Search Results - "Spampinato, Antonio"

The trophic effect of nerve growth factor in primary cultures of rat hippocampal neurons is associated to an anti‐inflammatory and immunosuppressive transcriptional program by Maino, Barbara, Spampinato, Antonio G., Severini, Cinzia, Petrella, Carla, Ciotti, Maria Teresa, D'Agata, Velia, Calissano, Pietro, Cavallaro, Sebastiano

“…Nerve growth factor, the prototype of a family of neurotrophins, elicits differentiation and survival of peripheral and central neuronal cells. Although its…”
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Discovering Entities Similarities in Biological Networks Using a Hybrid Immune Algorithm by Scollo, Rocco A., Spampinato, Antonio G., Fargetta, Georgia, Cutello, Vincenzo, Pavone, Mario

“…Disease phenotypes are generally caused by the failure of gene modules which often have similar biological roles. Through the study of biological networks, it…”
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Neuroinflammation and ALS: Transcriptomic Insights into Molecular Disease Mechanisms and Therapeutic Targets by Morello, Giovanna, Cavallaro, Sebastiano, Spampinato, Antonio Gianmaria

“…Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting the motor nervous system. Despite the mechanism underlying motor neuron death is…”
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Integrative multi-omic analysis identifies new drivers and pathways in molecularly distinct subtypes of ALS by Morello, Giovanna, Guarnaccia, Maria, Spampinato, Antonio Gianmaria, Salomone, Salvatore, D’Agata, Velia, Conforti, Francesca Luisa, Aronica, Eleonora, Cavallaro, Sebastiano

“…Amyotrophic lateral sclerosis (ALS) is an incurable and fatal neurodegenerative disease. Increasing the chances of success for future clinical strategies…”
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Molecular Taxonomy of Sporadic Amyotrophic Lateral Sclerosis Using Disease-Associated Genes by Morello, Giovanna, Spampinato, Antonio Gianmaria, Cavallaro, Sebastiano

“…Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by selective loss of upper and lower motor neurons. Despite intensive…”
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Cx26 partial loss causes accelerated presbycusis by redox imbalance and dysregulation of Nfr2 pathway by Fetoni, Anna Rita, Zorzi, Veronica, Paciello, Fabiola, Ziraldo, Gaia, Peres, Chiara, Raspa, Marcello, Scavizzi, Ferdinando, Salvatore, Anna Maria, Crispino, Giulia, Tognola, Gabriella, Gentile, Giulia, Spampinato, Antonio Gianmaria, Cuccaro, Denis, Guarnaccia, Maria, Morello, Giovanna, Van Camp, Guy, Fransen, Erik, Brumat, Marco, Girotto, Giorgia, Paludetti, Gaetano, Gasparini, Paolo, Cavallaro, Sebastiano, Mammano, Fabio

“…Mutations in GJB2, the gene that encodes connexin 26 (Cx26), are the most common cause of sensorineural hearing impairment. The truncating variant 35delG,…”
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Taxonomy Meets Neurology, the Case of Amyotrophic Lateral Sclerosis by Morello, Giovanna, Spampinato, Antonio Gianmaria, Conforti, Francesca Luisa, Cavallaro, Sebastiano

“…Recent landmark publications from our research group outline a transformative approach to defining, studying and treating amyotrophic lateral sclerosis (ALS)…”
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Histaminergic transmission slows progression of amyotrophic lateral sclerosis by Apolloni, Savina, Amadio, Susanna, Fabbrizio, Paola, Morello, Giovanna, Spampinato, Antonio Gianmaria, Latagliata, Emanuele Claudio, Salvatori, Illari, Proietti, Daisy, Ferri, Alberto, Madaro, Luca, Puglisi‐Allegra, Stefano, Cavallaro, Sebastiano, Volonté, Cinzia

“…Background Histamine is an immune modulator, neuroprotective, and remyelinating agent, beneficially acting on skeletal muscles and promoting anti‐inflammatory…”
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Transcriptional Profiles of Cell Fate Transitions Reveal Early Drivers of Neuronal Apoptosis and Survival by Morello, Giovanna, Villari, Ambra, Spampinato, Antonio Gianmaria, La Cognata, Valentina, Guarnaccia, Maria, Gentile, Giulia, Ciotti, Maria Teresa, Calissano, Pietro, D'Agata, Velia, Severini, Cinzia, Cavallaro, Sebastiano

“…Neuronal apoptosis and survival are regulated at the transcriptional level. To identify key genes and upstream regulators primarily responsible for these…”
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miRNA and mRNA Profiling Links Connexin Deficiency to Deafness via Early Oxidative Damage in the Mouse Stria Vascularis by Gentile, Giulia, Paciello, Fabiola, Zorzi, Veronica, Spampinato, Antonio Gianmaria, Guarnaccia, Maria, Crispino, Giulia, Tettey-Matey, Abraham, Scavizzi, Ferdinando, Raspa, Marcello, Fetoni, Anna Rita, Cavallaro, Sebastiano, Mammano, Fabio

“…Pathogenic mutations in the non-syndromic hearing loss and deafness 1 (DFNB1) locus are the primary cause of monogenic inheritance for prelingual hearing loss…”
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Random search immune algorithm for community detection by Spampinato, Antonio G., Scollo, Rocco A., Cutello, Vincenzo, Pavone, Mario

“…Community detection is a prominent research topic in Complex Network Analysis, and it constitutes an important research field on all those areas where complex…”
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Omics-based exploration and functional validation of neurotrophic factors and histamine as therapeutic targets in ALS by Volonté, Cinzia, Morello, Giovanna, Spampinato, Antonio Gianmaria, Amadio, Susanna, Apolloni, Savina, D’Agata, Velia, Cavallaro, Sebastiano

“…•ALS is a rare progressive, chronically debilitating motor neuron disease with no cure.•“Omics” approaches provide a novel clue for more comprehensive…”
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Genetic investigation of amyotrophic lateral sclerosis patients in south Italy: a two-decade analysis by Ungaro, Carmine, Sprovieri, Teresa, Morello, Giovanna, Perrone, Benedetta, Spampinato, Antonio Gianmaria, Simone, Isabella Laura, Trojsi, Francesca, Monsurrò, Maria Rosaria, Spataro, Rossella, La Bella, Vincenzo, Andò, Sebastiano, Cavallaro, Sebastiano, Conforti, Francesca Luisa

“…Amyotrophic lateral sclerosis (ALS) is a multifactorial disease characterized by the interplay of genetic and environmental factors. In the majority of cases,…”
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Deletion of Voltage-Dependent Anion Channel 1 knocks mitochondria down triggering metabolic rewiring in yeast by Magrì, Andrea, Di Rosa, Maria Carmela, Orlandi, Ivan, Guarino, Francesca, Reina, Simona, Guarnaccia, Maria, Morello, Giovanna, Spampinato, Antonio, Cavallaro, Sebastiano, Messina, Angela, Vai, Marina, De Pinto, Vito

“…The Voltage-Dependent Anion-selective Channel (VDAC) is the pore-forming protein of mitochondrial outer membrane, allowing metabolites and ions exchanges. In…”
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Selection and Prioritization of Candidate Drug Targets for Amyotrophic Lateral Sclerosis Through a Meta-Analysis Approach by Morello, Giovanna, Spampinato, Antonio Gianmaria, Conforti, Francesca Luisa, D’Agata, Velia, Cavallaro, Sebastiano

“…Amyotrophic lateral sclerosis (ALS) is a progressive and incurable neurodegenerative disease. Although several compounds have shown promising results in…”
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Copy Number Variations in Amyotrophic Lateral Sclerosis: Piecing the Mosaic Tiles Together through a Systems Biology Approach by Morello, Giovanna, Guarnaccia, Maria, Spampinato, Antonio Gianmaria, La Cognata, Valentina, D’Agata, Velia, Cavallaro, Sebastiano

“…Amyotrophic lateral sclerosis (ALS) is a devastating and still untreatable motor neuron disease. Despite the molecular mechanisms underlying ALS pathogenesis…”
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Genomic Portrait of a Sporadic Amyotrophic Lateral Sclerosis Case in a Large Spinocerebellar Ataxia Type 1 Family by Morello, Giovanna, Gentile, Giulia, Spataro, Rossella, Spampinato, Antonio Gianmaria, Guarnaccia, Maria, Salomone, Salvatore, La Bella, Vincenzo, Conforti, Francesca Luisa, Cavallaro, Sebastiano

“…Background: Repeat expansions in the spinocerebellar ataxia type 1 (SCA1) gene ATXN1 increases the risk for amyotrophic lateral sclerosis (ALS), supporting a…”
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22% efficiency module combining Silicon Heterojunction Solar and Shingle interconnection by Foti, Marina, Galiazzo, Marco, Sovernigo, Enrico, Frasson, Nicola, Gerardi, Cosimo, Guglielmino, Alfredo, Litrico, Grazia, Sciuto, Marcello, Spampinato, Antonio, Ragonesi, Antonino, Rametta, Francesco, Canino, Andrea, Carbonaro, Agata, Coco, Fabrizio, Di Stefano, Agnese, Bizzarri, Fabrizio

“…Efficiency remains the key index among manufacturers' advancements towards an increased module power output. Silicon heterojunction (SHJ) and shingling…”
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High Efficiency Silicon Heterojunction Metal Wrap Through Produced in Industrial Pilot Line by Foti, Marina, Guillevin, Nicolas, Kossen, Eric, Okel, Lars, Hoek, Eelko, Carr, Anna, van Aken, Bas, Manshanden, Petra, Rametta, Francesco, Sciuto, Marcello, Spampinato, Antonio, Di Matteo, Alfredo, Ragonesi, Antonino, Coletti, Gianluca, Gerardi, Cosimo

“…In this work, we describe the development of metal wrap through (MWT) silicon heterojunction (SHJ) solar cells and modules using an industrial pilot line. We…”
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Silicon Heterojunction Solar Module using Shingle interconnection by Foti, Marina, Galiazzo, Marco, Cerasti, Lorenzo, Sovernigo, Enrico, Gerardi, Cosimo, Guglielmino, Alfredo, Litrico, Grazia, Sciuto, Marcello, Spampinato, Antonio, Ragonesi, Antonino, Rametta, Francesco, Canino, Andrea, Carbonaro, Agata, Coco, Fabrizio, Di Stefano, Agnese, Bizzarri, Fabrizio

“…Efficiency remains the key index among manufacturers' advancements towards an increased module power output. Silicon heterojunction (SHJ) and shingling…”
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