Search Results - "Sparr, Christof"

Catalyst-Controlled Stereoselective Synthesis of Atropisomers by Zilate, Bouthayna, Castrogiovanni, Alessandro, Sparr, Christof

“…Owing to their favorable molecular topology, atropisomers represent particularly valuable chiral scaffolds for numerous applications throughout academic…”
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Organocatalytic Atroposelective Aldol Condensation: Synthesis of Axially Chiral Biaryls by Arene Formation by Link, Achim, Sparr, Christof

“…Axially chiral compounds are of significant importance in modern synthetic chemistry and particularly valuable in drug discovery and development. Nonetheless,…”
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Remote Central‐to‐Axial Chirality Conversion: Direct Atroposelective Ester to Biaryl Transformation by Link, Achim, Sparr, Christof

“…A strategy for the remote central‐to‐axial chirality conversion by simultaneous planarization of an encoding and a transient stereocenter is presented. Based…”
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Ad Hoc Adjustment of Photoredox Properties by the Late-Stage Diversification of Acridinium Photocatalysts by Hutskalova, Valeriia, Sparr, Christof

“…The steadily growing interest in substituting precious-metal photoredox catalysts with organic surrogates is vibrantly sustained by emerging methodologies to…”
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Catalyst Control over Twofold and Higher-Order Stereogenicity by Atroposelective Arene Formation by Schmidt, Tanno A, Sparr, Christof

“…Conspectus Contradictory to the first intuitive impression that forging putatively flat aromatic rings evades stereoisomerism, a striking variety of…”
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Fluorine Conformational Effects in Organocatalysis: An Emerging Strategy for Molecular Design by Zimmer, Lucie E., Sparr, Christof, Gilmour, Ryan

“…Molecular design strategies that profit from the intrinsic stereoelectronic and electrostatic effects of fluorinated organic molecules have mainly been…”
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Cyclopropyl Iminium Activation: Reactivity Umpolung in Enantioselective Organocatalytic Reaction Design by Sparr, Christof, Gilmour, Ryan

“…Trick the iminium! The concept of cyclopropyl iminium activation for the organocatalytic desymmetrization of meso‐cyclopropylcarbaldehydes is presented. A…”
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Stereoselective Arene-Forming Aldol Condensation: Synthesis of Axially Chiral Aromatic Amides by Fäseke, Vincent C., Sparr, Christof

“…The increasing awareness of the importance of amide atropisomers prompts the development of novel strategies for their selective preparation. Described herein…”
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Modulation of Acridinium Organophotoredox Catalysts Guided by Photophysical Studies by Fischer, Christian, Kerzig, Christoph, Zilate, Bouthayna, Wenger, Oliver S, Sparr, Christof

“…Control over redox states and spin multiplicity of photocatalysts throughout a catalytic cycle is crucial for selective and efficient photocatalytic processes…”
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Catalyst control over pentavalent stereocentres by Budeev, Anton, Dong, Jianyang, Häussinger, Daniel, Sparr, Christof

“…A monumental diversity of catalytic methods imparts the ability to select one of two configurations of tetravalent stereocentres. Conversely, catalyst control…”
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Stereoselective Arene-Forming Aldol Condensation: Synthesis of Configurationally Stable Oligo-1,2-naphthylenes by Lotter, Dominik, Neuburger, Markus, Rickhaus, Michel, Häussinger, Daniel, Sparr, Christof

“…Structurally well‐defined oligomers are fundamental for the functionality of natural molecular systems and key for the design of synthetic counterparts…”
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Fluoro-Organocatalysts: Conformer Equivalents as a Tool for Mechanistic Studies by Sparr, Christof, Gilmour, Ryan

“…Fluorine in charge! The fluorine–iminium ion gauche effect has been exploited in the design of conformational probes for organocatalysis (see scheme)…”
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Polyketide Cyclizations for the Synthesis of Polyaromatics by Fäseke, Vincent C., Raps, Felix C., Sparr, Christof

“…The folding and cyclization of poly‐β‐carbonyl chains controlled by the intricate enzymatic polyketide synthase machinery results in a remarkable diversity of…”
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Catalyst-Controlled Stereodivergent Synthesis of Atropisomeric Multiaxis Systems by Lotter, Dominik, Castrogiovanni, Alessandro, Neuburger, Markus, Sparr, Christof

“…Molecular scaffolds with multiple rotationally restricted bonds allow a precise spatial positioning of functional groups. However, their synthesis requires…”
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Stereoselective Arene‐Forming Aldol Condensation: Catalyst‐Controlled Synthesis of Axially Chiral Compounds by Witzig, Reto M., Lotter, Dominik, Fäseke, Vincent C., Sparr, Christof

“…The fundamental role that aldol chemistry adopts in various disciplines, such as stereoselective catalysis or the biosynthesis of aromatic polyketides,…”
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Diastereodivergent Catalysis by Moser, Daniel, Schmidt, Tanno A., Sparr, Christof

“…Alongside enantioselective catalysis, synthetic chemists are often confronted by the challenge of achieving catalyst control over the relative configuration to…”
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Atroposelective synthesis of tetra-ortho-substituted biaryls by catalyst-controlled non-canonical polyketide cyclizations by Witzig, Reto M., Fäseke, Vincent C., Häussinger, Daniel, Sparr, Christof

“…The cyclization of poly-β-carbonyl-substrates controlled by polyketide synthases intricately governs the biosynthesis of a wide range of aromatic polyketides…”
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Catalyst control over sixfold stereogenicity by Wu, Xingxing, Witzig, Reto M., Beaud, Rodolphe, Fischer, Christian, Häussinger, Daniel, Sparr, Christof

“…Achieving control over higher-order stereogenicity is a long-standing goal in stereoselective catalysis to deliberately address more than a twofold number of…”
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Fluorine-Iminium Ion Gauche Effect: Proof of Principle and Application to Asymmetric Organocatalysis by Sparr, Christof, Schweizer, W. Bernd, Senn, Hans Martin, Gilmour, Ryan

“…The gauche effect that is induced upon reversible formation of an iminium ion (see structure: green F, blue N) provides a powerful method for the…”
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Interface-rich Aqueous Systems for Sustainable Chemical Synthesis by Dainis Kaldre, Fabrice Gallou, Christof Sparr, Michael Parmentier

“…Mimicking an enzyme's exquisite activity and selectivity is a long-standing goal for sustainable chemical method development in aqueous media. The use of…”
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