Search Results - "Spallanzani, Raúl G."
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Complexity of Complement Resistance Factors Expressed by Acinetobacter baumannii Needed for Survival in Human Serum
Published in The Journal of immunology (1950) (15-10-2017)“…is a bacterial pathogen with increasing impact in healthcare settings, due in part to this organism's resistance to many antimicrobial agents, with pneumonia…”
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Predictive Outcomes for HER2-enriched Cancer Using Growth and Metastasis Signatures Driven By SPARC
Published in Molecular cancer research (01-03-2017)“…Understanding the mechanism of metastatic dissemination is crucial for the rational design of novel therapeutics. The secreted protein acidic and rich in…”
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IL‐27 stimulates human NK‐cell effector functions and primes NK cells for IL‐18 responsiveness
Published in European journal of immunology (01-01-2015)“…IL‐27, a member of the IL‐12 family of cytokines, is produced by APCs, and displays pro‐ and anti‐inflammatory effects. How IL‐27 affects human NK cells still…”
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Histone deacetylase inhibitors impair NK cell viability and effector functions through inhibition of activation and receptor expression
Published in Journal of leukocyte biology (01-02-2012)“…Histone deacetylase inhibitors (HDACi) severely impair NK cell‐mediated functions, which has translational consequences as HDACi could weaken immune…”
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Regulatory Dendritic Cells Restrain NK Cell IFN-γ Production through Mechanisms Involving NKp46, IL-10, and MHC Class I-Specific Inhibitory Receptors
Published in The Journal of immunology (1950) (01-09-2015)“…Cross-talk between mature dendritic cells (mDC) and NK cells through the cell surface receptors NKp30 and DNAM-1 leads to their reciprocal activation. However,…”
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Low doses of CPS49 and flavopiridol combination as potential treatment for advanced prostate cancer
Published in Current pharmaceutical biotechnology (01-01-2015)“…Prostate cancer (PCa) still ranks as the second most frequently diagnosed cancer and metastatic castration resistant prostate cancer (CRPC) is a foremost cause…”
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Regulatory T cells play a crucial role in maintaining sperm tolerance and male fertility
Published in Proceedings of the National Academy of Sciences - PNAS (12-09-2023)“…Regulatory T cells (Tregs) modulate tissue homeostatic processes and immune responses. Understanding tissue-Treg biology will contribute to developing…”
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NK Cells Restrain Spontaneous Antitumor CD8+ T Cell Priming through PD-1/PD-L1 Interactions with Dendritic Cells
Published in The Journal of immunology (1950) (01-08-2016)“…Despite the classical function of NK cells in the elimination of tumor and of virus-infected cells, evidence for a regulatory role for NK cells has been…”
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Abstract 4140: Secreted protein acidic and rich in cysteine (SPARC) promotes mammary tumor growth and dissemination through immune and non-immune mediated mechanisms
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…Abstract Secreted protein and rich in cysteine (SPARC) is a matricellular glycoprotein which has been extensively associated with breast cancer progression,…”
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