Search Results - "Spaan, W.J.M"

O.2.6 A mass spectrometry-based method to detect antiviral drug resistance in human cytomegalovirus by Posthuma, C.C, van der Beek, M.T, Blij-de Brouwer, C.S, Spaan, W.J.M, Kroes, A.C.M, Snijder, E.J

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Internal entry of ribosomes is directed by the 5' noncoding region of classical swine fever virus and is dependent on the presence of an RNA pseudoknot upstream of the initiation codon by Rijnbrand, R, van der Straaten, T, van Rijn, P A, Spaan, W J, Bredenbeek, P J

“…Bicistronic RNAs containing the 373-nucleotide-long 5' nontranslated region (NTR) of the classical swine fever virus (CSFV) genome as intercistronic spacer…”
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Evidence for a coiled-coil structure in the spike proteins of coronaviruses by de Groot, R J, Luytjes, W, Horzinek, M C, van der Zeijst, B A, Spaan, W J, Lenstra, J A

“…The amino acid sequences of the spike proteins from three distantly related coronaviruses have been deduced from cDNA sequences. In the C-terminal half, an…”
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A recombinant Yellow Fever 17D vaccine expressing Lassa virus glycoproteins by Bredenbeek, Peter J., Molenkamp, Richard, Spaan, Willy J.M., Deubel, Vincent, Marianneau, Phillippe, Salvato, Maria S., Moshkoff, Dmitry, Zapata, Juan, Tikhonov, Ilia, Patterson, Jean, Carrion, Ricardo, Ticer, Anysha, Brasky, Kathleen, Lukashevich, Igor S.

“…The Yellow Fever Vaccine 17D (YFV17D) has been used as a vector for the Lassa virus glycoprotein precursor (LASV-GPC) resulting in construction of…”
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The influence of downstream protein-coding sequence on internal ribosome entry on hepatitis C virus and other flavivirus RNAs by RIJNBRAND, R., BREDENBEEK, P.J., HAASNOOT, P.C., KIEFT, J.S., SPAAN, W.J.M., LEMON, S.M.

“…Some studies suggest that the hepatitis C virus (HCV) internal ribosome entry site (IRES) requires downstream 5′ viral polyprotein-coding sequence for…”
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arterivirus replicase is the only viral protein required for genome replication and subgenomic mRNA transcription by Molenkamp, R, Tol, H. van, Rozier, B.C.D, Meer, Y. van der, Spaan, W.J.M, Snijder, E.J

“…Equine arteritis virus (EVA) (Arteriviridae) encodes several structural proteins. Whether any of these also function in viral RNA synthesis is unknown. For the…”
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An infectious arterivirus cDNA clone: identification of a replicase point mutation that abolishes discontinuous mRNA transcription by Dinten, L.C. van (Leiden Univ., Leiden, Netherlands.), Boon, J.A. den, Wassenaar, A.L.M, Spaan, W.J.M, Snijder, E.J

“…Equine arteritis virus (EAV) is a positive-strand RNA virus that uses a discontinuous transcription mechanism to generate a nested set of six subgenomic mRNAs…”
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Mutations in the NS5A gene and hepatits C virus resistance to interferon: solving the controversy by Schinkel, J., Spaan, W.J.M., Kroes, A.C.M.

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Rescue of disabled infectious single-cycle (DISC) Equine arteritis virus by using complementing cell lines that express minor structural glycoproteins by Zevenhoven-Dobbe, J.C, Greve, S, Tol, H. van, Spaan, W.J.M, Snijder, E.J

“…Molecular Virology Laboratory, Department of Medical Microbiology, Center of Infectious Diseases, Leiden University Medical Center, LUMC E4-P, Room P4-26, PO…”
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Processing of the equine arteritis virus replicase ORF1b protein: identification of cleavage products containing the putative viral polymerase and helicase domains by Dinten, L.C. van (Leiden University, Leiden, The Netherlands.), Wassenaar, A.L.M, Gorbalenya, A.E, Spaan, W.J.M, Snijder, E.J

“…The replicase open reading frame 1b (ORF1b) protein of equine arteritis virus (EAV) is expressed from the viral genome as an ORF1ab fusion protein (345 kDa) by…”
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Characterization of an equine arteritis virus replicase mutant defective in subgenomic mRNA synthesis by Marle, G. van, Dinten, L.C. van, Spaan, W.J.M, Luytjes, W, Snijder, E.J

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Proteolytic processing of the replicase ORF1a protein of equine arteritis virus by Snijder, E.J, Wassenaar, A.L.M, Spaan, W.J.M

“…To study the proteolytic processing of the equine arteritis virus (EAV) replicase open reading frame 1a (ORF1a) protein, specific antisera were raised in…”
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Equine arteritis virus is not a togavirus but belongs to the coronaviruslike superfamily by Boon, J.A. den (Leiden University, Leiden, The Netherlands), Snijder, E.J, Chirnside, E.D, Vries, A.A.F. de, Horzinek, M.C, Spaan, W.J.M

“…The nucleotide sequence of the genome of equine arteritis virus (EAV) was determined from a set of overlapping cDNA clones and was found to contain eight open…”
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Isolation and characterization of an arterivirus defective interfering RNA genome by Molenkamp, R, Rozier, B.C.D, Greve, S, Spaan, W.J.M, Snijder, E.J

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Early death after feline infectious peritonitis virus challenge due to recombinant vaccinia virus immunization by VENNEMA, H, DE GROOT, R. J, HARBOUR, D. A, DALDERUP, M, GRUFFYDD-JONES, T, HORZINEK, M. C, SPAAN, W. J. M

“…The gene encoding the fusogenic spike protein of the coronavirus causing feline infectious peritonitis was recombined into the genome of vaccinia virus. The…”
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Equine arteritis virus subgenomic mRNA synthesis: analysis of leader-body junctions and replicative-form RNAs by Boon, J.A. den (Leiden University, Leiden, The Netherlands.), Kleijnen, M.F, Spaan, W.J.M, Snijder, E.J

“…In addition to the genomic RNA, a 3' coterminal nested set of six subgenomic mRNAs is produced in equine arteritis virus (EAV)-infected cells. The seven viral…”
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Assembly of empty capsids by using baculovirus recombinants expressing human parvovirus B19 structural proteins by Brown, C S, Van Lent, J W, Vlak, J M, Spaan, W J

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The 5' end of the equine arteritis virus replicase gene encodes a papainlike cysteine protease by Snijder, E.J. (Leiden University, Leiden, The Netherlands), Wassenaar, A.L.M, Spaan, W.J.M

“…The presence of a papainlike cysteine protease (PCP) domain in the N-terminal region of the equine arteritis virus (EAV) replicase, which had been postulated…”
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Equine Arteritis Virus Subgenomic RNA Transcription: UV Inactivation and Translation Inhibition Studies by DEN BOON, JOHAN A., SPAAN, WILLY J.M., SNIJDER, ERIC J.

“…The expression of the genetic information of equine arteritis virus (EAV), an arterivirus, involves the synthesis of six subgenomic (sg) mRNAs. These are 5′…”
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Human rhinovirus (HRV) 16 infection in mild asthmatics induces an influx of neutrophils and increased expression of IL-8 in the nasal mucosa by Cazemier, H., Grünberg, K., de Kluijver, J., Smits, H.H., Spaan, W.J.M., Sterk, P.J., Hiemstra, P.S.

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