Search Results - "Spangler, Matthew"

The Benefit of a National Genomic Testing Scheme by Berry, Donagh P, Spangler, Matthew L

“…Although a significant cost, genotyping an entire population offers many benefits, many of which can reduce the workload and effort in decision-making on farm…”
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Epigenetic clock and methylation study of oocytes from a bovine model of reproductive aging by Kordowitzki, Paweł, Haghani, Amin, Zoller, Joseph A., Li, Caesar Z., Raj, Ken, Spangler, Matthew L., Horvath, Steve

“…Cattle are an attractive animal model of fertility in women due to their high degree of similarity relative to follicle selection, embryo cleavage, blastocyst…”
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Influence of host genetics in shaping the rumen bacterial community in beef cattle by Abbas, Waseem, Howard, Jeremy T., Paz, Henry A., Hales, Kristin E., Wells, James E., Kuehn, Larry A., Erickson, Galen E., Spangler, Matthew L., Fernando, Samodha C.

“…In light of recent host-microbial association studies, a consensus is evolving that species composition of the gastrointestinal microbiota is a polygenic trait…”
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Rumen bacterial community structure impacts feed efficiency in beef cattle by Paz, Henry A, Hales, Kristin E, Wells, James E, Kuehn, Larry A, Freetly, Harvey C, Berry, Elaine D, Flythe, Michael D, Spangler, Matthew L, Fernando, Samodha C

“…Abstract The importance of the rumen microbiota on nutrient cycling to the animal is well recognized; however, our understanding of the influence of the rumen…”
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Strategies for accommodating gene-edited sires and their descendants in genetic evaluations by Sanglard, Leticia P, See, Garret M, Spangler, Matthew L

“…Abstract Gene editing has the potential to expedite the rate of genetic gain for complex traits. However, changing nucleotides (i.e., QTN) in the genome can…”
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Impact of inclusion rates of crossbred phenotypes and genotypes in nucleus selection programs by See, Garrett M, Mote, Benny E, Spangler, Matthew L

“…Abstract Numerous methods have been suggested to incorporate crossbred (CB) phenotypes and genotypes into swine selection programs, yet little research has…”
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Ultra-Fast List-Mode Reconstruction of Short PET Frames and Example Applications by Spangler-Bickell, Matthew G, Deller, Timothy W, Bettinardi, Valentino, Jansen, Floris

“…Standard clinical reconstructions usually require several minutes to complete, and this time is mostly independent of the duration of the data being…”
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Categorization of birth weight phenotypes for inclusion in genetic evaluations using a deep neural network by Ribeiro, Andre, Golden, Bruce L, Spangler, Matthew L

“…Abstract Birth weight (BW) serves as a valuable indicator of the economically relevant trait of calving ease (CE), and erroneous data collection for BW could…”
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Bias in variance component estimation in swine crossbreeding schemes using selective genotyping and phenotyping strategies by See, Garrett M, Mote, Benny E, Spangler, Matthew L

“…Abstract Selective genotyping of crossbred (CB) animals to include in traditionally purebred (PB) dominated genetic evaluations has been shown to provide an…”
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Influence of environmental factors and genetic variation on mitochondrial DNA copy number by Sanglard, Leticia P, Kuehn, Larry A, Snelling, Warren M, Spangler, Matthew L

“…Mitochondrial DNA copy number (mtDNA CN) has been shown to be highly heritable and associated with traits of interest in humans. However, studies are lacking…”
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Influence of environmental factors and genetic variation on mitochondrial DNA copy number by Sanglard, Leticia P, Kuehn, Larry A, Snelling, Warren M, Spangler, Matthew L

“…Abstract Mitochondrial DNA copy number (mtDNA CN) has been shown to be highly heritable and associated with traits of interest in humans. However, studies are…”
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Do stronger measures of genomic connectedness enhance prediction accuracies across management units? by Yu, Haipeng, Spangler, Matthew L, Lewis, Ronald M, Morota, Gota

“…Genetic connectedness assesses the extent to which estimated breeding values can be fairly compared across management units. Ranking of individuals across…”
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Selective genotyping and phenotypic data inclusion strategies of crossbred progeny for combined crossbred and purebred selection in swine breeding by See, Garrett M, Mote, Benny E, Spangler, Matthew L

“…Abstract Inclusion of crossbred (CB) data into traditionally purebred (PB) genetic evaluations has been shown to increase the response in CB performance…”
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DNA methylation profile in beef cattle is influenced by additive genetics and age by Ribeiro, André Mauric F., Sanglard, Leticia P., Wijesena, Hiruni R., Ciobanu, Daniel C., Horvath, Steve, Spangler, Matthew L.

“…DNA methylation (DNAm) has been considered a promising indicator of biological age in mammals and could be useful to increase the accuracy of phenotypic…”
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Imputation of non-genotyped F1 dams to improve genetic gain in swine crossbreeding programs by See, Garrett M, Fix, Justin S, Schwab, Clint R, Spangler, Matthew L

“…Abstract This study investigated using imputed genotypes from non-genotyped animals which were not in the pedigree for the purpose of genetic selection and…”
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An autosomal recessive variant in PYGM causes myophosphorylase deficiency in Red Angus composite cattle by Batt, Mackenzie C, Venzor, Leila G, Gardner, Keri, Reith, Rachel R, Roberts, Kelsey A, Herrera, Nicolas J, Fuller, Anna M, Sullivan, Gary A, Mulliniks, J Travis, Spangler, Matthew L, Valberg, Stephanie J, Steffen, David J, Petersen, Jessica L

“…Between 2020 and 2022, eight calves in a Nebraska herd (composite Simmental, Red Angus, Gelbvieh) displayed exercise intolerance during forced activity. In…”
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Genomic prediction using pooled data in a single-step genomic best linear unbiased prediction framework by Baller, Johnna L, Kachman, Stephen D, Kuehn, Larry A, Spangler, Matthew L

“…Abstract Economically relevant traits are routinely collected within the commercial segments of the beef industry but are rarely included in genetic…”
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Breed and heterotic effects for mature weight in beef cattle by Zimmermann, Madeline J, Kuehn, Larry A, Spangler, Matthew L, Thallman, R Mark, Snelling, Warren M, Lewis, Ronald M

“…Cow mature weight (MWT) is heritable and affects the costs and efficiency of a breeding operation. Cow weight is also influenced by the environment, and the…”
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Intraspecific polymorphism, interspecific divergence, and the origins of function-altering mutations in deer mouse hemoglobin by Natarajan, Chandrasekhar, Hoffmann, Federico G, Lanier, Hayley C, Wolf, Cole J, Cheviron, Zachary A, Spangler, Matthew L, Weber, Roy E, Fago, Angela, Storz, Jay F

“…Major challenges for illuminating the genetic basis of phenotypic evolution are to identify causative mutations, to quantify their functional effects, to trace…”
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Genome-wide association study for feed efficiency and growth traits in U.S. beef cattle by Seabury, Christopher M, Oldeschulte, David L, Saatchi, Mahdi, Beever, Jonathan E, Decker, Jared E, Halley, Yvette A, Bhattarai, Eric K, Molaei, Maral, Freetly, Harvey C, Hansen, Stephanie L, Yampara-Iquise, Helen, Johnson, Kristen A, Kerley, Monty S, Kim, JaeWoo, Loy, Daniel D, Marques, Elisa, Neibergs, Holly L, Schnabel, Robert D, Shike, Daniel W, Spangler, Matthew L, Weaber, Robert L, Garrick, Dorian J, Taylor, Jeremy F

“…Single nucleotide polymorphism (SNP) arrays for domestic cattle have catalyzed the identification of genetic markers associated with complex traits for…”
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