Search Results - "Sozu, Takashi"

Flexible use of copula‐type model for dose‐finding in drug combination clinical trials by Hashizume, Koichi, Tshuchida, Jun, Sozu, Takashi

“…Identification of the maximum tolerated dose combination (MTDC) of cancer drugs is an important objective in phase I oncology trials. Numerous dose‐finding…”
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Improvement of Midpoint Imputation for Estimation of Median Survival Time for Interval-Censored Time-to-Event Data by Nakagawa, Yuki, Sozu, Takashi

“…Progression-free survival (PFS) is used to evaluate treatment effects in cancer clinical trials. Disease progression (DP) in patients is typically determined…”
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Effects of Cryotherapy on Objective and Subjective Symptoms of Paclitaxel-Induced Neuropathy: Prospective Self-Controlled Trial by Hanai, Akiko, Ishiguro, Hiroshi, Sozu, Takashi, Tsuda, Moe, Yano, Ikuko, Nakagawa, Takayuki, Imai, Satoshi, Hamabe, Yoko, Toi, Masakazu, Arai, Hidenori, Tsuboyama, Tadao

“…Chemotherapy-induced peripheral neuropathy (CIPN) is a dose-limiting and disabling side effect of taxane anticancer agents. We prospectively evaluated the…”
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Using horseshoe prior for incorporating multiple historical control data in randomized controlled trials by Ohigashi, Tomohiro, Maruo, Kazushi, Sozu, Takashi, Gosho, Masahiko

“…Meta-analytic approaches and power priors are often used to incorporate historical controls into the analysis of a current randomized controlled trial. In this…”
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Optimal adaptive allocation using deep reinforcement learning in a dose‐response study by Matsuura, Kentaro, Honda, Junya, El Hanafi, Imad, Sozu, Takashi, Sakamaki, Kentaro

“…Estimation of the dose‐response curve for efficacy and subsequent selection of an appropriate dose in phase II trials are important processes in drug…”
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Impact of Donor Age on Recipient Survival in Adult-to-Adult Living-donor Liver Transplantation by Kubota, Toyonari, Hata, Koichiro, Sozu, Takashi, Ueda, Yoshihide, Hirao, Hirofumi, Okamura, Yusuke, Tamaki, Ichiro, Yoshikawa, Junichi, Kusakabe, Jiro, Tanaka, Hirokazu, Kageyama, Shoichi, Anazawa, Takayuki, Yoshizawa, Atsushi, Yagi, Shintaro, Yamashiki, Noriyo, Okajima, Hideaki, Kaido, Toshimi, Uemoto, Shinji

“…OBJECTIVE:To investigate the influence of donor age on recipient outcome after living-donor partial liver transplantation (LDLT). BACKGROUND:Donor age is a…”
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Group Cognitive-Behavioral Therapy With Interoceptive Exposure for Drug-Refractory Irritable Bowel Syndrome: A Randomized Controlled Trial by Kikuchi, Shino, Oe, Yuki, Ito, Yuri, Sozu, Takashi, Sasaki, Yohei, Sakata, Masatsugu, Luo, Yan, Sahker, Ethan, Horikoshi, Masaru, Seno, Hiroshi, Furukawa, Toshi A.

“…Few people can access psychotherapy for irritable bowel syndrome (IBS). Group cognitive-behavioral therapy (GCBT) may be efficient, but the evidence for its…”
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Systematic review and meta-analysis of prognostic factors for idiopathic inflammatory myopathy-associated interstitial lung disease by Kamiya, Hiroyuki, Panlaqui, Ogee Mer, Izumi, Shinyu, Sozu, Takashi

“…ObjectiveTo clarify prognostic factors for idiopathic inflammatory myopathy (IIM)-associated interstitial lung disease (ILD).DesignSystematic review and…”
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Matrix decomposition in meta‐analysis for extraction of adverse event pattern and patient‐level safety profile by Matsuura, Kentaro, Tsuchida, Jun, Ando, Shuji, Sozu, Takashi

“…The purpose of assessing adverse events (AEs) in clinical studies is to evaluate what AE patterns are likely to occur during treatment. In contrast, it is…”
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Longitudinal effects of one‐leg standing time on neuropathy outcomes in association with glycemic control in non‐elderly patients with type 2 diabetes by Sugimoto, Kazuhiro, Sozu, Takashi, Hoshino, Takehiko, Watanabe, Yuko, Tamura, Akira, Yamazaki, Toshiro, Ohta, Setsu, Suzuki, Susumu, Shimbo, Takuro

“…Aims/Introduction Diabetic neuropathy leads to postural instability. This study compared longitudinal changes in neuropathy outcomes relative to long‐term…”
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Sizing clinical trials when comparing bivariate time‐to‐event outcomes by Sugimoto, Tomoyuki, Hamasaki, Toshimitsu, Evans, Scott R., Sozu, Takashi

“…Clinical trials with multiple primary time‐to‐event outcomes are common. Use of multiple endpoints creates challenges in the evaluation of power and the…”
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Associations of age‐adjusted coefficient of variation of R‐R intervals with autonomic and peripheral nerve function in non‐elderly persons with diabetes by Sugimoto, Kazuhiro, Miyaoka, Hirozumi, Sozu, Takashi, Sekikawa, Naohiro, Wada, Ryota, Watanabe, Yuko, Tamura, Akira, Yamazaki, Toshiro, Ohta, Setsu, Suzuki, Susumu

“…ABSTRACT Aims/Introduction Early diagnosis of diabetes‐associated cardiac autonomic neuropathy using the coefficient of variation of R‐R intervals (CVRR) may…”
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Statin treatment for coronary artery plaque composition based on intravascular ultrasound radiofrequency data analysis by Nozue, Tsuyoshi, MD, Yamamoto, Shingo, MD, Tohyama, Shinichi, MD, Umezawa, Shigeo, MD, Kunishima, Tomoyuki, MD, Sato, Akira, MD, Miyake, Shogo, MD, Takeyama, Youichi, MD, Morino, Yoshihiro, MD, Yamauchi, Takao, MD, Muramatsu, Toshiya, MD, Hibi, Kiyoshi, MD, Sozu, Takashi, PhD, Terashima, Mitsuyasu, MD, Michishita, Ichiro, MD

“…Background Systemic therapy with statin has been shown to lower the risk of coronary events; however, the in vivo effects of statin therapy on plaque volume…”
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Efficacy of azilsartan on left ventricular diastolic dysfunction compared with candesartan: J-TASTE randomized controlled trial by Ito, Shin, Takahama, Hiroyuki, Asakura, Masanori, Abe, Yukio, Ajioka, Masayoshi, Anzai, Toshihisa, Arikawa, Takuo, Hayashi, Takaharu, Higashino, Yorihiko, Hiramitsu, Shinya, Iwahashi, Noriaki, Izumi, Chisato, Kimura, Kazuo, Kinugawa, Koichiro, Kioka, Hidetaka, Lim, Young-Jae, Matsuoka, Ken, Matsuoka, Satoshi, Motoki, Hirohiko, Nakamura, Sunao, Nakayama, Takafumi, Nomura, Akihiro, Sasaoka, Taishi, Takiuchi, Shin, Toyoda, Shigeru, Ueda, Tomoya, Watanabe, Tetsuya, Yamada, Akira, Yamamoto, Masayoshi, Sozu, Takashi, Kitakaze, Masafumi

“…Characterized by ventricular and vascular stiffness, heart failure with preserved ejection fraction (HFpEF) has led to high morbidity and mortality. As…”
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Effects of lifestyle advice provided by pharmacists on blood pressure: The COMmunity Pharmacists ASSist for Blood Pressure (COMPASS-BP) randomized trial by Okada, Hiroshi, Onda, Mitsuko, Shoji, Masaki, Sakane, Naoki, Nakagawa, Yasushi, Sozu, Takashi, Kitajima, Yui, Tsuyuki, Ross T., Nakayama, Takeo

“…The COMmunity Pharamcists ASSist for Blood Pressure (COMPASS-BP) study aimed to assess the effectiveness of lifestyle support programs administered in…”
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Sense of meaning in work and risk of burnout among medical professionals by Tei, Shisei, Becker, Carl, Sugihara, Genichi, Kawada, Ryosaku, Fujino, Junya, Sozu, Takashi, Murai, Toshiya, Takahashi, Hidehiko

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Self‐efficacy modulates the neural correlates of craving in male smokers and ex‐smokers: an fMRI study by Ono, Miki, Kochiyama, Takanori, Fujino, Junya, Sozu, Takashi, Kawada, Ryosaku, Yokoyama, Naoto, Sugihara, Genichi, Murai, Toshiya, Takahashi, Hidehiko

“…The regulation of cue‐induced craving for cigarettes is a key factor in smoking cessation. Outcomes of smoking cessation have been linked to self‐efficacy,…”
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Group cognitive behavioural therapy (GCBT) versus treatment as usual (TAU) in the treatment of irritable bowel syndrome (IBS): a study protocol for a randomized controlled trial by Kikuchi, Shino, Oe, Yuki, Sasaki, Yohei, Ishii, Hirono, Ito, Yuri, Horikoshi, Masaru, Sozu, Takashi, Seno, Hiroshi, Furukawa, Toshi A

“…Irritable bowel syndrome (IBS) is a common disease that affects the quality of life (QOL) and social functioning of sufferers. Visceral anxiety is currently…”
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Risk Factors for Progression of Degenerative Aortic Valve Disease in the Japanese　– The Japanese Aortic Stenosis Study (JASS) Prospective Analysis by Yamamoto, Kazuhiro, Yamamoto, Hideya, Takeuchi, Masaaki, Kisanuki, Akira, Akasaka, Takashi, Ohte, Nobuyuki, Hirano, Yutaka, Yoshida, Kiyoshi, Nakatani, Satoshi, Takeda, Yasuharu, Sozu, Takashi, Masuyama, Tohru

“…Background:Because of ethnic difference in the risk of degenerative aortic valve disease (DAVD), risk factors should be clarified in each race to establish…”
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Identification of High-Risk Groups in Urinalysis: Lessons from the Longitudinal Analysis of Annual Check-Ups by Matsuzaki, Keiichi, Ohigashi, Tomohiro, Sozu, Takashi, Ishida, Mami, Kobayashi, Daisuke, Suzuki, Hitoshi, Suzuki, Yusuke, Kawamura, Takashi

“…Background: For effective screening in urinalysis, information on high-risk groups is needed; however, there is a lack of evidence in young adults in…”
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