Search Results - "Spano, Jean Philippe"

A Score to Predict the Clinical Usefulness of Therapeutic Drug Monitoring: Application to Oral Molecular Targeted Therapies in Cancer by Géraud, Arthur, Combarel, David, Funck‐Brentano, Christian, Beaulieu, Quentin, Zahr, Noël, Broutin, Sophie, Spano, Jean‐Philippe, Massard, Christophe, Besse, Benjamin, Gougis, Paul

“…Therapeutic drug monitoring (TDM) involves measuring and interpreting drug concentrations in biological fluids to adjust drug dosages. In onco‐hematology, TDM…”
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Immune checkpoint inhibitor-induced myositis, the earliest and most lethal complication among rheumatic and musculoskeletal toxicities by Allenbach, Yves, Anquetil, Céline, Manouchehri, Ali, Benveniste, Olivier, Lambotte, Olivier, Lebrun-Vignes, Bénédicte, Spano, Jean-Philippe, Ederhy, Stéphane, Klatzmann, David, Rosenzwajg, Michelle, Fautrel, Bruno, Cadranel, Jacques, Johnson, Douglas B., Moslehi, Javid J., Salem, Joe-Elie

“…In addition to restoring anti-tumor immune responses, immune checkpoint inhibitors (ICI) may also induce immune-related adverse events (irAE) that can affect…”
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Cardiac arrhythmia considerations of hormone cancer therapies by Barber, Mary, Nguyen, Lee S, Wassermann, Johanna, Spano, Jean-Philippe, Funck-Brentano, Christian, Salem, Joe-Elie

“…Abstract Breast and prostate cancers are among the most prevalent cancers worldwide. Oestradiol and progesterone are major drivers for breast cancer…”
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Comprehensive analysis of long non-coding RNAs in human breast cancer clinical subtypes by Su, Xiaoping, Malouf, Gabriel G, Chen, Yunxin, Zhang, Jianping, Yao, Hui, Valero, Vicente, Weinstein, John N, Spano, Jean-Philippe, Meric-Bernstam, Funda, Khayat, David, Esteva, Francisco J

“…Accumulating evidence highlights the potential role of long non-coding RNAs (lncRNAs) as biomarkers and therapeutic targets in solid tumors. However, the role…”
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Comprehensive integrative profiling of upper tract urothelial carcinomas by Su, Xiaoping, Lu, Xiaofan, Bazai, Sehrish Khan, Compérat, Eva, Mouawad, Roger, Yao, Hui, Rouprêt, Morgan, Spano, Jean-Philippe, Khayat, David, Davidson, Irwin, Tannir, Nizar N, Yan, Fangrong, Malouf, Gabriel G

“…Crosstalk between genetic, epigenetic, and immune alterations in upper tract urothelial carcinomas and their role in shaping muscle invasiveness and patient…”
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Neurocognitive function impairment after whole brain radiotherapy for brain metastases: actual assessment by Tallet, Agnes V, Azria, David, Barlesi, Fabrice, Spano, Jean-Philippe, Carpentier, Antoine F, Gonçalves, Antony, Metellus, Philippe

“…Whole brain radiation therapy (WBRT) is an effective treatment in brain metastases and, when combined with local treatments such as surgery and stereotactic…”
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Outcomes and Prognostic Factors in Radioiodine Refractory Differentiated Thyroid Carcinomas by Wassermann, Johanna, Bernier, Marie‐Odile, Spano, Jean‐Philippe, Lepoutre‐Lussey, Charlotte, Buffet, Camille, Simon, Jean‐Marc, Ménégaux, Fabrice, Tissier, Frédérique, Leban, Monique, Leenhardt, Laurence

“…Background. Outcomes vary among patients with radioiodine refractory (RR) differentiated thyroid cancer (DTC). The prognostic factors for survival are not…”
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POD1UM-303/InterAACT 2: A phase III, global, randomized, double-blind study of retifanlimab or placebo plus carboplatin–paclitaxel in patients with locally advanced or metastatic squamous cell anal carcinoma by Rao, Sheela, Jones, Mark, Bowman, Jill, Tian, Chuan, Spano, Jean-Philippe

“…Background Squamous carcinoma of the anal canal (SCAC) is a human papillomavirus (HPV)-driven cancer with poor prognosis in locally advanced or recurrent…”
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Current and emerging targeted therapies for metastatic breast cancer by Perez, Edith A., Spano, Jean‐Philippe

“…The success of endocrine therapies for hormone receptor‐positive breast cancer and trastuzumab and lapatinib for targeting human epidermal growth factor…”
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A French cohort for assessing COVID-19 vaccine responses in specific populations by Loubet, Paul, Wittkop, Linda, Tartour, Eric, Parfait, Beatrice, Barrou, Benoit, Blay, Jean-Yves, Hourmant, Maryvonne, Lachâtre, Marie, Laplaud, David-Axel, Laville, Martine, Laviolle, Bruno, Lelievre, Jean-Daniel, Morel, Jacques, Nguyen, Stéphanie, Spano, Jean-Philippe, Terrier, Benjamin, Thiebaut, Anne, Viallard, Jean-Francois, Vrtovsnik, François, de Lamballerie, Xavier, Launay, Odile

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High p95HER2/HER2 Ratio Associated With Poor Outcome in Trastuzumab-Treated HER2-Positive Metastatic Breast Cancer NCCTG N0337 and NCCTG 98-32-52 (Alliance) by Chumsri, Saranya, Sperinde, Jeff, Liu, Heshan, Gligorov, Joseph, Spano, Jean-Philippe, Antoine, Martine, Moreno Aspitia, Alvaro, Tan, Winston, Winslow, John, Petropoulos, Christos J, Chenna, Ahmed, Bates, Michael, Weidler, Jodi Marie, Huang, Weidong, Dueck, Amylou, Perez, Edith A

“…p95HER2 is a truncated form of HER2 that confers resistance to trastuzumab , but clinical results have been conflicting to date. Given that p95HER2 levels…”
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Brain Metastases and Place of Antiangiogenic Therapies in Alveolar Soft Part Sarcoma: A Retrospective Analysis of the French Sarcoma Group by Malouf, Gabriel G., Beinse, Guillaume, Adam, Julien, Mir, Olivier, Chamseddine, Ali N., Terrier, Philippe, Honore, Charles, Spano, Jean‐Philippe, Italiano, Antoine, Kurtz, Jean‐Emmanuel, Coindre, Jean‐Michel, Blay, Jean‐Yves, Le Cesne, Axel

“…Background Alveolar soft part sarcoma (ASPS) is a rare sarcoma characterized by a slow evolution, brain metastasis (BM), and resistance to doxorubicin…”
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Trends in survival after cancer diagnosis among HIV‐infected individuals between 1992 and 2009. Results from the FHDH‐ANRS CO4 cohort by Hleyhel, Mira, Belot, Aurélien, Bouvier, Anne‐Marie, Tattevin, Pierre, Pacanowski, Jérôme, Genet, Philippe, De Castro, Nathalie, Berger, Jean‐Luc, Dupont, Caroline, Lavolé, Armelle, Pradier, Christian, Salmon, Dominique, Simon, Anne, Martinez, Valérie, Spano, Jean‐Philippe, Costagliola, Dominique, Grabar, Sophie

“…Although the decline in cancer mortality rates with the advent of combination antiretroviral therapy (cART) in HIV‐infected individuals can be mostly explained…”
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NSD1 Inactivation and SETD2 Mutation Drive a Convergence toward Loss of Function of H3K36 Writers in Clear Cell Renal Cell Carcinomas by Su, Xiaoping, Zhang, Jianping, Mouawad, Roger, Compérat, Eva, Rouprêt, Morgan, Allanic, Frederick, Parra, Jérôme, Bitker, Marc-Olivier, Thompson, Erika J, Gowrishankar, Banumathy, Houldsworth, Jane, Weinstein, John N, Tost, Jorg, Broom, Bradley M, Khayat, David, Spano, Jean-Philippe, Tannir, Nizar M, Malouf, Gabriel G

“…Extensive dysregulation of chromatin-modifying genes in clear cell renal cell carcinoma (ccRCC) has been uncovered through next-generation sequencing. However,…”
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Safety and effectiveness of cervical vertebroplasty: report of a large cohort and systematic review by Clarençon, Frédéric, Fahed, Robert, Cormier, Evelyne, Haffaf, Idriss, Spano, Jean-Philippe, Shotar, Eimad, Premat, Kévin, Bonaccorsi, Raphael, Degos, Vincent, Chiras, Jacques

“…Purpose To evaluate retrospectively safety and effectiveness of cervical vertebroplasty (cVP) based on a single-center large cohort. Materials and methods All…”
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DNA Methylation Signature Reveals Cell Ontogeny of Renal Cell Carcinomas by Malouf, Gabriel G, Su, Xiaoping, Zhang, Jianping, Creighton, Chad J, Ho, Thai H, Lu, Yue, Raynal, Noël J-M, Karam, Jose A, Tamboli, Pheroze, Allanick, Frederick, Mouawad, Roger, Spano, Jean-Philippe, Khayat, David, Wood, Christopher G, Jelinek, Jaroslav, Tannir, Nizar M

“…DNA methylation is a heritable covalent modification that is developmentally regulated and is critical in tissue-type definition. Although genotype-phenotype…”
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Efficacy of gemcitabine plus axitinib compared with gemcitabine alone in patients with advanced pancreatic cancer: an open-label randomised phase II study by Spano, Jean-Philippe, Prof, Chodkiewicz, Catherine, MD, Maurel, Joan, MD, Wong, Ralph, MD, Wasan, Harpreet, MD, Barone, Carlo, Prof, Létourneau, Richard, MD, Bajetta, Emilio, MD, Pithavala, Yazdi, PhD, Bycott, Paul, DrPh, Trask, Peter, PhD, Liau, Katherine, BS, Ricart, Alejandro D, MD, Kim, Sinil, MD, Rixe, Olivier, Prof

“…Summary Background Axitinib (AG-013736) is a potent and selective oral inhibitor of vascular endothelial growth factor receptors 1, 2, and 3, which have an…”
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Molecular characterization of sarcomatoid clear cell renal cell carcinoma unveils new candidate oncogenic drivers by Malouf, Gabriel G., Flippot, Ronan, Dong, Yiyu, Dinatale, Renzo G., Chen, Ying-Bei, Su, Xiaoping, Compérat, Eva, Rouprêt, Morgan, Mano, Roy, Blum, Kyle A., Yao, Hui, Mouawad, Roger, Spano, Jean-Philippe, Khayat, David, Karam, Jose A., Ho, Thai H., Tickoo, Satish K., Russo, Paul, Hsieh, James J., Tannir, Nizar M., Hakimi, Abraham A.

“…Sarcomatoid clear-cell renal cell carcinomas (sRCC) are associated with dismal prognosis. Genomic alterations associated with sarcomatoid dedifferentiation are…”
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The spectrum of malignancies in HIV‐infected patients in 2006 in France: The ONCOVIH study by Lanoy, Emilie, Spano, Jean‐Philippe, Bonnet, Fabrice, Guiguet, Marguerite, Boué, François, Cadranel, Jacques, Carcelain, Guislaine, Couderc, Louis‐Jean, Frange, Pierre, Girard, Pierre‐Marie, Oksenhendler, Eric, Poizot‐Martin, Isabelle, Semaille, Caroline, Agut, Henri, Katlama, Christine, Costagliola, Dominique

“…Since no large descriptive studies of incident cancers in HIV‐infected patients are available in France, the nationwide cross‐sectional ONCOVIH study aimed to…”
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Treatment for metastatic malignant melanoma: Old drugs and new strategies by Mouawad, Roger, Sebert, Marie, Michels, Judith, Bloch, Joel, Spano, Jean-Philippe, Khayat, David

“…Abstract The number of melanoma cases worldwide is increasing faster than any other cancer and remains one of the most treatment-refractory malignancies…”
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