Search Results - "Speake, P. F."

SNAT4 isoform of system A amino acid transporter is expressed in human placenta by Desforges, M, Lacey, H A, Glazier, J D, Greenwood, S L, Mynett, K J, Speake, P F, Sibley, C P

“…The system A amino acid transporter is encoded by three members of the Slc38 gene family, giving rise to three subtypes: Na+-coupled neutral amino acid…”
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Epidermal growth factor and sphingosine-1-phosphate stimulate Na+/H+ exchanger activity in the human placental syncytiotrophoblast by Johnstone, E D, Speake, P F, Sibley, C P

“…The Na+/H+ exchanger (NHE) has a key role in intracellular pH ([pH]i) regulation of the syncytiotrophoblast in the human placenta and may have a role in the…”
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l-Arginine Transport across the Basal Plasma Membrane of the Syncytiotrophoblast of the Human Placenta from Normal and Preeclamptic Pregnancies by Speake, P. F., Glazier, J. D., Ayuk, P. T.-Y., Reade, M., Sibley, C. P., D’Souza, S. W.

“…Cord blood levels of nitrate/nitrite, as a measure of nitric oxide (NO), are generally increased in preeclampsia. As l-arginine is the precursor for NO…”
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Taurine transporter in fetal T lymphocytes and platelets: differential expression and functional activity by Iruloh, C G, D'Souza, S W, Speake, P F, Crocker, I, Fergusson, W, Baker, P N, Sibley, C P, Glazier, J D

“…Transplacental transfer of taurine, a beta-amino acid essential for fetal and neonatal development, constitutes the primary source of taurine for the fetus…”
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Activity and expression of Na+/H+ exchanger isoforms in the syncytiotrophoblast of the human placenta by Speake, P F, Mynett, K J, Glazier, J D, Greenwood, S L, Sibley, C P

“…The purpose of this study was to compare Na+/H+ exchanger (NHE) activity in the microvillous (MVM) and basal (BM) plasma membrane of the human placental…”
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Oxidants and regulation of K(+)-Cl(-) cotransport in equine red blood cells by Muzyamba, M C, Speake, P F, Gibson, J S

“…The effect of oxidants on K(+)-Cl(-) cotransport (KCC) was investigated in equine red blood cells. Carbon monoxide mimicked O(2). The substituted benzaldehyde,…”
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Differential oxygen sensitivity of the K+‐Cl− cotransporter in normal and sickle human red blood cells by Gibson, J. S., Speake, P. F., Ellory, J. C.

“…1 K+ influx and efflux were measured in normal (HbA) and sickle (HbS) red blood cells to investigate the interaction of swelling, H+ ions and urea with O2 (0…”
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Effect of changes in respiratory blood parameters on equine red blood cell K-Cl cotransporter by Speake, P F, Roberts, C A, Gibson, J S

“…K influx into equine red blood cells (RBCs) was measured using 86Rb as a tracer for K under conditions designed to mimic the changes in respiratory blood…”
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O2 dependence of K+ transport in sickle cells: the effect of different cell populations and the substituted benzaldehyde 12C79 by GIBSON, J. S., KHAN, A, SPEAKE, P. F., ELLORY, J. C.

“…ABSTRACT The molecular basis of sickle cell disease (SCD) is well known but the pathophysiology is poorly understood. It remains intractable to therapy…”
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Aldosterone and Cortisol Acutely Stimulate Na+ /H+ Exchanger Activity in the Syncytiotrophoblast of the Human Placenta: Effect of Fetal Sex by Speake, P.F, Glazier, J.D, Greenwood, S.L, Sibley, C.P

“…Abstract Na+ /H+ exchanger (NHE) activity regulates intracellular pH (pHi ) in the placental syncytiotrophoblast. In other tissues aldosterone and cortisol…”
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Urea-stimulated K-Cl cotransport in equine red blood cells by Speake, P F, Gibson, J S

“…The effect of urea and its interactions with oxygen tension (PO2), cell volume and inhibitors of protein phosphatases/kinases (PP/PK) on the K influx into…”
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Effects of urea and oxygen tension on K flux in sickle cells by Culliford, S J, Ellory, J C, Gibson, J S, Speake, P F

“…K influx and efflux (both ouabain- and bumetanide-resistant) in haemoglobin S-containing red cells (sickle cells) were markedly stimulated by urea (> 0.25 M)…”
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Effect of the substituted benzaldehyde 12C79 on Cl--dependent K+ influx in human red blood cells by Gibson, J S, Speake, P F, Ellory, J C

“…Ouabain- and bumetanide-resistant K+ influx, and haemoglobin (Hb) O2 saturation, were measured in HbA red cells over a range of oxygen tensions (PO2 values) in…”
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Dose-response effects of adrenergic and cholinergic stimulation on atrial natriuretic peptide secretion from beating isolated guinea-pig atria by Speake, P F, Pirie, S C, Kibble, J D, Muneer, A, Taylor, D, Birring, S, Green, R

“…1. The possible role of autonomic neurotransmitters in atrial natriuretic peptide secretion was investigated using spontaneously beating guinea-pig atria in…”
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O 2 dependence of K + transport in sickle cells: the effect of different cell populations and the substituted benzaldehyde 12C79 by GIBSON, J. S., KHAN, A, SPEAKE, P. F., ELLORY, J. C.

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K + transport in red blood cells from human umbilical cord by Gibson, John S., Speake, Paul F., Muzyamba, Morris C., Husain, Fattima, Luckas, Murray C.M., Ellory, J.Clive

“…The current study was designed to characterise K + transport in human fetal red blood cells, containing mainly haemoglobin F (HbF, and termed HbF cells),…”
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Differential oxygen sensitivity of the K+-Cl− cotransporter in normal and sickle human red blood cells by J S Gibson, P F Speake, J C Ellory

“…K + influx and efflux were measured in normal (HbA) and sickle (HbS) red blood cells to investigate the interaction of swelling, H + ions and urea with O 2 (0…”
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Taurine transport into fetal cord blood cells: inhibition by cyclosporine A by Speake, Paul F, Zipitis, Christos S, Houston, Angela, D'Souza, Stephen

“…Pregnant women undergoing long-term organ transplant treatment have an increased incidence of delivering infants with intrauterine growth restriction (IUGR)…”
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