Search Results - "Spaich, Sebastian"

Atherosclerosis is aggravated by iron overload and ameliorated by dietary and pharmacological iron restriction by Vinchi, Francesca, Porto, Graca, Simmelbauer, Andreas, Altamura, Sandro, Passos, Sara T, Garbowski, Maciej, Silva, André M N, Spaich, Sebastian, Seide, Svenja E, Sparla, Richard, Hentze, Matthias W, Muckenthaler, Martina U

“…Abstract Aims Whether and how iron affects the progression of atherosclerosis remains highly debated. Here, we investigate susceptibility to atherosclerosis in…”
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Relationship between markers of inflammation and hemodynamic stress and death in patients with out-of-hospital cardiac arrest by Zelniker, Thomas A., Kaya, Ziya, Gamerdinger, Eva, Spaich, Sebastian, Stiepak, Jan, Giannitsis, Evangelos, Katus, Hugo A., Preusch, Michael R.

“…Biomarkers that reflect hemodynamic stress, inflammation, extracellular matrix remodeling, angiogenesis, and endothelial dysfunction may improve risk…”
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Feasibility of CardioSecur®, a Mobile 4-Electrode/22-Lead ECG Device, in the Prehospital Emergency Setting by Spaich, Sebastian, Kern, Hanna, Zelniker, Thomas A, Stiepak, Jan, Gabel, Michael, Popp, Erik, Katus, Hugo A, Preusch, Michael R

“…This study explores the application of CardioSecur® (CS-ECG), a hand-held 4-electrode/22-lead ECG-device, in comparison with conventional 12-lead…”
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Novel biomarkers for risk stratification in pulmonary arterial hypertension by Zelniker, Thomas, Uhlmann, Lorenz, Spaich, Sebastian, Friedrich, Jörg, Preusch, Michael R, Meyer, Franz J, Katus, Hugo A, Giannitsis, Evangelos

“…Risk stratification in pulmonary arterial hypertension (PAH) is paramount to identifying individuals at highest risk of death. So far, there are only limited…”
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Abstract 14870: Adrenomedullin in Patients With Out-of-Hospital Cardiac Arrest by Zelniker, Thomas A, Schwall, Dominik, Hamidi, Fardin, Steinbach, Simone, Scheller, Pascal, Spaich, Sebastian, Giannitsis, Evangelos, Katus, Hugo A, Frey, Norbert, Preusch, Michael R

“…IntroductionAdrenomedullin (ADM) is a free circulating peptide that regulates endothelial barrier function and vascular tone. Here, we sought to study the…”
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Forebrain corticosteroid receptors promote post-myocardial infarction depression and mortality by Bruns, Bastian, Daub, Ricarda, Schmitz, Thomas, Hamze-Sinno, Maria, Spaich, Sebastian, Dewenter, Matthias, Schwale, Chrysovalandis, Gass, Peter, Vogt, Miriam, Katus, Hugo, Herzog, Wolfgang, Friederich, Hans-Christoph, Frey, Norbert, Schultz, Jobst-Hendrik, Backs, Johannes

“…Myocardial infarction (MI) with subsequent depression is associated with increased cardiac mortality. Impaired central mineralocorticoid (MR) and…”
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Clinical and procedural characteristics of patients with acute coronary syndrome during the COVID-19 pandemic 2020 compared to a control group from 2019 by Ong, Peter, Schäfer, Stefanie, Karagülle-Dörrenhaus, Louisa, Rau, Clara, Fröbel, Sarah, Spaich, Sebastian, Bekeredjian, Raffi

“…During the COVID-19 pandemic medical treatments including emergencies were often delayed, in part because of fear of an infection with Sars-CoV-2. Even…”
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First real-world experience with CardioSecur® in the preclinical setting – When time does matter by Kern, Hanna, Stiepak, Jan, Popp, Erik, Spaich, Sebastian, Zelniker, Thomas, Giannitsis, Evangelos, Katus, Hugo, Preusch, Michael

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First real-world experience with CardioSecur® in the preclinical setting – When time does matter by Kern, Hanna, Stiepak, Jan, Popp, Erik, Spaich, Sebastian, Zelniker, Thomas, Giannitsis, Evangelos, Katus, Hugo, Preusch, Michael

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Low-Iron Diet and Chelation Therapy Rescue Severe Atherosclerosis Associated with High Circulating Iron Levels by Vinchi, Francesca, Simmelbauer, Andreas, Altamura, Sandro, Spaich, Sebastian, Sparla, Richard, Galy, Bruno, Hentze, Matthias W., Muckenthaler, Martina U.

“…In 1981 Sullivan proposed the "iron hypothesis", which states that iron is detrimental for the cardiovascular system, promoting atherosclerosis progression…”
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F-Box and Leucine-Rich Repeat Protein 22 Is a Cardiac-Enriched F-Box Protein That Regulates Sarcomeric Protein Turnover and Is Essential for Maintenance of Contractile Function In Vivo by Spaich, Sebastian, Will, Rainer D, Just, Steffen, Spaich, Saskia, Kuhn, Christian, Frank, Derk, Berger, Ina M, Wiemann, Stefan, Korn, Bernhard, Koegl, Manfred, Backs, Johannes, Katus, Hugo A, Rottbauer, Wolfgang, Frey, Norbert

“…RATIONALE:The emerging role of the ubiquitin–proteasome system in cardiomyocyte function and homeostasis implies the necessity of tight regulation of protein…”
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Mid-regional pro-adrenomedullin and lactate levels for risk stratification in patients with out-of-hospital cardiac arrest by Zelniker, Thomas A, Schwall, Dominik, Hamidi, Fardin, Steinbach, Simone, Scheller, Pascal, Spaich, Sebastian, Michels, Guido, Giannitsis, Evangelos, Katus, Hugo A, Frey, Norbert, Preusch, Michael R

“…Abstract Aims Adrenomedullin (ADM) is a free-circulating peptide that regulates endothelial barrier function and vascular tone. Here, we sought to study the…”
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Serum neprilysin and the risk of death in patients with out-of-hospital cardiac arrest of non-traumatic origin by Zelniker, Thomas A, Spaich, Sebastian, Stiepak, Jan, Steger, Florian, Katus, Hugo A, Preusch, Michael R

“…Background: Early risk stratification remains an unmet clinical need in patients with in out-of-hospital cardiac arrest. We hypothesised that soluble…”
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Fibroblast growth factor 23 (FGF-23) is an early predictor of mortality in patients with cardiac arrest by Spaich, Sebastian, Zelniker, Thomas, Endres, Philipp, Stiepak, Jan, Uhlmann, Lorenz, Bekeredjian, Raffi, Chorianopoulos, Emmanuel, Giannitsis, Evangelos, Backs, Johannes, Katus, Hugo A, Preusch, Michael R

“…Abstract Background Post-cardiac arrest management has seen significant advances with profound improvements in survival and neurologic outcome. However, early…”
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Ongoing controversies surrounding cardiac remodeling: is it black and white-or rather fifty shades of gray? by Spaich, Sebastian, Katus, Hugo A, Backs, Johannes

“…Cardiac remodeling describes the heart's multimodal response to a myriad of external or intrinsic stimuli and stressors most of which are probably only…”
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