Search Results - "Spagnoli, G C"

Cancer–testis antigen expression in triple-negative breast cancer by Curigliano, G., Viale, G., Ghioni, M., Jungbluth, A.A., Bagnardi, V., Spagnoli, G.C., Neville, A.M., Nolè, F., Rotmensz, N., Goldhirsch, A.

“…Background: Cancer–testis (CT) antigens, frequently expressed in human germline cells but not in somatic tissues, may become aberrantly reexpressed in…”
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Human bone marrow mesenchymal stem cells and chondrocytes promote and/or suppress the in vitro proliferation of lymphocytes stimulated by interleukins 2, 7 and 15 by Bocelli-Tyndall, C, Bracci, L, Schaeren, S, Feder-Mengus, C, Barbero, A, Tyndall, A, Spagnoli, G C

“…To investigate whether human bone marrow-derived mesenchymal stem cells (BM-MSCs) and articular chondrocytes (ACs) affect the in vitro proliferation of T…”
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Multiple mechanisms underlie defective recognition of melanoma cells cultured in three-dimensional architectures by antigen-specific cytotoxic T lymphocytes by FEDER-MENGUS, C, GHOSH, S, RESCHNER, A, WEBER, W. P, WYLER, S, ZAJAC, P, TERRACCIANO, L, OERTLI, D, HEBERER, M, MARTIN, I, SPAGNOLI, G. C

“…Cancer cells' growth in three-dimensional (3D) architectures promotes resistance to drugs, cytokines, or irradiation. We investigated effects of 3D culture as…”
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Phase I study in melanoma patients of a vaccine with peptide-pulsed dendritic cells generated in vitro from CD34+ hematopoietic progenitor cells by MACKENSEN, A, HERBST, B, CHEN, J.-L, KÖHLER, G, NOPPEN, C, HERR, W, SPAGNOLI, G. C, CERUNDOLO, V, LINDEMANN, A

“…Dendritic cells (DCs) are professional antigen-presenting cells (APCs) that can be used for vaccination purposes, to induce a specific T-cell response in vivo…”
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Expression of MAGE-A Cancer/Testis Antigens in Esophageal Squamous Cell Carcinomas by HAIER, J, OWZCARECK, M, GULLER, U, SPAGNOLI, G. C, BÜRGER, H, SENNINGER, N, KOCHER, Th

“…Background: Although the diagnosis and therapy of esophageal cancer have improved over the past decade, the prognosis remains dismal. Since MAGE-A…”
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Genes Encoding Tumor-Specific Antigens Are Expressed in Human Myeloma Cells by van Baren, Nicolas, Brasseur, Francis, Godelaine, Danièle, Hames, Gérald, Ferrant, Augustin, Lehmann, Frédéric, André, Marc, Ravoet, Christophe, Doyen, Chantal, Spagnoli, Giulio C., Bakkus, Marleen, Thielemans, Kris, Boon, Thierry

“…Genes of the MAGE, BAGE, GAGE, and LAGE-1/NY-ESO-1families encode antigenic peptides that are presented by HLA class I molecules and that are recognized on…”
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NY-ESO-1 tumour associated antigen is a cytoplasmic protein detectable by specific monoclonal antibodies in cell lines and clinical specimens by SCHULTZ-THATER, E, NOPPEN, C, GUDAT, F, DÜRMÜLLER, U, ZAJAC, P, KOCHER, T, HEBERER, M, SPAGNOLI, G. C

“…NY-ESO-1 gene encodes a novel member of the cancer/testis (CT) family of human tumour-associated antigens (TAA). Specific monoclonal antibodies (mAb) have…”
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High density oligonucleotide array analysis of interferon-α2a sensitivity and transcriptional response in melanoma cells by CERTA, U, SEILER, M, PADOVAN, E, SPAGNOLI, G. C

“…Interferon alpha (IFN-α) represents an adjuvant therapy of proven effectiveness in increasing disease-free interval and survival in subgroups of melanoma…”
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Why do infections cause cancer? by Antonelli, G., Spagnoli, G.C.

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MAGE-3 immunoreactivity in formalin-fixed, paraffin-embedded primary and metastatic melanoma: frequency and distribution by Hofbauer, GF, Schaefer, C, Noppen, C, Boni, R, Kamarashev, J, Nestle, FO, Spagnoli, GC, Dummer, R

“…Monoclonal antibody 57B specifically detects MAGE-3 gene protein expression. MAGE-derived peptides are recognized by CD8+ T cells and applied in immunotherapy…”
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Monoclonal antibody 57B stains tumor tissues that express gene MAGE‐A4 by Landry, Claire, Brasseur, Francis, Spagnoli, Giulio C., Marbaix, Etienne, Boon, Thierry, Coulie, Pierre, Godelaine, Danièle

“…Monoclonal antibody (Mab) 57B, which was raised against a recombinant MAGE‐A3 protein, was tested for its ability to stain cells expressing various members of…”
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Involvement of the multilineage CD38 molecule in a unique pathway of cell activation and proliferation by Funaro, A, Spagnoli, GC, Ausiello, CM, Alessio, M, Roggero, S, Delia, D, Zaccolo, M, Malavasi, F

“…We report clear evidence that the interaction of the CD38 molecule with the specific mAb A10 on normal human cells and lines modulates the expression of…”
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Expression of MAGE-1 and -3 genes and gene products in human hepatocellular carcinoma by KARIYAMA, K, HIGASHI, T, FUJIWARA, K, NAKAYAMA, E, TERRACCIANO, L, SPAGNOLI, G. C, TSUJI, T, KOBAYASHI, Y, NOUSO, K, NAKATSUKASA, H, YAMANO, T, ISHIZAKI, M, KANEYOSHI, T, TOSHIKUNI, N, OHNISHI, T

“…MAGE gene family encodes peptides recognized by autologous cytotoxic T lymphocytes in a major histocompatibility complex (MHC) class-I restricted fashion. In…”
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High-level expression of cancer/testis antigen NY-ESO-1 and human granulocyte-macrophage colony-stimulating factor in dendritic cells with a bicistronic retroviral vector by Batchu, R B, Moreno, A M, Szmania, S, Gupta, S K, Zhan, F, Rosen, N, Kozlowski, M, Spencer, T, Spagnoli, G C, Shaughnessy, J, Barlogie, B, Tricot, G, van Rhee, F

“…Tumor-specific genes delivered to dendritic cells (DCs) have been used for the generation of cytotoxic T cells (CTLs), but their application has been limited…”
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Identification and intracellular location of MAGE-3 gene product by KOCHER, T, SCHULTZ-THATER, E, GUDAT, F, SCHAEFER, C, CASORATI, G, JURETIC, A, WILLIMANN, T, HARDER, F, HEBERER, M, SPAGNOLI, G. C

“…The human MAGE-3 gene encodes a melanoma antigenic epitope recognized by specific cytotoxic T lymphocytes, but its gene product has not been identified thus…”
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Expression of MAGE tumour-associated antigens is inversely correlated with tumour differentiation in invasive ductal breast cancers: an immunohistochemical study by KAVALAR, R, SARCEVIC, B, SPAGNOLI, G. C, SEPAROVIC, V, SAMIJA, M, TERRACCIANO, L, HEBERER, M, JURETIC, A

“…MAGE (Melanoma antigen E) family gene products encompass tumour-associated antigens (TAAs) recognised by human leukocyte antigen (HLA)-restricted specific…”
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Cytokine gene expression in human peripheral blood mononuclear cells stimulated by mannoprotein constituents from Candida albicans by AUSIELLO, C. M, URBANI, F, GESSANI, S, SPAGNOLI, G. C, GOMEZ, M. J, CASSONE, A

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Naturally processed and concealed HLA‐A2.1‐restricted epitopes from tumor‐associated antigen tyrosinase‐related protein‐2 by Noppen, Christoph, Lévy, Frédéric, Burri, Lena, Zajac, Paul, Remmel, Eugenia, Schaefer, Christoph, Lüscher, Urs, Heberer, Michael, Spagnoli, Giulio C.

“…In this study, a computer‐assisted reverse immunology approach was utilized in order to identify potentially antigenic peptides derived from the…”
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Phosphorylated CXCR4 expression has a positive prognostic impact in colorectal cancer by Weixler, B., Renetseder, F., Facile, I., Tosti, N., Cremonesi, E., Tampakis, A., Delko, T., Eppenberger-Castori, S., Tzankov, A., Iezzi, G., Kettelhack, C., Soysal, S. D., von Holzen, U., Spagnoli, G. C., Terracciano, L., Tornillo, L., Droeser, Raoul A., Däster, S.

“…Background The CXCL12-CXCR4 chemokine axis plays an important role in cell trafficking as well as in tumor progression. In colorectal cancer (CRC), the…”
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Role of glutamine in the immune response in critical illness by HEBERER, M, BABST, R, JURETIC, A, GROSS, T, HÖRIG, H, HARDER, F, SPAGNOLI, G. C

“…The dependence of human lymphocyte functions on the exogenous provision of glutamine (GLN) was evaluated in a series of in vitro experiments. The transcription…”
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