Search Results - "Spaargaren, Michael"
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NH-1,2,3-Triazole Inhibitors of the VIM-2 Metallo-β-Lactamase
Published in ACS medicinal chemistry letters (08-07-2010)“…Metallo-β-lactamases (MBLs) are an emerging cause of bacterial resistance to antibiotic treatment. The VIM-2 β-lactamase is the most commonly encountered MBLs…”
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Inhibitors of VIM-2 by screening pharmacologically active and click-chemistry compound libraries
Published in Bioorganic & medicinal chemistry (15-07-2009)“…VIM-2 is an Ambler class B metallo-β-lactamase (MBL) capable of hydrolyzing a broad-spectrum of β-lactam antibiotics. Although the discovery and development of…”
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Inhibitors of VIM-2 by Screening Pharmacogically Active and Click-Chemistry Compound Libraries
Published in Bioorganic & medicinal chemistry (22-06-2009)“…VIM-2 is an Ambler class B metallo-β-lactamase (MBL) capable of hydrolyzing a broad-spectrum of β-lactam antibiotics. Although the discovery and development of…”
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Journal Article -
4
NH-1,2,3-Triazole-based Inhibitors of the VIM-2 Metallo-β-Lactamase: Synthesis and Structure-Activity Studies
Published in ACS medicinal chemistry letters (08-07-2010)“…Metallo-ß-lactamases (MBL) are an emerging cause of bacterial resistance to antibiotic treatment. The VIM-2 ß-lactamase is the most commonly encountered MBL in…”
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Journal Article Web Resource