Search Results - "Spangler, E"

Catalytic Asymmetric Synthesis of Pyrroloindolines via a Rhodium(II)-Catalyzed Annulation of Indoles by Spangler, Jillian E, Davies, Huw M. L

“…Herein we report the synthesis of pyrrolo­indolines via a catalytic enantio­selective formal [3+2] cycloaddition of C(3)-substituted indoles. This methodology…”
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Strain-release amination by Gianatassio, Ryan, Lopchuk, Justin M., Wang, Jie, Pan, Chung-Mao, Malins, Lara R., Prieto, Liher, Brandt, Thomas A., Collins, Michael R., Gallego, Gary M., Sach, Neal W., Spangler, Jillian E., Zhu, Huichin, Zhu, Jinjiang, Baran, Phil S.

“…To optimize drug candidates, modern medicinal chemists are increasingly turning to an unconventional structural motif: small, strained ring systems. However,…”
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Conversion of Cyclic Ketones to 2,3-Fused Pyrroles and Substituted Indoles by Alford, Joshua S, Spangler, Jillian E, Davies, Huw M. L

“…A highly effective synthesis of 2,3-fused pyrroles from cyclic ketones has been achieved. The transformation includes a rhodium-catalyzed reaction of…”
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Strain-Release Heteroatom Functionalization: Development, Scope, and Stereospecificity by Lopchuk, Justin M, Fjelbye, Kasper, Kawamata, Yu, Malins, Lara R, Pan, Chung-Mao, Gianatassio, Ryan, Wang, Jie, Prieto, Liher, Bradow, James, Brandt, Thomas A, Collins, Michael R, Elleraas, Jeff, Ewanicki, Jason, Farrell, William, Fadeyi, Olugbeminiyi O, Gallego, Gary M, Mousseau, James J, Oliver, Robert, Sach, Neal W, Smith, Jason K, Spangler, Jillian E, Zhu, Huichin, Zhu, Jinjiang, Baran, Phil S

“…Driven by the ever-increasing pace of drug discovery and the need to push the boundaries of unexplored chemical space, medicinal chemists are routinely turning…”
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Comparison of GEOS-5 AGCM planetary boundary layer depths computed with various definitions by McGrath-Spangler, E. L, Molod, A

“…Accurate models of planetary boundary layer (PBL) processes are important for forecasting weather and climate. The present study compares seven methods of…”
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Rh(iii)-catalyzed C-H olefination of N -pentafluoroaryl benzamides using air as the sole oxidant by Lu, Yi, Wang, Huai-Wei, Spangler, Jillian E, Chen, Kai, Cui, Pei-Pei, Zhao, Yue, Sun, Wei-Yin, Yu, Jin-Quan

“…The oxidative olefination of a broad array of arenes and heteroarenes with a variety of activated and unactivated olefins has be achieved a…”
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Impact of planetary boundary layer turbulence on model climate and tracer transport by McGrath-Spangler, E L, Molod, A, Ott, L E, Pawson, S

“…Planetary boundary layer (PBL) processes are important for weather, climate, and tracer transport and concentration. One measure of the strength of these…”
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Quantifying stream-loss recovery in a spring using dual-tracer injections in the Snake Creek drainage, Great Basin National Park, Nevada, USA by Humphrey, C. Eric, Gardner, Philip M., Spangler, Lawrence E., Nelson, Nora C., Toran, Laura, Solomon, D. Kip

“…Simultaneous short-pulse injections of two tracers (sodium bromide [Br – ] and fluorescein dye) were made in a losing reach of Snake Creek in Great Basin…”
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Climate Change-Driven Cumulative Mountain Pine Beetle-Caused Whitebark Pine Mortality in the Greater Yellowstone Ecosystem by William W. Macfarlane, Brian Howell, Jesse A. Logan, Ally L. Smith, Cashe C. Rasmussen, Robert E. Spangler

“…An aerial survey method called the Landscape Assessment System (LAS) was used to assess mountain pine beetle (Dendroctonus ponderosae)-caused mortality of…”
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A Propulsion Neuroprosthesis Improves Overground Walking in Community-Dwelling Individuals After Stroke by Choe, Dabin K., Aiello, Ashlyn J., Spangler, Johanna E., Walsh, Conor J., Awad, Louis N.

“…Functional electrical stimulation (FES) is a common neuromotor intervention whereby electrically evoked dorsiflexor muscle contractions assist foot clearance…”
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The impact of a boundary layer height formulation on the GEOS-5 model climate by McGrath-Spangler, EL

“…Planetary boundary layer (PBL) processes are important for the estimation of surface-atmosphere exchanges that impact global climate. One way of characterizing…”
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The effects of age and lipopolysaccharide (LPS)-mediated peripheral inflammation on numbers of central catecholaminergic neurons by Mouton, P.R, Kelley-Bell, B, Tweedie, D, Spangler, E.L, Perez, E, Carlson, O.D, Short, R.G, deCabo, R, Chang, J, Ingram, D.K, Li, Y, Greig, N.H

“…Abstract Parkinson's disease (PD), an age-related movement disorder, is characterized by severe catecholaminergic neuron loss in the substantia nigra pars…”
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A nature-inspired Diels–Alder reaction facilitates construction of the bicyclo[2.2.2]octane core of andibenin B by Spangler, Jillian E., Sorensen, Erik J.

“…A rapid synthesis of the bicyclo[2.2.2]octane core of andibenin B via a nature-inspired intramolecular [4+2] cycloaddition is described. This cycloaddition…”
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Ligand-Controlled C(sp3)–H Arylation and Olefination in Synthesis of Unnatural Chiral α–Amino Acids by He, Jian, Li, Suhua, Deng, Youqian, Fu, Haiyan, Laforteza, Brian N., Spangler, Jillian E., Homs, Anna, Yu, Jin-Quan

“…The use of ligands to tune the reactivity and selectivity of transition metal catalysts for C(sp3)–H bond functionalization is a central challenge in synthetic…”
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Retracted: The impact of a boundary layer height formulation on the GEOS‐5 model climate by McGrath‐Spangler, E. L.

“…Planetary boundary layer (PBL) processes are important for the estimation of surface‐atmosphere exchanges that impact global climate. One way of characterizing…”
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Hindered dialkyl ether synthesis with electrogenerated carbocations by Xiang, Jinbao, Shang, Ming, Kawamata, Yu, Lundberg, Helena, Reisberg, Solomon H., Chen, Miao, Mykhailiuk, Pavel, Beutner, Gregory, Collins, Michael R., Davies, Alyn, Del Bel, Matthew, Gallego, Gary M., Spangler, Jillian E., Starr, Jeremy, Yang, Shouliang, Blackmond, Donna G., Baran, Phil S.

“…Hindered ethers are of high value for various applications; however, they remain an underexplored area of chemical space because they are difficult to…”
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Simplified, standardized methods to assess the accuracy of clinical cancer staging by Wu, Dolly Y., Spangler, Ann E., Vo, Dat T., de Hoyos, Alberto, Seiler, Stephen J.

“…•Introduce simple, intuitive methods to assess and monitor accuracy of clinical cancer staging to help hospitals improve staging and standardize reporting of…”
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α‑Arylation of Saturated Azacycles and N‑Methylamines via Palladium(II)-Catalyzed C(sp3)–H Coupling by Spangler, Jillian E, Kobayashi, Yoshihisa, Verma, Pritha, Wang, Dong-Hui, Yu, Jin-Quan

“…Pd­(II)-catalyzed α-C­(sp3)–H arylation of pyrrolidines, piperidines, azepanes, and N-methylamines with arylboronic acids has been developed for the first…”
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Association of obesity with tumor characteristics and treatment failure of prostate cancer in African-American and European American men by Spangler, E, Zeigler-Johnson, C M, Coomes, M, Malkowicz, S B, Wein, A, Rebbeck, T R

“…The impact of body mass index on tumor characteristics and treatment failure in prostate cancer is not well understood in diverse ethnic groups. We evaluated…”
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Organic chemistry. Strain-release amination by Gianatassio, Ryan, Lopchuk, Justin M, Wang, Jie, Pan, Chung-Mao, Malins, Lara R, Prieto, Liher, Brandt, Thomas A, Collins, Michael R, Gallego, Gary M, Sach, Neal W, Spangler, Jillian E, Zhu, Huichin, Zhu, Jinjiang, Baran, Phil S

“…To optimize drug candidates, modern medicinal chemists are increasingly turning to an unconventional structural motif: small, strained ring systems. However,…”
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