Search Results - "Spahn, E."

Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV by Sheahan, Timothy P., Sims, Amy C., Leist, Sarah R., Schäfer, Alexandra, Won, John, Brown, Ariane J., Montgomery, Stephanie A., Hogg, Alison, Babusis, Darius, Clarke, Michael O., Spahn, Jamie E., Bauer, Laura, Sellers, Scott, Porter, Danielle, Feng, Joy Y., Cihlar, Tomas, Jordan, Robert, Denison, Mark R., Baric, Ralph S.

“…Middle East respiratory syndrome coronavirus (MERS-CoV) is the causative agent of a severe respiratory disease associated with more than 2468 human infections…”
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Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses by Sheahan, Timothy P, Sims, Amy C, Graham, Rachel L, Menachery, Vineet D, Gralinski, Lisa E, Case, James B, Leist, Sarah R, Pyrc, Krzysztof, Feng, Joy Y, Trantcheva, Iva, Bannister, Roy, Park, Yeojin, Babusis, Darius, Clarke, Michael O, Mackman, Richard L, Spahn, Jamie E, Palmiotti, Christopher A, Siegel, Dustin, Ray, Adrian S, Cihlar, Tomas, Jordan, Robert, Denison, Mark R, Baric, Ralph S

“…Emerging viral infections are difficult to control because heterogeneous members periodically cycle in and out of humans and zoonotic hosts, complicating the…”
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Mixing of dry powders for inhalation: A review by Spahn, Jamie E., Zhang, Feng, Smyth, Hugh D.C.

“…[Display omitted] The process of solids mixing is applied across a considerable range of industries. Pharmaceutical science is one of those industries that…”
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Feasibility of a High-Dose Inhaled Indomethacin Dry Powder with Dual Deposition for Pulmonary and Oral Delivery by Spahn, Jamie E, Hefnawy, Amr, Zhang, Feng, Smyth, Hugh D C

“…In this study we have developed a high-dose dry powder inhaler formulation of indomethacin using a novel approach to carrier-based formulations. Specifically,…”
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Refurbishment of a 30-MJ-Pulsed Power Supply for Pulsed Power Applications by Liebfried, O., Brommer, V., Scharnholz, S., Spahn, E.

“…The French-German Research Institute of Saint-Louis obtained essential parts of a 30-MJ energy supply formerly installed at Rheinmetall in Unterlüß, Germany…”
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Compact High Voltage IGBT Switch for Pulsed Power Applications by Zorngiebel, V., Spahn, E., Buderer, G., Welleman, A., Fleischmann, W.

“…This paper describes the development of a semiconductor based switch for use in pulsed power technology. Because of the more stable operating conditions, given…”
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50-kJ Ultracompact Pulsed-Power Supply Unit for Active Protection Launcher Systems by Spahn, E., Sterzelmeier, K., Gauthier-Blum, C., Brommer, V., Sinniger, L., Grasser, B.

“…The impulsive acceleration of active protection elements such as armor plates or other terminal ballistics interception devices can preferably be realized by…”
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Pre-plasticization of thermal binder facilitates processing and granule growth during melt granulation of gabapentin using co-rotating twin screw extruder by Spahn, Jamie E., Zhang, Feng

“…Plasticization, a common method of reducing the polymer melt viscosity in plastics extrusion, was investigated to improve the processability of a…”
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Critical research gaps in electronic cigarette devices and nicotine aerosols by Spahn, Jamie E., Stavchansky, Salomon A., Cui, Zhengrong

“…[Display omitted] Electronic cigarettes (e-cigs) are devices that aerosolize nicotine-containing liquids for delivery as an inhaled vapor. E-cigs are currently…”
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Development of a novel method for the continuous blending of carrier-based dry powders for inhalation using a co-rotating twin-screw extruder by Spahn, Jamie E., Hefnawy, Amr, Smyth, Hugh D.C., Zhang, Feng

“…[Display omitted] Twin-screw extruders are useful in tuning certain product characteristics due to the ability to greatly modify screw profiles as well as…”
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The staying power of adhesion-associated antioxidant activity in Mytilus californianus by Miller, Dusty R., Spahn, Jamie E., Waite, J. Herbert

“…The California mussel, Mytilus californianus, adheres in the highly oxidizing intertidal zone with a fibrous holdfast called the byssus using 3,…”
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Twin-Screw Continuous Mixing Can Produce Dry Powder Inhalation Mixtures for Pulmonary Delivery by Ren, Angela, Koleng, 3rd, John J, Costello, Mark, Spahn, Jamie E, Smyth, Hugh D C, Zhang, Feng

“…The feasibility of twin-screw corotating extruder as a continuous process mixer to prepare dry powder inhalation (DPI) powders was investigated. Interactive…”
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Redox Capacity of an Extracellular Matrix Protein Associated with Adhesion in Mytilus californianus by Nicklisch, Sascha C. T, Spahn, Jamie E, Zhou, Hongjun, Gruian, Cristina M, Waite, J. Herbert

“…Adhesive mussel foot proteins (Mfps) rely in part on DOPA (3,4-dihydroxyphenyl-l-alanine) side chains to mediate attachment to mineral surfaces underwater…”
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A Model for Predicting Transition in Railgun Fiber Brush Armatures by Reck, B., Lehmann, P., Spahn, E., Wenning, W., Vo, M.D.

“…The PEGASUS railgun at the French-German Research Institute of Saint-Louis is capable of launching 0.3-kg projectiles with muzzle velocities greater than 2500…”
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High-power MOSFETs and fast-switching thyristors utilized as opening switches for inductive storage systems by Scharnholz, S., Brommer, V., Buderer, G., Spahn, E.

“…Taking aim at the utilization of inductive storage systems with their manifold advantages for pulsed power applications (e.g., higher energy density, lower…”
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A compact pulse forming network, based on semiconducting switches, for electric gun applications by Spahn, E., Buderer, G., Wenning, W.

“…At ISL a highly modular pulse forming network (PFN) for electric guns (railguns, electrothermal-chemical guns) has been developed and built up. The PFN…”
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Edge termination strategies for a 4 kV 4H-SiC thyristor by BROSSELARD, P, PLANSON, D, SCHARNHOLZ, S, RAYNAUD, C, ZORNGIEBEL, V, LAZAR, M, CHANTE, J.-P, SPAHN, E

“…Thyristors able to block 4 kV have been fabricated and characterised. The experimental forward current is 1.3 A @ V-AK = 10 V for a 9 mA gate current during…”
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Intrathecal Morphine for Analgesia After Postpartum Bilateral Tubal Ligation by Habib, Ashraf S., Muir, Holly A., White, William D., Spahn, Tede E., Olufolabi, Adeyemi J., Breen, Terrance W.

“…Postpartum bilateral tubal ligation (PPBTL) causes postoperative pain. We designed this study to determine the efficacy of 50 μg intrathecal morphine for…”
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Novel PFN with current turn-off capability for electric launchers by Spahn, E., Buderer, G., Gauthier-Blum, C.

“…In the last years at ISL a lot of work has been performed in order to develop and install highly flexible pulse forming networks (PFN), based on capacitors as…”
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Railgun modeling with the P-Spice code by Wey, J., Spahn, E., Lichtenberger, M.

“…Starting from the conventional modeling of the railgun as an electrical circuit coupled to a mechanical system, we have developed our own model including…”
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