Search Results - "Sozaeva, Zhannet A"
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Influence of ABCB1 3435C>T polymorphism on methotrexate safety in patients with psoriasis
Published in Vestnik dermatologij i venerologij (26-02-2023)“…Background. Methotrexate is a highly effective systemic treatment for moderate to severe psoriasis, but drug toxicity may limit its use. Recent evidence…”
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Analysis of the complications of endocrine therapy with tamoxifen in breast cancer: clinical and pharmacogenetic aspects. Prospective pharmacogenetic cohort study
Published in Sovremennaia onkologiia : zhurnal kafedry onkologii RMAPO dlia nepreryvnogo poslediplomnogo obrazovaniia (25-11-2022)“…Background. Tamoxifen is the drug of choice in ER-positive breast cancer (BC) therapy for perimenopausal women and one of the endocrine therapy options for…”
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CYP2D6 gene polymorphic markers role in determining the optimal treatment tactics for portal hypertension in patients with liver cirrhosis
Published in Terapevtic̆eskii arhiv (15-02-2022)“…Aim. To study the polymorphic markers CYP2D6*4 (G1846A, rs3892097), CYP2D6*6 (T1707del, rs5030655), CYP2D6*10 (C100T, rs1065852), CYP2D6*41 (G2988A,…”
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Evaluation of the association of polymorphisms of the CYP2C8 gene with the efficacy and safety of ketorolac in patients with postoperative pain syndrome
Published in Terapevtic̆eskii arhiv (17-06-2022)“…Aim. To evaluate the possible association of CYP2C8 gene polymorphisms with the clinical efficacy and safety of ketorolac in relation to postoperative pain…”
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CYP2C8, PTGS-1, 2 gene polymorphisms prevalence associated with sensitivity to non-steroidal anti-inflammatory drugs among North Caucasus ethnic groups
Published in Terapevtic̆eskii arhiv (15-11-2021)“…Aim. Find the prevalence of CYP2C8*3 (rs10509681; rs11572080), PTGS-1 (rs10306135; rs12353214) and PTGS-2 (rs20417) alleles and genotypes in four ethnic groups…”
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Antihypertensive Effect Of Amlodipine In Co-Administration With Omeprazole In Patients With Hypertension And Acid-Related Disorders: Cytochrome P450-Associated Aspects
Published in Pharmacogenomics and personalized medicine (01-01-2019)“…CYP2C19 and CYP3A are the main enzymes involved in omeprazole metabolism, while CYP3A is the principal enzyme family for amlodipine biotransformation…”
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CYP3A and CYP2C19 activity in urine in relation to CYP3A4, CYP3A5, and CYP2C19 polymorphisms in Russian peptic ulcer patients taking omeprazole
Published in Pharmacogenomics and personalized medicine (01-01-2018)“…Proton pump inhibitors (PPIs) are metabolized by cytochrome P450. CYP2C19 is the main isoenzyme for the majority of PPI, whereas CYP3A family is a secondary…”
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Opportunities of the pharmacogenetic approach to personalized tamoxifen breast cancer therapy: case reports
Published in Sovremennaia onkologiia : zhurnal kafedry onkologii RMAPO dlia nepreryvnogo poslediplomnogo obrazovaniia (15-03-2019)“…Tamoxifen is the selective modulator of estrogen receptors. Nowadays, it is widely used for treatment of premenopausal women with ER(+) breast cancer likewise…”
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Urine metabolic ratio of omeprazole in relation to CYP2C19 polymorphisms in Russian peptic ulcer patients
Published in Pharmacogenomics and personalized medicine (01-01-2017)“…CYP2C19 is known to be the main enzyme of biotransformation of proton pump inhibitors (PPIs), whereas the gene is highly polymorphic. Genotyping and…”
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Do CYP2C19 and ABCB1 gene polymorphisms and low CYP3A4 isoenzyme activity have an impact on stent implantation complications in acute coronary syndrome patients?
Published in Pharmacogenomics and personalized medicine (01-01-2017)“…The aim of this study was to determine the impact of and gene polymorphisms and CYP3A4 isoenzyme activity on stent implantation complications among patients…”
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Evaluation of the association of CES1 (rs2244613) polymorphisms with the safety of remdesivir in hospitalized patients with COVID-19
Published in Medicinskij sovet (18-01-2023)“…Introduction . An outbreak of novel COVID-19 infection has become a real challenge for the entire human society, and first of all for the healthcare services…”
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Effect of polymorphisms in CYP3A422 (rs35599367) C>T, CYP3A53 (rs776746) A>G, ABCB1 (rs4148738) C>T and ABCB1 (rs1045642) C>T genes on apixaban anticoagulation: pilot study results
Published in Medicinskij sovet (20-04-2021)“…Introduction . Apixaban is a direct oral anticoagulant prescribed for treatment and prevention of venous thromboembolism (VTE) and for prevention of stroke in…”
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Do CYP2C 19 and ABCB1 gene polymorphisms and low CYP3A4 isoenzyme activity have an impact on stent implantation complications in acute coronary syndrome patients?
Published in Pharmacogenomics and personalized medicine (01-01-2017)“…Aim: The aim of this study was to determine the impact of CYP2C19 and ABCB1 gene polymorphisms and CYP3A4 isoenzyme activity on stent implantation…”
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Urine metabolic ratio of omeprazole in relation to CYP2C 19 polymorphisms in Russian peptic ulcer patients
Published in Pharmacogenomics and personalized medicine (01-01-2017)“…Background: CYP2C 19 is known to be the main enzyme of biotransformation of proton pump inhibitors (PPIs), whereas the CYP2C19 gene is highly polymorphic…”
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Do CYP2C19 andABCB1 gene polymorphisms and low CYP3A4 isoenzyme activity have an impact on stent implantation complications in acute coronary syndrome patients?
Published in Pharmacogenomics and personalized medicine (01-01-2017)“…Aim: The aim of this study was to determine the impact of CYP2C19 and ABCB1gene polymorphisms and CYP3A4 isoenzyme activity on stent implantation complications…”
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Effect of CYP2C9 , PTGS-1 and PTGS-2 gene polymorphisms on the efficiency and safety of postoperative analgesia with ketoprofen
Published in Drug metabolism and personalized therapy (01-12-2022)“…Patients undergoing cardiac surgery develop post-sternotomy pain syndrome. The aim of this study was evaluation of the influence of , and genes polymorphisms…”
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