Search Results - "Spagnoli, Anna"

Wnt signaling in bone, kidney, intestine, and adipose tissue and interorgan interaction in aging by Chen, Di, Xie, Rong, Shu, Bing, Landay, Alan L., Wei, Changli, Reiser, Jochen, Spagnoli, Anna, Torquati, Alfonso, Forsyth, Christopher B., Keshavarzian, Ali, Sumner, D. Rick

“…Over the last two decades, it has become increasingly apparent that Wnt signaling plays a critical role in development and adult tissue homeostasis in multiple…”
Get full text

Regenerative Effects of Transplanted Mesenchymal Stem Cells in Fracture Healing by Granero‐Moltó, Froilán, Weis, Jared A., Miga, Michael I., Landis, Benjamin, Myers, Timothy J., O'Rear, Lynda, Longobardi, Lara, Jansen, E. Duco, Mortlock, Douglas P., Spagnoli, Anna

“…Mesenchymal stem cells (MSC) have a therapeutic potential in patients with fractures to reduce the time of healing and treat nonunions. The use of MSC to treat…”
Get full text

BMP2 Regulation of CXCL12 Cellular, Temporal, and Spatial Expression Is Essential During Fracture Repair by Myers, Timothy J, Longobardi, Lara, Willcockson, Helen, Temple, Joseph D, Tagliafierro, Lidia, Ye, Ping, Li, Tieshi, Esposito, Alessandra, Moats‐Staats, Billie M, Spagnoli, Anna

“…ABSTRACT The cellular and humoral responses that orchestrate fracture healing are still elusive. Here we report that bone morphogenic protein 2…”
Get full text

Tissue engineering a tendon-bone junction with biodegradable braided scaffolds by Ramakrishna, Harshini, Li, Tieshi, He, Ting, Temple, Joseph, King, Martin W, Spagnoli, Anna

“…Tendons play an important role in transferring stress between muscles and bones and in maintaining the stability of joints. Tendon tears are difficult to heal…”
Get full text

Adipogenic differentiation of adipose tissue-derived human mesenchymal stem cells: effect of gastric bypass surgery by Chen, Jie-Gen, Spagnoli, Anna, Torquati, Alfonso

“…Background Adipose tissue dysfunction is an important feature of obesity characterized by enlarged adipocytes and marked changes in secretion of cytokines…”
Get full text

Rates, Risks, and Time to Fracture in Patients Undergoing Laparoscopic Vertical Sleeve Gastrectomy versus Roux-en-Y Gastric Bypass by Khalid, Syed I., Thomson, Kyle B., Becerra, Adan Z., Omotosho, Philip, Spagnoli, Anna, Torquati, Alfonso

“…Objective: To assess the rates, risks, and time to fracture in patients undergoing laparoscopic vertical sleeve gastrectomy (VSG) versus those undergoing…”
Get full text

Necdin–E2F4 interaction provides insulin-sensitizing effect after weight loss induced by gastric bypass surgery by Pamuklar, Zehra N., M.D., Ph.D, Chen, Jiegen, Ph.D, Muehlbauer, Michael, Ph.D, Spagnoli, Anna, M.D, Torquati, Alfonso, M.D., M.S.C.I

“…Abstract Background The insulin-like growth factor-1 (IGF-1) signaling pathway promotes adipocyte differentiation and, therefore, insulin sensitivity by…”
Get full text

Goodpasture Antigen-binding Protein and Its Spliced Variant, Ceramide Transfer Protein, Have Different Functions in the Modulation of Apoptosis during Zebrafish Development by Granero-Moltó, Froilán, Sarmah, Swapnalee, O'Rear, Lynda, Spagnoli, Anna, Abrahamson, Dale, Saus, Juan, Hudson, Billy G., Knapik, Ela W.

“…Human Goodpasture antigen-binding protein (GPBP) is an atypical protein kinase that phosphorylates the Goodpasture auto-antigen, the α3 chain of collagen IV…”
Get full text

RUNX3 inhibits cell proliferation and induces apoptosis by reinstating transforming growth factor beta responsiveness in esophageal adenocarcinoma cells by Torquati, Alfonso, O'Rear, Lynda, Longobardi, Lara, Spagnoli, Anna, Richards, William O., Daniel Beauchamp, R.

“…SEG-1, a Barrett's-derived esophageal adenocarcinoma cell line, is not responsive to transforming growth factor beta (TGF-β) growth effects. We hypothesize…”
Get full text

Role of Prx1-expressing skeletal cells and Prx1-expression in fracture repair by Esposito, Alessandra, Wang, Lai, Li, Tieshi, Miranda, Mariana, Spagnoli, Anna

“…The healing capacity of bones after fracture implies the existence of adult regenerative cells. However, information on identification and functional role of…”
Get full text

PL-123 Insulin-sensitizing effects of gastric bypass surgery (GBS) are mediated through the necdin-E2F4 interaction by Pamuklar, Zehra, MD, PhD, Chen, Jiegen, MD, PhD, Spagnoli, Anna, MD, Torquati, Alfonso, MD, MSCI

Get full text

Identification of STAT-1 as a Molecular Target of IGFBP-3 in the Process of Chondrogenesis by Spagnoli, Anna, Torello, Monica, Nagalla, Srivinasa R., Horton, William A., Pattee, Patrick, Hwa, Vivian, Chiarelli, Francesco, Roberts, Charles T., Rosenfeld, Ron G.

“…The chondrogenesis process requires the ordered proliferation and differentiation of chondrocytes. Insulin-like growth factor-binding protein (IGFBP)-3, well…”
Get full text

Roux-en-Y gastric bypass decreases serum inflammatory markers and cardiovascular risk factors in obese diabetics by Rossi, Isolina, Omotosho, Philip, Poirier, Jennifer, Spagnoli, Anna, Torquati, Alfonso

“…Obesity and type 2 diabetes mellitus are associated with elevated levels of inflammatory markers. This chronic inflammation is known to contribute to increased…”
Get full text

49 by Torquati, Alfonso, MD, MSCI, Richards, William, MD, Kaiser, Joan, RN, MA, Kernodle, Sherry, RD, Spagnoli, Anna, MD

Get full text

CXCR4 mediates the effects of IGF-1R signaling in rodent bone homeostasis and fracture repair by Esposito, Alessandra, Klüppel, Michael, Wilson, Brittany M., Meka, Sai R.K., Spagnoli, Anna

“…Non-union fractures have considerable clinical and economic burdens and yet the underlying pathogenesis remains largely undetermined. The fracture healing…”
Get full text

Perioperative changes in prouroguanylin hormone response in severely obese subjects after bariatric surgery by Torquati, Alfonso, Shantavasinkul, Prapimporn Chattranukulchai, Omotosho, Philip, Corsino, Leonor, Spagnoli, Anna

“…Prouroguanylin is a gut hormone converted into uroguanylin in the hypothalamus. Uroguanylin induces satiety through guanylyl-cyclase-2C receptor signaling…”
Get full text

A randomised placebo-controlled clinical trial on the efficacy of local lidocaine injections and oral citalopram for the treatment of complex regional pain syndrome by Fallico, Nefer, Padmanabhan, Rahul, Rahman, Shakeel, Somma, Francesco, Spagnoli, Anna Maria

“…Complex regional pain syndrome (CRPS) is a neuropathic pain condition with no universally recognised treatment. The study evaluates the efficacy of a…”
Get full text

Effects of Roux-en-Y Gastric Bypass on Osteoclast Activity and Bone Density in Morbidly Obese Patients with Type 2 Diabetes by Tangalakis, Laurel L, Tabone, Lawrence, Spagnoli, Anna, Muehlbauer, Mike, Omotosho, Philip, Torquati, Alfonso

“…Introduction Roux-en-Y gastric bypass (RYGB) is a well-established treatment for morbid obesity and type 2 diabetes. The effects of RYGB on bone metabolism and…”
Get full text

Association of Bariatric Surgery With Risk of Fracture in Patients With Severe Obesity by Khalid, Syed I., Omotosho, Philip A., Spagnoli, Anna, Torquati, Alfonso

“…Importance Given the complex relationship between body mass index, body composition, and bone density and the correlative nature of the studies that have…”
Get full text

Role of mesenchymal stem cells in regenerative medicine: application to bone and cartilage repair by Granero-Molto, Froilan, Weis, Jared A, Longobardi, Lara, Spagnoli, Anna

“…Mesenchymal stem cells (MSC) are multipotent cells with the ability to differentiate into mesenchyme-derived cells including osteoblasts and chondrocytes. To…”
Get more information