Search Results - "Spagnoli, Mariangela"
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Precision Medicine: Determination of Ribavirin Urinary Metabolites in Relation to Drug Adverse Effects in HCV Patients
Published in International journal of molecular sciences (01-09-2022)“…The most commonly used antiviral treatment against hepatitis C virus is a combination of direct-acting antivirals (DAAs) and ribavirin (RBV), which leads to a…”
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Metabolic Biomarkers of Red Beetroot Juice Intake at Rest and after Physical Exercise
Published in Nutrients (22-04-2023)“…Red beetroot is known to be a health-promoting food. However, little attention is placed on intestinal bioactive compound absorption. The aim of the study was…”
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NMR-based metabolomics for investigating urinary profiles of metal carpentry workers exposed to welding fumes and volatile organic compounds
Published in Frontiers in public health (07-08-2024)“…Metal carpentry includes a wide range of work activities such as welding and cutting metallic components, use of solvents and paints. Therefore, the employees…”
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Oxidative stress in occupational exposure to styrene vapors and dangerous chemicals in the shipbuilding industry
Published in Frontiers in toxicology (2023)“…In the shipbuilding industry, workers are exposed to a variety of dangerous chemicals, styrene being one of them. The International Agency for Research on…”
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NMR Untargeted and HPLC-MS/MS Targeted Metabolomic Approaches for Evaluating Styrene Exposure in the Urine of Shipyard Workers
Published in Toxics (Basel) (28-02-2024)“…Due to its chemical properties, styrene is largely employed in the manufacturing of several products including rubber, polymers and resins, and it is…”
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Biomonitoring of Exposure to Urban Pollutants and Oxidative Stress during the COVID-19 Lockdown in Rome Residents
Published in Toxics (Basel) (21-05-2022)“…The objective of this study is to evaluate the effects of traffic on human health comparing biomonitoring data measured during the COVID-19 lockdown, when…”
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P-367 NMR-BASED METABOLOMICS: NOVEL APPLICATION IN EXPOSOMICS
Published in Occupational medicine (Oxford) (05-07-2024)“…Abstract Introduction Metabolomics studies the end products of biological processes ocurring in living systems, based on the quantification of low molecular…”
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Landfill fire impact on bee health: beneficial effect of dietary supplementation with medicinal plants and probiotics in reducing oxidative stress and metal accumulation
Published in Environmental science and pollution research international (30-12-2023)“…The honey bee is an important pollinator insect susceptible to environmental contaminants. We investigated the effects of a waste fire event on elemental…”
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Targeted and untargeted metabolomics applied to occupational exposure to hyperbaric atmosphere
Published in Toxicology letters (01-08-2020)“…•Six divers were monitored during two experiments of exposure to hyperbaric atmosphere in dry and wet conditions•30 minutes at 3 atmospheres increased the…”
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Hyperbaric Exposure of Scuba Divers Affects the Urinary Excretion of Nucleic Acid Oxidation Products and Hypoxanthine
Published in International journal of environmental research and public health (04-03-2022)“…In recent studies, oxidative stress after scuba diving has been explored by measuring urinary biomarkers in volunteers under controlled conditions. Dive depth…”
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NMR-based metabolic study of leaves of three species of Actinidia with different degrees of susceptibility to Pseudomonas syringae pv. actinidiae
Published in Natural product research (17-07-2020)“…Bacterial canker of Actinidia, caused by the bacterium Pseudomonas syringae pv. actinidiae (Psa), is the most serious disease of these plants worldwide. Leaves…”
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Non-aqueous reversed-phase liquid-chromatography of tocopherols and tocotrienols and their mass spectrometric quantification in pecan nuts
Published in Journal of food composition and analysis (01-12-2017)“…•A HPLC–MS method was developed for the characterization of vitamin E homologues.•Eight tocols were separated on a C30 column (15°C) under isocratic…”
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Comparison of the metabolic profile of pecan nuts cultivars [ Carya illinoinensis (Wangenh.) K. Koch] by NMR spectroscopy
Published in Natural product research (30-10-2023)“…Pecan nuts (Carya illinoinensis (Wangenh.) K. Koch) contain the highest number of phytochemicals of all nuts, are a natural source of unsaturated fatty acids…”
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18 Effects of Rome Lockdown During COVID-19 Pandemic on Urinary Exposure Biomarkers of Urban Pollutants
Published in Annals of work exposures and health (10-05-2023)“…Abstract The 2020 lockdown represented a natural experiment to measure the effects of traffic pollution on human health, due to the restrictions during the…”
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Monitoring of pistachio (Pistacia Vera) ripening by high field nuclear magnetic resonance spectroscopy
Published in Natural product research (03-04-2017)“…The metabolic profiling of pistachio (Pistacia vera) aqueous extracts from two different cultivars, namely 'Bianca' and 'Gloria', was monitored over the months…”
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NMR-based metabolic study of leaves of three species of Actinidia with different degrees of susceptibility to Pseudomonas syringae pv. actinidiae
Published in Natural product research (27-02-2019)“…Bacterial canker of Actinidia, caused by the bacterium Pseudomonas syringae pv. actinidiae (Psa), is the most serious disease of these plants worldwide. Leaves…”
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Occupational exposure to antineoplastic agents induces a high level of chromosome damage. Lack of an effect of GST polymorphisms
Published in Toxicology and applied pharmacology (15-08-2007)“…The aim of our study was to investigate whether occupational exposure to antineoplastic drugs (AND) resulted in genetic damage, possibly indicative of adverse…”
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Trace determination of anthracyclines in urine: a new high-performance liquid chromatography/tandem mass spectrometry method for assessing exposure of hospital personnel
Published in Rapid communications in mass spectrometry (01-01-2004)“…Health‐care workers handling antineoplastic agents may be exposed to extremely low doses of these drugs. Very sensitive and specific analytical methods are…”
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A Novel Synthetic Route to Sapphyrins
Published in Journal of organic chemistry (25-07-1997)“…New methodology has been developed for the synthesis of so-called sapphyrins, pentapyrrolic “expanded porphyrins”. An efficient approach involving…”
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