, Bethany, Finan, Patrick H, Speed, Traci J, Tompkins, D Andrew, Robinson, Mercedes, Gonzalez, Kaylin, Bjurstrom, Martin F, Irwin, Michael R

“…Females demonstrate heightened central sensitization (CS), a risk factor for chronic pain characterized by enhanced responsivity of central nervous system…”
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Replication of KIAA0350, IL2RA, RPL5 and CD58 as multiple sclerosis susceptibility genes in Australians by Rubio, J P, Stankovich, J, Field, J, Tubridy, N, Marriott, M, Chapman, C, Bahlo, M, Perera, D, Johnson, L J, Tait, B D, Varney, M D, Speed, T P, Taylor, B V, Foote, S J, Butzkueven, H, Kilpatrick, T J

“…A recent genome-wide association study (GWAS) conducted by the International Multiple Sclerosis Genetics Consortium (IMSGC) identified a number of putative MS…”
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Summaries of Affymetrix GeneChip probe level data by Irizarry, Rafael A., Bolstad, Benjamin M., Collin, Francois, Cope, Leslie M., Hobbs, Bridget, Speed, Terence P.

“…High density oligonucleotide array technology is widely used in many areas of biomedical research for quantitative and highly parallel measurements of gene…”
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Comparison of Discrimination Methods for the Classification of Tumors Using Gene Expression Data by Dudoit, Sandrine, Fridlyand, Jane, Speed, Terence P

“…A reliable and precise classification of tumors is essential for successful diagnosis and treatment of cancer. cDNA microarrays and high-density…”
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Distribution of genomic breakpoints in chronic myeloid leukemia: analysis of 308 patients by Ross, D M, O'Hely, M, Bartley, P A, Dang, P, Score, J, Goyne, J M, Sobrinho-Simoes, M, Cross, N C P, Melo, J V, Speed, T P, Hughes, T P, Morley, A A

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Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation by Yang, Yee Hwa, Dudoit, Sandrine, Luu, Percy, Lin, David M, Peng, Vivian, Ngai, John, Speed, Terence P

“…There are many sources of systematic variation in cDNA microarray experiments which affect the measured gene expression levels (e.g. differences in labeling…”
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Using control genes to correct for unwanted variation in microarray data by Gagnon-Bartsch, J. A., Speed, T. P.

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Alveolar lining layer is thin and continuous: low-temperature scanning electron microscopy of rat lung by Bastacky, J, Lee, C Y, Goerke, J, Koushafar, H, Yager, D, Kenaga, L, Speed, T P, Chen, Y, Clements, J A

“…The low-temperature electron microscope, which preserves aqueous structures as solid water at liquid nitrogen temperature, was used to image the alveolar…”
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Analysis of cDNA microarray images by Yang, Y H, Buckley, M J, Speed, T P

“…Microarrays are part of a new class of biotechnologies that allow the monitoring of expression levels for thousands of genes simultaneously. Image analysis is…”
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Experimental design and low-level analysis of microarray data by Bolstad, B M, Collin, F, Simpson, K M, Irizarry, R A, Speed, T P

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Exploration, normalization, and genotype calls of high-density oligonucleotide SNP array data by Carvalho, Benilton, Bengtsson, Henrik, Speed, Terence P, Irizarry, Rafael A

“…In most microarray technologies, a number of critical steps are required to convert raw intensity measurements into the data relied upon by data analysts,…”
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1131 CHARACTERIZATION OF OBJECTIVE AND SUBJECTIVE SLEEP IN PATIENTS RECEIVING BUPRENORPHINE MAINTENANCE THERAPY FOR OPIOID USE DISORDER by Speed, TJ, Finan, PH, Kowalczyk, WJ, Tyburski, M, Epstein, DH, Preston, KL

“…Abstract Introduction: Sleep disturbances associated with opioid use disorder (OUD) are well recognized. Characterization of sleep abnormalities in individuals…”
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A model selection approach for the identification of quantitative trait loci in experimental crosses by Broman, Karl W., Speed, Terence P.

“…We consider the problem of identifying the genetic loci (called quantitative trait loci (QTLs)) contributing to variation in a quantitative trait, with data on…”
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Mitochondrial related gene expression changes are sensitive to agonal-pH state by Vawter, M P, Tomita, H, Meng, F, Bolstad, B, Li, J, Evans, S, Choudary, P, Atz, M, Shao, L, Neal, C, Walsh, D M, Burmeister, M, Speed, T, Myers, R, Jones, E G, Watson, S J, Akil, H, Bunney, W E

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On the Application of Probability Theory to Agricultural Experiments. Essay on Principles. Section 9 by Splawa-Neyman, Jerzy, Dabrowska, D. M., Speed, T. P.

“…In the portion of the paper translated here, Neyman introduces a model for the analysis of field experiments conducted for the purpose of comparing a number of…”
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