Search Results - "Spahr, C S"

Mass spectrometric identification of proteins released from mitochondria undergoing permeability transition by Patterson, S D, Spahr, C S, Daugas, E, Susin, S A, Irinopoulou, T, Koehler, C, Kroemer, G

“…Mitochondrial membrane permeabilization is a rate-limiting step of cell death. This process is, at least in part, mediated by opening of the permeability…”
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Purification and biochemical characterization of interchromatin granule clusters by Mintz, Paul J, Patterson, Scott D, Neuwald, Andrew F, Spahr, Chris S, Spector, David L

“…Components of the pre‐mRNA splicing machinery are localized in interchromatin granule clusters (IGCs) and perichromatin fibrils (PFs). Here we report the…”
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Optimization of capillary chromatography ion trap-mass spectrometry for identification of gel-separated proteins by Courchesne, P L, Jones, M D, Robinson, J H, Spahr, C S, McCracken, S, Bentley, D L, Luethy, R, Patterson, S D

“…The current paradigm for protein identification using mass spectrometric derived peptide-mass and fragment-ion data employs computer algorithms which match…”
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Heparin Is Essential for a Single Keratinocyte Growth Factor Molecule To Bind and Form a Complex with Two Molecules of the Extracellular Domain of Its Receptor by Hsu, Yueh-Rong, Nybo, Rebecca, Sullivan, John K, Costigan, Victoria, Spahr, Christopher S, Wong, Caroline, Jones, Michael, Pentzer, Andrea G, Crouse, Jill A, Pacifici, Robert E, Lu, Hsieng S, Morris, Charles F, Philo, John S

“…Keratinocyte growth factor (KGF or FGF-7) is a member of the heparin binding fibroblast growth factor (FGF) family and is a paracrine mediator of proliferation…”
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Identification of incompletely processed potential Carboxypeptidase E substrates from CpEfat/CpEfat mice by Bures, Edward J., Courchesne, Paul L., Douglass, James, Chen, Kui, Davis, Michael T., Jones, Michael D., McGinley, Michael D., Robinson, John H., Spahr, Chris S., Sun, Jilin, Wahl, Robert C., Patterson, Scott D.

“…In an attempt to identify peptides that may be involved in the obese phenotype observed in CpEfat/CpEfat mice (deficient in Carboxypeptidase E, CpE) samples…”
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A simplified device for protein identification by microcapillary gradient liquid chromatography-tandem mass spectrometry by McGinley, Michael D., Davis, Michael T., Robinson, John H., Spahr, Chris S., Bures, Edward J., Beierle, Jill, Mort, Jessica, Patterson, Scott D.

“…A simplified device and procedure have been developed for microcapillary gradient liquid chromatography‐tandem mass spectrometry (LC‐MS/MS). This procedure has…”
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Towards defining the urinary proteome using liquid chromatography-tandem mass spectrometry. I. Profiling an unfractionated tryptic digest by Spahr, C S, Davis, M T, McGinley, M D, Robinson, J H, Bures, E J, Beierle, J, Mort, J, Courchesne, P L, Chen, K, Wahl, R C, Yu, W, Luethy, R, Patterson, S D

“…The proteome of normal male urine from a commercial pooled source has been examined using direct liquid chromatography-tandem mass spectrometry (LC-MS/MS). The…”
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Towards defining the urinary proteome using liquid chromatography-tandem mass spectrometry. II. Limitations of complex mixture analyses by Davis, M T, Spahr, C S, McGinley, M D, Robinson, J H, Bures, E J, Beierle, J, Mort, J, Yu, W, Luethy, R, Patterson, S D

“…With an emphasis on obtaining a multitude of high quality tandem mass spectrometry spectra for protein identification, instrumental parameters are described…”
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Automated LC–LC–MS–MS platform using binary ion-exchange and gradient reversed-phase chromatography for improved proteomic analyses by Davis, Michael T., Beierle, Jill, Bures, Edward T., McGinley, Michael D., Mort, Jessica, Robinson, John H., Spahr, Chris S., Yu, Wen, Luethy, Roland, Patterson, Scott D.

“…A simple multidimensional liquid chromatography system utilizing an isocratic pump and a HPLC system is described for the comprehensive proteomic analysis of…”
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Proteomic analysis of interchromatin granule clusters by Saitoh, Noriko, Spahr, Chris S, Patterson, Scott D, Bubulya, Paula, Neuwald, Andrew F, Spector, David L

“…A variety of proteins involved in gene expression have been localized within mammalian cell nuclei in a speckled distribution that predominantly corresponds to…”
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Simplification of complex peptide mixtures for proteomic analysis: Reversible biotinylation of cysteinyl peptides by Spahr, Chris S., Susin, Santos A., Bures, Edward J., Robinson, John H., Davis, Michael T., McGinley, Michael D., Kroemer, Guido, Patterson, Scott D.

“…A rapid means of identifying many components in an enriched mixture of proteins is enzymatic digestion of the entire protein fraction. This complex peptide…”
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Identification of incompletely processed potential Carboxypeptidase E substrates from CpE super(fat)/CpE super(fat) mice by Bures, E J, Courchesne, P L, Douglass, J, Chen, K, Davis, M T, Jones, MD, McGinley, MD, Robinson, J H, Spahr, C S, Sun, J, Wahl, R C, Patterson, S D

“…In an attempt to identify peptides that may be involved in the obese phenotype observed in CpE super(fat)/CpE super(fat) mice (deficient in Carboxypeptidase E,…”
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